DJay is een klein pooiertje uit Memphis die verwoede pogingen doet een carrière als rapper van de grond te krijgen. Hij probeert zijn debuutalbum op de markt te krijgen, met behulp van zijn vrienden uit de 'hood'. Wanneer hij hoort dat rap-superster Skinny Black de omgeving zal bezoeken, zet DJay een plannetje op poten om de aandacht van de ster te krijgen.
Nee, helaas is Hustle & Flow nog niet beschikbaar op Netflix in Nederland.
| Editing | Billy Fox | Editor |
| Camera | Amy Vincent | Director of Photography |
| Directing | Craig Brewer | Director |
| Production | John Singleton | Producer |
| Production | Kimberly Hardin | Casting |
| Sound | Scott Bomar | Original Music Composer |
| Costume & Make-Up | Paul A. Simmons Jr. | Costume Design |
| Production | Preston L. Holmes | Associate Producer |
| Production | Stephanie Allain | Producer |
| Directing | Ilene Pickus | Script Supervisor |
| Art | Keith Brian Burns | Production Design |
| Production | Dwight Williams | Executive Producer |
| Sound | Brian W. Jennings | Sound Designer |
| Sound | Shie Rozow | Music Editor |
| Sound | Marvin R. Morris | Music Editor |
| Sound | Paul Stewart | Music Supervisor |
| Sound | Michael C. Casper | Sound Re-Recording Mixer |
| Sound | Daniel J. Leahy | Sound Re-Recording Mixer |
| Sound | Frank Smathers | Supervising Sound Editor |
| Sound | Brian W. Jennings | Sound Effects Editor |
| Sound | James Azizi Penny | Sound Effects Editor |
| Sound | Nathan Black | Boom Operator |
| Production | Betty Chin | Production Coordinator |
| Sound | Greg Hedgepath | Supervising Sound Editor |
| Sound | Michael Camello | Sound Effects Editor |
| Writing | Craig Brewer | Writer |
| Sound | Fred Stafford | ADR Editor |
| Sound | DJ Paul | Music Producer |
| Sound | Frayser Boy | Music Producer |
| Sound | Juicy J | Music Producer |
| Sound | Paul Hackner | Dialogue Editor |
| Sound | Stephanie Flack | Dialogue Editor |
| Sound | Susan Kurtz | Dialogue Editor |
| Art | Alexa Marino | Art Direction |
| Art | Darian Corley | Property Master |
| Sound | Bobbi Banks | Supervising ADR Editor |
| Directing | Van Hayden | First Assistant Director |
| Art | Joni Wheeler | Set Decoration |
