Vier onbekende mensen stappen op een avond in San Francisco nietsvermoedend in de bus. De buschauffeur wordt echter op zeer prettige wijze afgeleid en zij verongelukken allen. Tegelijkertijd wordt tijdens het ongeluk in een van de betrokken auto's Thomas geboren. En juist deze onwillige sterveling is voorbestemd om de onvervulde dromen van de vier ongelukkige zielen te doen uitkomen.
Nee, helaas is Heart and Souls nog niet beschikbaar op Netflix in Nederland.
| Sound | Marc Shaiman | Original Music Composer |
| Editing | O. Nicholas Brown | Editor |
| Production | Sean Daniel | Producer |
| Production | Nancy Roberts | Producer |
| Directing | Ron Underwood | Director |
| Camera | Michael W. Watkins | Director of Photography |
| Writing | Brent Maddock | Screenplay |
| Crew | Mic Rodgers | Stunt Coordinator |
| Crew | Michael Runyard | Stunts |
| Crew | Sonja Davis | Stunts |
| Crew | Adam Shankman | Choreographer |
| Crew | John C. Meier | Stunts |
| Visual Effects | Tom Martinek | I/O Supervisor |
| Writing | Brent Maddock | Screenstory |
| Art | Mike Helbig | Set Dresser |
| Art | Hugo Herrera | Greensman |
| Directing | Polly Ann Mattson | Second Second Assistant Director |
| Art | Gary Gagliardo | Construction Foreman |
| Art | Lori Harrison | Set Dresser |
| Production | Dirk Petersmann | Unit Production Manager |
| Directing | Daniel Silverberg | Second Assistant Director |
| Writing | Erik Hansen | Screenplay |
| Production | Erik Hansen | Co-Producer |
| Costume & Make-Up | Jean-Pierre Dorléac | Costume Design |
| Art | John Alvin | Other |
| Art | Steven Lane Ewing | Other |
| Writing | S.S. Wilson | Screenplay |
| Production | James Jacks | Executive Producer |
| Production | Dirk Petersmann | Line Producer |
| Writing | Gregory Hansen | Screenstory |
| Writing | S.S. Wilson | Screenstory |
| Production | Cari-Esta Albert | Executive Producer |
| Costume & Make-Up | James R. Scribner | Makeup Artist |
| Production | Dixie J. Capp | Associate Producer |
| Production | Gregory Hansen | Co-Producer |
| Costume & Make-Up | Ken Chase | Key Makeup Artist |
| Directing | Yudi Bennett | First Assistant Director |
| Costume & Make-Up | Karen Bradley | Makeup Artist |
| Costume & Make-Up | JoAnn Stafford-Chaney | Hairstylist |
| Writing | Gregory Hansen | Screenplay |
| Costume & Make-Up | Dione Taylor | Key Hair Stylist |
| Art | John Muto | Production Design |
| Art | Anne H. Ahrens | Set Decoration |
| Art | Kristin Argue | Other |
| Crew | David Castro, Jr. | Other |
| Art | Gary Heider | Other |
| Art | John M. Holliday | Construction Foreman |
| Art | Chris H. Kelly | Construction Foreman |
| Art | John Moore | Other |
| Crew | John Bullard | Propmaker |
| Art | Horst Grandt | Property Master |
| Art | Ross Harpold | Set Dresser |
| Art | Bill Jackson | Art Department Coordinator |
| Directing | Shawn Hanley | Other |
| Directing | Pamela S. Kuri | Second Second Assistant Director |
| Art | Dean B. Katz | Set Dresser |
| Crew | Allan Johnson | Other |
| Crew | Leopold Mouneau, Jr. | Other |
| Art | Robert L. King | Other |
| Production | Pam Dixon | Casting |
| Art | John Berger | Set Designer |
| Art | Danny Hinzo | Painter |
| Art | James Holden | Set Dresser |
| Art | Douglas E. Maxwell | Leadman |
| Writing | Erik Hansen | Screenstory |
| Art | Dan Webster | Art Direction |
| Art | Amy Feldman | Other |
| Art | Geoffrey Lake | Other |
| Directing | Shannon Wilson | Second Assistant Director |
| Art | John Hammer Maxwell | Set Dresser |
| Directing | Mic Rodgers | Second Unit Director |
| Art | Brad Curry | Other |
| Visual Effects | Janek Sirrs | Visual Effects |
