Henry Roth werkt bij een groot aquarium-complex in Hawaii. Hij wordt verliefd op Lucy, een meisje dat aan korte termijn-geheugenverlies lijdt. Om een relatie met haar aan te knopen moet Henry dus elke keer opnieuw zijn best doen zodat Lucy weer verliefd op hem wordt.
Nee, helaas is 50 First Dates nog niet beschikbaar op Netflix in Nederland.
| Directing | Peter Segal | Director |
| Writing | George Wing | Screenplay |
| Camera | Jack N. Green | Director of Photography |
| Editing | Jeff Gourson | Editor |
| Art | Alex Hillkurtz | Storyboard Artist |
| Production | Scott Bankston | Co-Producer |
| Production | Michael Ewing | Executive Producer |
| Production | Jack Giarraputo | Producer |
| Production | Steve Golin | Producer |
| Production | Kevin Grady | Associate Producer |
| Production | Nancy Juvonen | Producer |
| Production | Larry Kennar | Co-Producer |
| Production | Daniel Lupi | Executive Producer |
| Production | Jay Roach | Executive Producer |
| Camera | Darren Michaels | Still Photographer |
| Sound | Teddy Castellucci | Original Music Composer |
| Costume & Make-Up | Ellen Lutter | Costume Design |
| Sound | Michael Dilbeck | Music Supervisor |
| Costume & Make-Up | Robert Q. Mathews | Costume Supervisor |
| Crew | Webster Whinery | Stunt Coordinator |
| Art | Alan Au | Production Design |
| Production | Roger Mussenden | Casting |
| Art | Domenic Silvestri | Art Direction |
| Art | Robert Greenfield | Set Decoration |
| Directing | Nancy Karlin | Script Supervisor |
| Camera | Stephen S. Campanelli | Camera Operator |
| Camera | Bill Coe | First Assistant Camera |
| Costume & Make-Up | Jeannie H. Kelly | Assistant Costume Designer |
| Costume & Make-Up | Rose Librizzi | Makeup Department Head |
| Costume & Make-Up | Nancy Tong | Hair Department Head |
| Costume & Make-Up | Lona Vigi | Hairstylist |
| Costume & Make-Up | Ann Pala | Makeup Artist |
| Costume & Make-Up | Pauletta O. Lewis | Key Hair Stylist |
| Costume & Make-Up | Robin Fredriksz | Makeup Artist |
| Sound | David Kelson | Production Sound Mixer |
| Production | Will Weiske | Production Supervisor |
| Production | Susan Ehrhart | Production Coordinator |
| Art | Donald B. Woodruff | Assistant Art Director |
| Production | Elizabeth Boykewich | Casting Associate |
| Sound | Elmo Weber | Supervising Sound Editor |
| Sound | Derek Vanderhorst | Supervising Sound Effects Editor |
| Sound | Orada Jusatayanond | Sound Effects Editor |
| Sound | Cameron Steenhagen | Sound Effects Editor |
| Sound | J.J. George | Music Editor |
| Sound | Stuart Grusin | Music Editor |
| Visual Effects | Sheena Duggal | Visual Effects Supervisor |
| Visual Effects | Victoria Alonso | Visual Effects Producer |
| Art | Dru Homer | Art Department Coordinator |
| Art | Karen Higgins | Construction Coordinator |
| Art | Bob Skemp | Greensman |
| Art | Mark Weissenfluh | Leadman |
| Art | Scott Trimble | Location Scout |
| Art | David Carberry | Painter |
| Art | Gregory S. Hooper | Set Designer |
| Art | Bill 'Kauhane' Hoyt | Standby Painter |
| Camera | Rick Crum | Grip |
| Costume & Make-Up | Laurel Frushour | Set Costumer |
| Crew | Bruce Richter | Carpenter |
| Crew | Sandy Reed | Craft Service |
| Crew | Bruce Comtois | Driver |
| Crew | Richard Robinson | Propmaker |
| Crew | Dave Moorer | Set Medic |
| Crew | Kirk Huston | Transportation Captain |
| Crew | Geno Hart | Transportation Coordinator |
| Crew | Spooky Stevens | Unit Publicist |
| Crew | Alfred Ainsworth Jr. | Video Assist Operator |
| Crew | Steve Rhee | Visual Effects Editor |
| Editing | Dan Muscarella | Color Timer |
| Lighting | Justin Duval | Electrician |
| Lighting | Mike Macias | Lighting Technician |
| Lighting | T. Daniel Scaringi | Rigging Grip |
| Production | Megan Mathews | Production Accountant |
| Sound | Robert Jackson | Boom Operator |
| Visual Effects | Eddie Soria | Visual Effects Coordinator |
| Art | Nicole Nakamoto | Art Department Assistant |
| Camera | David Gasperik | Additional Camera |
| Costume & Make-Up | Clare Hallworth | Assistant Costume Designer |
| Crew | James D. Bissell | Second Unit |
| Crew | John Charles | Software Engineer |
| Crew | Skip Kimball | Telecine Colorist |
| Crew | Reid Paul | Digital Effects Supervisor |
