De rechtbank heeft Norman Bates, de moordenaar van zijn moeder en twee andere personen uit het eerste deel, officiëel genezen verklaard. Na 22 jaar in een psychiatrische inrichting, keert Norman terug naar het oude familiemotel. Als snel wordt het motel wederom het decor van een aantal onverklaarbare moorden.
Nee, helaas is Psycho II nog niet beschikbaar op Netflix in Nederland.
| Writing | Robert Bloch | Characters |
| Production | Hilton A. Green | Producer |
| Directing | Richard Franklin | Director |
| Art | John W. Corso | Production Design |
| Camera | Dean Cundey | Director of Photography |
| Production | Bernard Schwartz | Executive Producer |
| Editing | Andrew London | Editor |
| Sound | Jerry Goldsmith | Original Music Composer |
| Writing | Tom Holland | Writer |
| Camera | Raymond Stella | Camera Operator |
| Directing | Don Zepfel | First Assistant Director |
| Camera | Ronald Batzdorff | Still Photographer |
| Crew | Bob Yerkes | Stunts |
| Art | Martha Johnston | Set Designer |
| Crew | Greg C. Jensen | Special Effects |
| Directing | Lisa Marmon | Second Assistant Director |
| Art | Jennifer Polito | Set Decoration |
| Costume & Make-Up | Marla Schlom | Costume Design |
| Production | Jackie Burch | Casting |
| Costume & Make-Up | Peter V. Saldutti | Costume Design |
| Sound | Randy Kelley | Sound Effects Editor |
| Sound | Patrick Clark | Boom Operator |
| Costume & Make-Up | Brian Wade | Makeup Effects Designer |
| Sound | Lon Bender | Sound Editor |
| Sound | Bob Newlan | Foley Editor |
| Sound | Mark Server | Boom Operator |
| Sound | Anthony Milch | Sound Editor |
| Sound | James R. Alexander | Sound Mixer |
| Sound | Andrew London | Sound Designer |
| Sound | Michael D. Wilhoit | Sound Editor |
| Sound | Gordon Ecker | Supervising Sound Editor |
| Sound | John Roesch | Foley Artist |
| Sound | Glenn T. Morgan | Assistant Sound Editor |
