Vier onbekende mensen stappen op een avond in San Francisco nietsvermoedend in de bus. De buschauffeur wordt echter op zeer prettige wijze afgeleid en zij verongelukken allen. Tegelijkertijd wordt tijdens het ongeluk in een van de betrokken auto's Thomas geboren. En juist deze onwillige sterveling is voorbestemd om de onvervulde dromen van de vier ongelukkige zielen te doen uitkomen.
Nee, helaas is Heart and Souls nog niet beschikbaar op Netflix in Nederland.
| Sound | Marc Shaiman | Original Music Composer |
| Directing | Ron Underwood | Director |
| Writing | Brent Maddock | Screenplay |
| Editing | O. Nicholas Brown | Editor |
| Camera | Michael W. Watkins | Director of Photography |
| Production | Sean Daniel | Producer |
| Production | Nancy Roberts | Producer |
| Crew | Mic Rodgers | Stunt Coordinator |
| Crew | Michael Runyard | Stunts |
| Crew | Sonja Davis | Stunts |
| Crew | Adam Shankman | Choreographer |
| Crew | John C. Meier | Stunts |
| Visual Effects | Tom Martinek | I/O Supervisor |
| Writing | Brent Maddock | Screenstory |
| Production | Dirk Petersmann | Line Producer |
| Writing | S.S. Wilson | Screenplay |
| Art | Anne H. Ahrens | Set Decoration |
| Writing | Gregory Hansen | Screenstory |
| Production | Dixie J. Capp | Associate Producer |
| Art | John Muto | Production Design |
| Costume & Make-Up | Ken Chase | Key Makeup Artist |
| Production | Pam Dixon | Casting |
| Writing | S.S. Wilson | Screenstory |
| Writing | Erik Hansen | Screenstory |
| Writing | Gregory Hansen | Screenplay |
| Costume & Make-Up | Dione Taylor | Key Hair Stylist |
| Production | James Jacks | Executive Producer |
| Art | Dan Webster | Art Direction |
| Costume & Make-Up | JoAnn Stafford-Chaney | Hairstylist |
| Writing | Erik Hansen | Screenplay |
| Production | Gregory Hansen | Co-Producer |
| Costume & Make-Up | Karen Bradley | Makeup Artist |
| Production | Cari-Esta Albert | Executive Producer |
| Costume & Make-Up | James R. Scribner | Makeup Artist |
| Production | Erik Hansen | Co-Producer |
| Costume & Make-Up | Jean-Pierre Dorléac | Costume Design |
| Directing | Mic Rodgers | Second Unit Director |
| Art | Gary Gagliardo | Construction Foreman |
| Directing | Daniel Silverberg | Second Assistant Director |
| Art | Mike Helbig | Set Dresser |
| Art | Danny Hinzo | Painter |
| Directing | Polly Ann Mattson | Second Second Assistant Director |
| Art | Lori Harrison | Set Dresser |
| Production | Dirk Petersmann | Unit Production Manager |
| Directing | Pamela S. Kuri | Second Second Assistant Director |
| Directing | Shannon Wilson | Second Assistant Director |
| Art | Brad Curry | Other |
| Art | Horst Grandt | Property Master |
| Art | Kristin Argue | Other |
| Art | Hugo Herrera | Greensman |
| Directing | Yudi Bennett | First Assistant Director |
| Art | Amy Feldman | Other |
| Art | Ross Harpold | Set Dresser |
| Crew | John Bullard | Propmaker |
| Directing | Shawn Hanley | Other |
| Art | John Alvin | Other |
| Art | Steven Lane Ewing | Other |
| Art | John Berger | Set Designer |
| Art | Gary Heider | Other |
| Crew | David Castro, Jr. | Other |
| Art | James Holden | Set Dresser |
| Art | Bill Jackson | Art Department Coordinator |
| Art | Chris H. Kelly | Construction Foreman |
| Art | Douglas E. Maxwell | Leadman |
| Art | Robert L. King | Other |
| Art | Dean B. Katz | Set Dresser |
| Art | John H. Maxwell | Set Dresser |
| Art | John Moore | Other |
| Crew | Allan Johnson | Other |
| Crew | Leopold Mouneau, Jr. | Other |
| Art | John M. Holliday | Construction Foreman |
| Art | Geoffrey Lake | Other |
| Visual Effects | Janek Sirrs | Visual Effects |
