De meest meedogenloze buitenaardse monsters bundelen hun krachten om de aarde te veroveren. Gelukkig worden ze tegengewerkt door de heldhaftige Ultraman Mebius die een nazaat is van de "Ultra Brothers", die onze planeet 40 jaar lang beschermd hebben. De monsters laten de monsterachtige Ultra Killer Zarus, die in de jaren 80 verslagen werd door de Ultra Brothers, verrijzen. Ultraman Mebius kan de grote overmacht niet aan en moet het onderspit delven. Dan komen de Ultra Brothers hem te hulp na een afwezigheid van 20 jaar.
Nee, helaas is ウルトラマンメビウス&ウルトラ兄弟 nog niet beschikbaar op Netflix in Nederland.
| Directing | 小中和哉 | Director |
| Art | Tetsuzô Ôsawa | Art Direction |
| Production | Takatoshi Kobayashi | Producer |
| Sound | 佐橋俊彦 | Music |
| Production | Takeyuki Okazaki | Producer |
| Visual Effects | 小中和哉 | Special Effects Supervisor |
| Sound | Tsubasa Nakamura | Sound Effects |
| Lighting | Masakatsu Izumi | Lighting Technician |
| Production | Shigeru Maruzawa | Producer |
| Editing | Akira Matsuki | Editor |
| Sound | 岡瀬晶彦 | Sound Effects |
| Production | Kiyoshi Suzuki | Executive Producer |
| Art | Masato Inatsuki | Art Designer |
| Production | Takuyuki Matsuno | Production Manager |
| Sound | Naoto Kobayashi | Sound Effects |
| Production | 伍賀一統 | Producer |
| Crew | Kunihide Kuruma | Fight Choreographer |
| Sound | Shizuka Tamagawa | Music Producer |
| Camera | Hajime Takahashi | Director of Photography |
| Sound | Kazuharu Urata | Recording Supervision |
| Sound | Kazuo Kumada | Music Director |
| Art | 山下順弘 | Decorator |
| Production | Satoshi Kubo | Producer |
| Visual Effects | 板野一郎 | CGI Director |
| Production | 竹中一博 | Producer |
| Production | Hiroaki Muto | Producer |
| Production | 山西太平 | Producer |
| Production | 寶諸明 | Producer |
| Writing | 長谷川圭一 | Writer |
