Terwijl ze op een vlucht naar huis zijn vanuit Colombia, wordt het vliegtuig waarin Dr. Carrie Ross en haar dochter zich bevinden, aangevallen door kogelmieren wier steek de meest pijnlijke en dodelijkste ter wereld is. Dr. Ross, een entomoloog, bundelt zijn krachten met luchtmaarschalk Ethan Hart en probeert wanhopig de vlucht van een ramp te redden. Uiteindelijk brengt hun strijd hen dichter bij elkaar en biedt het koppel hoop voor de toekomst.
Nee, helaas is Destination: Infestation nog niet beschikbaar op Netflix in Nederland.
| Writing | Mary Weinstein | Writer |
| Production | Kirk Shaw | Producer |
| Camera | Michael Balfry | Director of Photography |
| Editing | Joel Snowden | Editor |
| Art | Hitoshi Okamoto | Production Design |
| Art | Joel Fisher | Set Decoration |
| Directing | George Mendeluk | Director |
| Camera | Ivan Maldonado | "A" Camera Operator |
| Camera | Richard Schmon | First Assistant "A" Camera |
| Camera | Richard McSeeney | Second Assistant "A" Camera |
| Camera | Jill MacLauchlan | "B" Camera Operator |
| Camera | Kyle Brown | First Assistant "B" Camera |
| Camera | Ray Wong | Digital Imaging Technician |
| Camera | Katie Yu | Still Photographer |
| Sound | Mark Noda | Sound Mixer |
| Sound | Simon Bright | Boom Operator |
| Art | Tashanna Ducharme | Assistant Art Director |
| Art | Gabriel Spear | Assistant Set Decoration |
| Costume & Make-Up | Elliott Cufaro | On Set Dresser |
| Costume & Make-Up | Michael Richen | Dresser |
| Costume & Make-Up | Shanna Mair | Assistant Costume Designer |
| Art | Erin Evans | Set Supervisor |
| Costume & Make-Up | Lindsay Borowko | Truck Costumer |
| Lighting | Jim Swanson | Gaffer |
| Lighting | Geoff Dane | Best Boy Electric |
| Crew | Greg Hartley | Generator Operator |
| Camera | Tony Derkatsch | Best Boy Grip |
| Camera | David Walker | Key Grip |
| Camera | Jules Quesnel | Dolly Grip |
| Camera | Angela Liebenberg | Grip |
| Camera | Sean Jobin | Grip |
| Production | Karen Zajac | Location Manager |
| Production | Ken Meisenbacher | Assistant Location Manager |
| Production | Mike Farias | Key Production Assistant |
| Production | Scott Outwaite | Location Production Assistant |
| Production | Dale Bredeson | Location Production Assistant |
| Crew | Owen Walstrom | Stunt Coordinator |
| Crew | Chris Labre | Special Effects Assistant |
| Crew | John McNulty | Special Effects Assistant |
| Costume & Make-Up | Monica Huppert | Key Makeup Artist |
| Costume & Make-Up | Megan Davies | Assistant Makeup Artist |
| Crew | Todd Masters | Makeup Effects |
| Production | Sarah Rogers | Unit Manager |
| Production | Kasandra Greene | Production Coordinator |
| Production | Angela Lamb | Assistant Production Coordinator |
| Production | Jamie Tait | Assistant Production Coordinator |
| Directing | Alex Burnett | Third Assistant Director |
| Directing | Tammy Tamkin | Assistant Director Trainee |
| Crew | Tara Fuhre | Craft Service |
| Crew | Michael Zwart | Chef |
| Crew | Lilly Workentin | Assistant Chef |
| Crew | Doran Chandler | Legal Services |
| Crew | Sarah Terry | Legal Services |
| Production | Edward Rea | Casting Assistant |
| Production | L.A. Hilts | Extras Casting |
| Production | Karen Austin | Production Accountant |
| Production | Bryant Pike | Controller |
| Production | Leah Tanafranca | Payroll Accountant |
| Production | Mai-Britt Kotzman | Payroll Accountant |
| Production | Linda Sims | Post Production Accountant |
| Production | Valentina Carp | Post Production Accountant |
| Crew | Randy Caine | Transportation Coordinator |
| Crew | Jim Stewart | Transportation Captain |
| Crew | Alvin Ram | Cast Driver |
| Crew | Randy Clair | Security Coordinator |
| Crew | Charlotte Clark | Post Production Supervisor |
| Crew | Todd Giroux | Technical Supervisor |
| Production | William Higgins | Post Production Coordinator |
| Editing | Mark Yuen | First Assistant Editor |
| Editing | Ronald Ramage | Online Editor |
| Visual Effects | Paul Cox | Visual Effects Supervisor |
| Visual Effects | Gregg Vallieres | Visual Effects Coordinator |
| Lighting | Jeremy Sabo | Rigging Supervisor |
| Visual Effects | David Cheng | Modeling |
| Visual Effects | Jonathan Sibayan | Modeling |
| Visual Effects | Chris Woods | Animation |
| Sound | Derick Cobden | Sound Supervisor |
| Sound | Matthew Gionet | Sound Supervisor |
| Sound | Chris Ove | Dialogue Editor |
| Sound | Mario Loubert | Sound Effects Editor |
| Sound | Chester Biolowas | Sound Effects Editor |
| Sound | Michael Keeping | Foley Artist |
| Sound | Peter Allen | Orchestrator |
| Sound | Vince Mai | Orchestrator |
| Crew | Charlene Paling | Thanks |
| Crew | Jonathan Dyck | Thanks |
| Costume & Make-Up | Rebekka Sorensen | Costume Design |
| Production | John Prince | Production Manager |
| Directing | Kevin Speckmaier | First Assistant Director |
| Directing | Sara Irvine-Erickson | Second Assistant Director |
| Production | Randy Zalken | Associate Producer |
| Production | Stacey Shaw | Associate Producer |
| Production | Barry Perelman | Executive Producer |
| Production | Lindsay MacAdam | Co-Producer |
| Production | Timothy O. Johnson | Executive Producer |
| Crew | Allen Benjamin | Special Effects Coordinator |
| Directing | Susan Williams | Script Supervisor |
| Sound | Peter Allen | Original Music Composer |
| Sound | Vincent Mai | Original Music Composer |
