Nadat Alice op het nippertje kon ontsnappen uit het ondergrondse Umbrella laboratorium The Hive, werd ze opgepakt. Nu ontwaakt ze in een ziekenhuis en slaagt erin te ontsnappen. Ze bevindt zich in het verwoeste Raccoon City, waar ze het samen met een groepje overlevenden, waaronder agente Jill Valentine en huurling Carlos Olivera, moet opnemen tegen het gruwelijke kwaad dat daar rondzwerft. Dit keer zijn zombies niet het enige, want er zwerft nog iets veel gruwelijkers door de straten van Raccoon City: de Nemesis, een vreselijk monster dat alles op z'n weg wil vernietigen.
Nee, helaas is Resident Evil: Apocalypse nog niet beschikbaar op Netflix in Nederland.
| Production | Samuel Hadida | Executive Producer |
| Production | Paul W. S. Anderson | Producer |
| Production | Victor Hadida | Executive Producer |
| Production | Bernd Eichinger | Executive Producer |
| Production | Don Carmody | Producer |
| Production | Dennis Chapman | Line Producer |
| Production | Robert Kulzer | Executive Producer |
| Directing | Alexander Witt | Director |
| Production | Jeremy Bolt | Producer |
| Crew | Maxine Dumont | Stunts |
| Crew | Alicia Turner | Stunts |
| Crew | Cheryl Quiacos | Stunts |
| Crew | Kym Kristalie | Stunts |
| Crew | Stéphane Lefebvre | Stunts |
| Crew | Taryn Ash | Stunts |
| Crew | Isolde O'Neill | Stunts |
| Crew | Monique Ganderton | Stunts |
| Crew | Sue Parker | Stunts |
| Crew | Janet Morin | Stunts |
| Crew | Joanne Leach | Stunts |
| Crew | Vanessa Reid | Stunts |
| Crew | Patrizia Quas | Stunts |
| Crew | Catherine Gourdier | Stunts |
| Crew | Mary Ann Stevens | Stunts |
| Crew | Megan Fahlenbock | Stunts |
| Crew | Melissa R. Stubbs | Stunts |
| Costume & Make-Up | Mary E. McLeod | Costume Design |
| Production | Tina Gerussi | Casting |
| Production | 小林裕幸 | Associate Producer |
| Sound | Jeff Danna | Original Music Composer |
| Editing | Eddie Hamilton | Editor |
| Production | Daniel S. Kletzky | Associate Producer |
| Production | Martin Moszkowicz | Executive Producer |
| Writing | Paul W. S. Anderson | Writer |
| Camera | Nick Bacon | Best Boy Grip |
| Crew | Steve Lucescu | Stunt Coordinator |
| Art | Nigel Churcher | Art Direction |
| Art | Stephen Paisley | Painter |
| Art | Martin L. Mercer | Sculptor |
| Art | Kirk Cheney | Construction Coordinator |
| Crew | Elia Cmiral | Additional Music |
| Crew | John Coles | Driver |
| Crew | Rick Leary | Sequence Supervisor |
| Art | Paul D. Austerberry | Production Design |
| Art | Mayumi Konishi-Valentine | Set Designer |
| Crew | Shawney Cohen | CG Supervisor |
| Crew | Sharon Moore | Choreographer |
| Camera | Derek Rogers | Director of Photography |
| Crew | Julie Adams | Dialect Coach |
| Crew | Gregor Hutchison | Post Production Supervisor |
| Costume & Make-Up | Teresa Buccione | Key Hair Stylist |
| Crew | Charles Taylor | Armorer |
| Art | Steven Essam | Set Decoration |
| Camera | Rolf Konow | Still Photographer |
| Art | Philip Spurvey | Location Scout |
| Art | Fabian Jonathan | Art Direction |
| Camera | Christian Sebaldt | Director of Photography |
| Crew | Matthew Lammerich | Scenic Artist |
| Art | David G. Fremlin | Assistant Art Director |
