De rechtbank heeft Norman Bates, de moordenaar van zijn moeder en twee andere personen uit het eerste deel, officiëel genezen verklaard. Na 22 jaar in een psychiatrische inrichting, keert Norman terug naar het oude familiemotel. Als snel wordt het motel wederom het decor van een aantal onverklaarbare moorden.
Nee, helaas is Psycho II nog niet beschikbaar op Netflix in Nederland.
| Editing | Andrew London | Editor |
| Production | Bernard Schwartz | Executive Producer |
| Writing | Tom Holland | Writer |
| Production | Hilton A. Green | Producer |
| Writing | Robert Bloch | Characters |
| Art | John W. Corso | Production Design |
| Directing | Richard Franklin | Director |
| Camera | Dean Cundey | Director of Photography |
| Sound | Jerry Goldsmith | Original Music Composer |
| Camera | Ronald Batzdorff | Still Photographer |
| Directing | Lisa Marmon | Second Assistant Director |
| Crew | Bob Yerkes | Stunts |
| Art | Martha Johnston | Set Designer |
| Camera | Raymond Stella | Camera Operator |
| Directing | Don Zepfel | First Assistant Director |
| Crew | Greg C. Jensen | Special Effects |
| Costume & Make-Up | Peter V. Saldutti | Costume Design |
| Production | Jackie Burch | Casting |
| Art | Jennifer Polito | Set Decoration |
| Costume & Make-Up | Marla Schlom | Costume Design |
| Sound | Glenn T. Morgan | Assistant Sound Editor |
| Costume & Make-Up | Brian Wade | Makeup Effects Designer |
| Sound | Andrew London | Sound Designer |
| Sound | Michael D. Wilhoit | Sound Editor |
| Sound | Lon Bender | Sound Editor |
| Sound | Anthony Milch | Sound Editor |
| Sound | Patrick Clark | Boom Operator |
| Sound | Mark Server | Boom Operator |
| Sound | James R. Alexander | Sound Mixer |
| Sound | Bob Newlan | Foley Editor |
| Sound | Gordon Ecker | Supervising Sound Editor |
| Sound | Randy Kelley | Sound Effects Editor |
| Sound | John Roesch | Foley Artist |
