Agent Charlie leeft een voorbeeldig leven. Als State Trooper probeert hij de vrede binnen de gemeenschap te bewaren. Wat er ook rondom hem gebeurt, hij verheft nooit zijn stem. Kortom, hij is eigenlijk veel te goed voor deze wereld. Ook wanneer zijn vrouw hem op een dag brutaal verlaat, geeft Charlie geen krimp. Maar op een dag gebeurt er iets vreemds met hem. Plots lijdt hij aan een gespleten persoonlijkheid.
Nee, helaas is Me, Myself & Irene nog niet beschikbaar op Netflix in Nederland.
| Directing | Peter Farrelly | Director |
| Production | Rick Montgomery | Casting |
| Editing | Christopher Greenbury | Editor |
| Directing | Bobby Farrelly | Director |
| Production | Peter Farrelly | Producer |
| Production | Bradley Thomas | Producer |
| Sound | Lee Scott | Original Music Composer |
| Writing | Peter Farrelly | Screenplay |
| Writing | Bobby Farrelly | Screenplay |
| Costume & Make-Up | Pamela Withers | Costume Design |
| Camera | Mark Irwin | Director of Photography |
| Production | Bobby Farrelly | Producer |
| Writing | Mike Cerrone | Screenplay |
| Crew | Paul Salamoff | Makeup Effects |
| Production | Patrick Healy | Associate Producer |
| Sound | Pete Yorn | Original Music Composer |
| Production | Marc S. Fischer | Co-Producer |
| Production | Clemens E. Franek | Associate Producer |
| Production | Tom Schulman | Executive Producer |
| Production | Mark Charpentier | Co-Producer |
| Production | Charles B. Wessler | Executive Producer |
| Production | Linda Fields Hill | Associate Producer |
| Production | J.B. Rogers | Co-Producer |
| Crew | Corey Michael Eubanks | Stunts |
| Production | Kris Meyer | Associate Producer |
| Camera | Jeffrey N. Civa | First Assistant Camera |
| Art | Arlan Jay Vetter | Art Direction |
| Art | Richard Fojo | Set Designer |
| Camera | Stan McClain | Camera Operator |
| Art | Robert Kopp | Greensman |
| Art | Christopher J. Noonan | Construction Foreman |
| Art | Scott Jacobson | Set Decoration |
| Art | Seth Blackman | Location Scout |
| Art | Michael Budge | Assistant Art Director |
| Art | Michael Metzel | Construction Coordinator |
| Camera | Eric J. Goldstein | Additional Photography |
| Art | Manya Cetlin | Art Department Coordinator |
| Art | Sydney J. Bartholomew Jr. | Production Design |
| Camera | Bubba Sheffield | Key Grip |
| Costume & Make-Up | Ardis Cohen | Key Hair Stylist |
| Crew | Nichole Hiltz | Stand In |
| Camera | Glenn Watson | Still Photographer |
| Crew | Steven Butcher | Picture Car Coordinator |
| Crew | Dan Carter | Projection |
| Art | Richard K. Wright | Property Master |
| Costume & Make-Up | William Bonn | Set Dressing Artist |
| Costume & Make-Up | Virginia Burton | Costume Supervisor |
| Costume & Make-Up | Bernadette Mazur | Makeup Artist |
| Sound | Andrea Eliseyan | Sound Recordist |
| Costume & Make-Up | Janice Alexander | Hairstylist |
| Costume & Make-Up | Clinton Wayne | Prosthetic Makeup Artist |
| Camera | John S. Moyer | Steadicam Operator |
| Crew | Robert Martini | Transportation Captain |
| Crew | Marc H. Katz | Craft Service |
| Lighting | Jay W. Yowler | Gaffer |
| Crew | Jim Beinke | Animatronic and Prosthetic Effects |
| Lighting | Jenn Mears | Rigging Grip |
| Production | Harvey Malkin | Production Accountant |
| Sound | Manish Raval | Music Supervisor |
| Sound | Jonathon 'Earl' Stein | Sound Mixer |
| Crew | Stephen DeBoer | Propmaker |
| Crew | James 'Sporty' Ahern | Set Production Assistant |
| Lighting | Samantha Bahramian | Electrician |
| Sound | Andy Kopetzky | Sound Editor |
| Crew | Ernie Malik | Unit Publicist |
| Directing | Hal Olofsson | Assistant Director |
| Lighting | Troy White | Best Boy Electric |
| Sound | Brian Bulman | Music Editor |