| Crew | John Jay Hebert | Second Unit Cinematographer |
| Crew | Dave Axford | Makeup Effects |
| Crew | Nick Alachiotis | Stunts |
| Camera | Tony Magaletta | First Assistant Camera |
| Crew | Simone Lindo | Craft Service |
| Crew | Steve Holt | Set Medic |
| Camera | Roberto W. Contreras D. | Camera Operator |
| Camera | Sean Jensen | Steadicam Operator |
| Crew | Kyle Menzies | Digital Effects Supervisor |
| Crew | Vladimir Popovic | Systems Administrators & Support |
| Production | Kimberley Bradley | Production Coordinator |
| Lighting | Kevin Alanthwaite | Gaffer |
| Lighting | Alex Murtaza | Lighting Artist |
| Sound | Craig Henighan | Supervising Sound Editor |
| Sound | Tony Lewis | Music Editor |
| Writing | Rob McCallum | Storyboard |
| Sound | Todd Beckett | Sound Re-Recording Mixer |
| Directing | Carol Pears | Script Supervisor |
| Crew | Sue Len Quon | Visual Effects Editor |
| Directing | Alan Goluboff | Assistant Director |
| Visual Effects | Sarah McMurdo | Visual Effects Coordinator |
| Crew | Anthony Nocera | Video Assist Operator |
| Sound | Liz Gallacher | Music Supervisor |
| Sound | Kevin Banks | Sound Editor |
| Lighting | Tracy Shaw | Rigging Grip |
| Lighting | Kevin Barnes | Electrician |
| Sound | Alex Bullick | First Assistant Sound Editor |
| Sound | Nathan Robitaille | Sound Effects Editor |
| Editing | Claire McGrane | Digital Intermediate |
| Production | Chris Ellefson | Researcher |
| Visual Effects | Steve Parsons | Visual Effects |
| Production | Jonathan Matthews | Location Manager |
| Sound | Denis Bellingham | Boom Operator |
| Sound | Nicholas Dodd | Orchestrator |
| Sound | Craig Henighan | Sound Designer |
| Visual Effects | Mark Halsall | Visual Effects Producer |
| Crew | Joel Harris | Utility Stunts |
| Lighting | John O'Boyle | Best Boy Electric |
| Visual Effects | Barb Benoit | Digital Compositors |
| Crew | John Charles | Software Engineer |
| Lighting | Ian Foulds | Rigging Gaffer |
| Production | Nan Skiba | Production Manager |
| Visual Effects | Dennis Berardi | Visual Effects Supervisor |
| Crew | Jean Frenette | Stunts |
| Production | Darron Leiren-Young | Assistant Production Coordinator |
| Visual Effects | Brian Anderson | 3D Animator |
| Costume & Make-Up | Madeline Brian | Costume Illustrator |
| Sound | Russ Miller | Musician |
| Camera | Thomas Care | Dolly Grip |
| Crew | Tom Blacklock | Pyrotechnician |
| Directing | Pierre Henry | First Assistant Director |
| Directing | Cameron Kuc | Third Assistant Director |
| Editing | Tom Mayclim | Negative Cutter |
| Production | Ian Maxwell | Assistant Production Manager |
| Production | Robyn Ray | Casting Consultant |
| Sound | Jeff Danna | Music Score Producer |
| Visual Effects | Emily Cobb | 3D Modeller |
| Art | Nick Fischer | Set Dresser |
| Costume & Make-Up | Adam Smith | Key Costumer |
| Directing | Grant Lucibello | Second Assistant Director |
| Sound | Stephen Barden | ADR Editor |
| Camera | Clyde Miller | Aerial Camera |
| Camera | Renée Pilgrim | Camera Loader |
| Crew | Shelley Cook | Aerial Coordinator |
| Crew | Guillaume Carpentier | Pilot |
| Camera | Monty Montgomerie | Key Grip |
| Writing | Monica Sandstede | Story Editor |
