De film begint zes jaar na de serie. Alf is gevangen door de Alien Task Force en wordt nu vastgehouden in een geheime basis in de woestijn (gelijk aan Area 51). Het leger houdt hem nauw in de gaten. Wanneer blijkt dat het project zal worden gesloten, geeft kolonel Milfoil het bevel Alf te laten executeren. Twee medewerkers van het project, Dr. Rick Mullican en Dr. Melissa Hill, besluiten Alf te redden. Ze smokkelen hem de basis uit en nemen hem mee naar een paar collega-wetenschappers. Die willen Alf aan de hele wereld tonen.
Nee, helaas is Project: ALF nog niet beschikbaar op Netflix in Nederland.
| Editing | William B. Stich | Editor |
| Sound | Mark Snow | Original Music Composer |
| Production | Kenneth Kaufman | Executive Producer |
| Writing | Tom Patchett | Screenplay |
| Production | Tom Patchett | Producer |
| Directing | Dick Lowry | Director |
| Writing | Paul Fusco | Screenplay |
| Production | Paul Fusco | Executive Producer |
| Camera | Henry M. Lebo | Director of Photography |
| Production | Ann Kindberg | Unit Production Manager |
| Crew | J. Armin Garza II | Driver |
| Production | Ann Kindberg | Supervising Producer |
| Production | Debbie Smith | Associate Producer |
| Costume & Make-Up | Gwyne Redner | Hairstylist |
| Directing | C.C. Barnes | Second Assistant Director |
| Directing | Bob Dahlin | First Assistant Director |
| Costume & Make-Up | Robin Wright | Costume Supervisor |
| Art | Ken Masi | Construction Coordinator |
| Camera | Leslie R. Morris | First Assistant Camera |
| Camera | Ralph Watson | Camera Operator |
| Crew | Sean Whitler | Set Production Assistant |
| Camera | Michael Stecher | First Assistant "B" Camera |
| Lighting | Vincent Torres | Best Boy Electric |
| Costume & Make-Up | Deborah Humphries | Makeup Department Head |
| Directing | Catherine Bond | Second Second Assistant Director |
| Crew | Leslie Ann Podkin | Technical Advisor |
| Art | Chip Radaelli | Art Direction |
| Art | Guy Barnes | Production Design |
| Art | Wendy Ozols-Barnes | Set Decoration |
| Art | Barbara Benz | Property Master |
| Production | Steve Spiker | Extras Casting |
| Sound | Michael A. Patillo | Boom Operator |
| Editing | Robert McFalls | Assistant Editor |
| Lighting | Alan Goldenhar | Gaffer |
| Editing | Mace Johnson | Colorist |
| Sound | Marty Wereski | Music Editor |
| Directing | Anne Melville | Script Supervisor |
| Camera | Todd Griffith | Key Grip |
| Production | Wolf Bauer | Producer |
| Costume & Make-Up | Laverne Caracuzzi | Key Makeup Artist |
| Sound | Brian Bidder | Sound Mixer |
| Production | Ron Surma | Casting Associate |
| Crew | Peter R. Chittell | Transportation Coordinator |
| Production | Brad Uecker | Production Supervisor |
| Costume & Make-Up | Jon Boyden | Costume Design |
| Art | John Bratton | Set Dresser |
| Production | Junie Lowry-Johnson | Casting |
| Production | Marjorie Kaye | Location Manager |
| Production | Chuck Conway | Production Coordinator |
| Lighting | Melvin Pukowsky | Electrician |
| Art | Chuck Courrieu | Set Dresser |
| Camera | Ralph Watson | Steadicam Operator |
