Revolverheld Hogan redt een nonnetje, zuster Sara, uit handen van een stel dronken bandieten. Vervolgens raken zij samen betrokken bij de Mexicaanse vrijheidsstrijd tegen de Fransen.
Nee, helaas is Two Mules for Sister Sara nog niet beschikbaar op Netflix in Nederland.
| Production | Carroll Case | Producer |
| Directing | Don Siegel | Director |
| Production | Martin Rackin | Producer |
| Sound | Ennio Morricone | Original Music Composer |
| Camera | Gabriel Figueroa | Director of Photography |
| Editing | Robert F. Shugrue | Editor |
| Writing | Albert Maltz | Screenplay |
| Crew | Leon Charles | Dialogue Coach |
| Crew | Buddy Van Horn | Stunt Coordinator |
| Sound | Stanley Wilson | Music Supervisor |
| Costume & Make-Up | Evelina Casas | Hairstylist |
| Sound | Ronald Pierce | Sound |
| Crew | Gabriel Torres | Second Unit Cinematographer |
| Sound | Waldon O. Watson | Sound |
| Costume & Make-Up | Helen Colvig | Costume Design |
| Crew | León Ortega | Special Effects |
| Costume & Make-Up | Margarita Ortega | Makeup Artist |
| Costume & Make-Up | Frank Westmore | Makeup Artist |
| Directing | Joseph C. Cavalier | Second Unit Director |
| Crew | Frank Brendel | Special Effects |
| Directing | Manuel Muñoz 'Torito' | Assistant Director |
| Production | Alfonso Sánchez Tello | Unit Production Manager |
| Editing | Juan José Marino | Editor |
| Production | William Davidson | Unit Production Manager |
| Directing | Joseph C. Cavalier | Assistant Director |
| Sound | Jesús González Gancy | Sound |
| Costume & Make-Up | Carlos Chávez | Costume Design |
| Directing | René Cardona | Second Unit Director |
| Art | José Rodríguez Granada | Art Direction |
| Art | Pablo Galván | Set Decoration |
| Writing | Budd Boetticher | Story |