| Art | Glyn Tebbutt | Title Designer |
| Camera | Randy Burbidge | Grip |
| Costume & Make-Up | Marie Nardella | Key Makeup Artist |
| Production | Roberta Romano | Casting Assistant |
| Costume & Make-Up | Paul Jones | Makeup Effects Designer |
| Visual Effects | Mark Palowich | CG Animator |
| Visual Effects | Conrad Dueck | 3D Supervisor |
| Visual Effects | Jean-Louis Billard | 3D Artist |
| Crew | Branko Racki | Stunts |
| Crew | Greg O'Hara | Transportation Coordinator |
| Crew | Joel Green | Unit Publicist |
| Directing | Spiro Razatos | Second Unit Director |
| Production | Lorraine Samuel | Post Production Coordinator |
| Sound | Nicholas Dodd | Conductor |
| Costume & Make-Up | Lorraine Greenwood | Assistant Makeup Artist |
| Costume & Make-Up | Elayne Alexander | Costume Set Supervisor |
| Sound | Matthew McKenzie | ADR Recordist |
| Crew | Rocco Larizza | Special Effects Assistant |
| Editing | Adam Glasman | Colorist |
| Crew | Jennifer Wood | Visual Effects Editor |
| Camera | Murat Akser | Assistant Camera |
| Visual Effects | Barb Benoit | Visual Effects Compositor |
| Art | Temple Clark | Storyboard Artist |
| Camera | Craig Cooper | Clapper Loader |
| Production | Drazen Baric | Assistant Location Manager |
| Production | Ann Fitzgerald | Accountant |
| Sound | Adam Sharpe | ADR Mixer |
| Sound | Gina Gyles | Assistant Foley Artist |
| Art | Matt Middleton | Second Assistant Art Director |
| Production | Fernando DaSilva | Location Production Assistant |
| Directing | Liza Vespi | Continuity |
| Sound | Steve Baine | Foley Artist |
| Art | Monica Wier | Set Supervisor |
| Crew | Joel Crimi | Special Effects Technician |
| Visual Effects | Patrick White | Visual Effects Production Assistant |
| Camera | Deanna Cadette | Second Assistant Camera |
| Art | Ian Fraser | Head Carpenter |
| Visual Effects | Carl Beyer | Visual Effects Production Manager |
| Art | Barton Rendulic | Concept Artist |
| Sound | Peter Persaud | Foley Recordist |
| Sound | Rose Gregoris | Second Assistant Sound |
| Crew | Miriam Laurence | Dialogue Coach |
| Production | Tami Thomson | Travel Coordinator |
| Production | Anthony Valenti | Assistant Accountant |
| Production | Dylaine Bovaird | Extras Casting Assistant |
| Visual Effects | Jody Johnson | Digital Compositor |
| Crew | Paul Marshall | Head Driver |
| Crew | Skyler Wilson | Key Special Effects |
| Production | Hope White | First Assistant Accountant |
| Production | Jillian Sabean | Production Secretary |
| Visual Effects | Noel Hooper | Compositing Supervisor |
| Production | Jane Rogers | Extras Casting |
| Production | James F. Breithaupt | Key Accountant |
| Visual Effects | Karl Sisson | CG Artist |
| Crew | Kris Wood | Playback Coordinator |
| Production | Baron Evans | Assistant Production Coordinator |
| Lighting | Pete Daprato | Key Rigging Grip |
| Crew | Derek Aasland | Choreographer |
| Production | David McElroy | Production Assistant |
| Production | Jan Hogevold | Production Executive |
| Sound | Jack Stew | Foley Artist |
| Costume & Make-Up | Marie Nardella | Makeup Artist |
| Directing | Walter Lawlor | Assistant Director Trainee |
| Crew | Danny Lima | Stunts |