| Sound | Pete Anthony | Orchestrator |
| Production | Daniel Lupi | Unit Production Manager |
| Crew | Crystal Michelle | Stunts |
| Art | John Puglisi | Conceptual Illustrator |
| Art | Oscar Delgadillo | Set Dresser |
| Art | Thomas Cobb | Title Designer |
| Camera | Hans Bjerno | Aerial Director of Photography |
| Camera | Shayna Ritenour | Camera Loader |
| Camera | James D. Wickman | Dolly Grip |
| Camera | Charles Saldaña | Key Grip |
| Costume & Make-Up | Carme Tenuta | Key Makeup Artist |
| Directing | Adam Druxman | First Assistant Director |
| Directing | Joseph J. Kontra | Second Assistant Director |
| Editing | Mo Henry | Negative Cutter |
| Production | Demelza Cronin | Assistant Production Coordinator |
| Production | Kendra Carter | Casting Assistant |
| Sound | Russell Farmarco | ADR Editor |
| Sound | David Bach | ADR Supervisor |
| Sound | Drake Jenevein | Assistant Sound Editor |
| Sound | Marc Glassman | Foley Editor |
| Sound | Mike Deasy | Musician |
| Sound | Daniel Brock | Utility Sound |
| Sound | Robert Jackson | Dialogue Editor |
| Art | Timothy S. Wiles | Property Master |
| Sound | Sean Landeros | Sound Recordist |
| Crew | Michael Adams | Stunts |
| Crew | Katie Wright Pere | Stunts |
| Crew | Paul Eliopoulos | Stunts |
| Crew | Michael T. Brady | Stunts |
| Crew | Gary Guercio | Stunts |
| Art | Chuck Askerneese | Assistant Property Master |
| Camera | Bill Marti | Second Assistant "B" Camera |
| Camera | Bobby McMahan | Second Assistant Camera |
| Costume & Make-Up | Mari Grimaud | Key Costumer |
| Crew | Karen Jine | Production Office Assistant |
| Crew | Jerry Miscevich | Special Effects |
| Crew | Lisa Marie Boiko | Stand In |
| Editing | Tom Costain | Additional Editing |
| Editing | Laura Weiss | Assistant Editor |
| Lighting | H. Mark Vuille | Chief Lighting Technician |
| Production | Rodney Brown Alamo | Location Assistant |
| Production | Tim Hillman | Location Manager |
| Visual Effects | Steven Fagerquist | Visual Effects |
| Visual Effects | Christopher Nibley | VFX Director of Photography |
| Costume & Make-Up | John Hammer Maxwell | On Set Dresser |
| Art | Jamie Rama | Production Illustrator |
| Production | Mady Manson Burza | Post Production Accountant |
| Crew | Bonnie Kanner | Executive Visual Effects Producer |
| Camera | Douglas Olivares | "B" Camera Operator |
| Crew | Adam Pinkstaff | Transportation Co-Captain |
| Crew | Stan Sandler | In Memory Of |
| Crew | Joe Stevano | Systems Administrators & Support |
| Sound | Dennis Sands | Scoring Mixer |
| Costume & Make-Up | Anthony Franco | Costumer |
| Directing | Matthew D. Smith | Additional Second Assistant Director |
| Directing | Timothy Grant Engle | Second Second Assistant Director |
| Directing | Jim Bissell | Second Unit Director |
| Art | Ricky Johnson | Construction Grip |
| Art | Martin Charles | Graphic Designer |
| Art | Chris Samp | Set Painter |
| Art | P.K. MacCarthy | Storyboard Artist |
| Sound | Howard Carle | ADR Mixer |
| Sound | Howard London | ADR Recordist |
| Sound | Vincent Guisetti | Foley Artist |
| Sound | Kyle Rochlin | Foley Mixer |
| Crew | Roger Kelton | Special Effects Technician |
| Visual Effects | Todd Mesher | Visual Effects Compositor |
| Crew | Brycen Counts | Stunt Double |
| Crew | Adam Pinkstaff | Stunt Driver |
| Camera | Matthew Berner | Assistant Camera |
| Editing | Greg Curry | Colorist |
| Editing | Paul McGhee | Digital Color Timer |
| Production | Claudia Bestor | Assistant Location Manager |
| Production | Steven Butensky | Assistant Accountant |
| Lighting | Michael K. O'Melia | Assistant Chief Lighting Technician |
| Visual Effects | Christian Boudman | Digital Compositor |
| Production | Brad Kenny | Extras Casting |
| Production | Mele K.T. Locey | Extras Casting Assistant |
| Lighting | T. Daniel Scaringi | Key Rigging Grip |
| Production | Michael Roccuzzo | Payroll Accountant |
| Production | Scott Berrie | Production Assistant |
| Production | Kerri Smeltzer | Production Secretary |
| Visual Effects | Lea Lambert | Rotoscoping Artist |
| Production | Kenny Gallagher | Second Assistant Accountant |
| Production | Georgina Marquis | Travel Coordinator |
| Crew | Trevor Carroll-Coe | Loader |
| Crew | Cliff Fleming | Pilot |