| Crew | Kenneth D. Fitzgibbon | Set Medic |
| Production | Thomas A. Imperato | Executive In Charge Of Production |
| Editing | Larry Madaras | First Assistant Editor |
| Lighting | Troy White | Best Boy Electric |
| Production | Melissa Stanley Cohen | Production Coordinator |
| Visual Effects | Allison Troxell | Visual Effects Producer |
| Visual Effects | Constance Bracewell | Visual Effects Supervisor |
| Crew | Patrice Courtaut | Chef |
| Crew | Denise Avallon | Driver |
| Editing | Sean Madaras | Editorial Production Assistant |
| Crew | Rand Angelicola | Scenic Artist |
| Crew | Dotan Bonen | Security |
| Production | Garrett Grant | Unit Production Manager |
| Sound | Ted Caplan | Sound Effects Editor |
| Sound | Jon Udell | Boom Operator |
| Sound | Vanessa Lapato | Supervising Sound Editor |
| Crew | Jonathan Askew | Carpenter |
| Crew | William Olofsson | Loader |
| Sound | Douglas Hinton | Assistant Sound Editor |
| Camera | Michael Ferris | Underwater Camera |
| Costume & Make-Up | Jennifer Dozier | Set Costumer |
| Crew | P. Todd Coe | Post Production Supervisor |
| Crew | Rick Barker | Stunt Coordinator |
| Sound | Dawn Fintor | Foley |
| Lighting | Lon Caracappa | Rigging Gaffer |
| Crew | James P. Whalen | Transportation Coordinator |
| Production | Michael G. Miller | Casting Associate |
| Production | Eric Hedayat | Location Manager |
| Crew | Walt Vincent | Score Engineer |
| Costume & Make-Up | Ann Powderly | Seamstress |
| Crew | Robert Vazquez | Special Effects Coordinator |
| Editing | Dennis McNeill | Color Timer |
| Crew | Joey Box | Stunts |
| Crew | Barbara Anne Klein | Stunts |
| Crew | Mark De Alessandro | Stunts |
| Production | Hank Chilton | Production Supervisor |
| Crew | Denney Pierce | Stunts |
| Crew | Gilbert B. Combs | Stunts |
| Crew | Michael Cassidy | Stunts |
| Sound | Derek Casari | ADR Engineer |
| Sound | Skip Longfellow | Sound Assistant |
| Camera | Jerry Bertolami | Dolly Grip |
| Production | Liza-Anne Cabral | Travel Coordinator |
| Directing | Greg Guzik | Additional Second Assistant Director |
| Directing | Ingrid K. Behrens | Second Second Assistant Director |
| Art | Chelsea Heneise | Title Designer |
| Production | Kori Shadrick | Location Coordinator |
| Production | Denise Rosen | First Assistant Accountant |
| Sound | David Lucarelli | ADR Recordist |
| Sound | Steve F. Price | First Assistant Sound Editor |
| Camera | James J. Callahan | Best Boy Grip |
| Camera | Egor Davidoff | Second Assistant Camera |
| Production | Karen Preus | Location Assistant |
| Sound | Lee Scott | Supervising Music Editor |
| Sound | Dawn Fintor | Foley Artist |
| Production | Kevin Fennessy | Extras Casting |
| Sound | David Betancourt | Foley Mixer |
| Production | Michael DeSantis | Second Assistant Accountant |
| Costume & Make-Up | Tony Gardner | Makeup Effects Designer |
| Production | Angela Randazzo | Payroll Accountant |
| Art | Lorne Grant | Assistant Property Master |
| Sound | Charleen Richards-Steeves | ADR Mixer |
| Production | Samantha Bass | Art Department Production Assistant |
| Production | Dianne Bellino | Assistant Production Coordinator |
| Production | Ann Christman | Production Secretary |
| Costume & Make-Up | Felice Diamond | Assistant Makeup Artist |
| Camera | Matt Irwin | Camera Trainee |
| Production | Jennifer Battista | Production Assistant |
| Crew | Pat Banta | Stunt Double |
| Visual Effects | Jamie Dixon | Lead Animator |
| Production | Nadia Randazzo Bombino | Assistant Accountant |
| Production | Maria Celeste Arruda III | Extras Casting Assistant |
| Crew | Brandon Trost | Special Effects Assistant |
| Production | Pam Jack | Assistant Location Manager |
| Crew | Susan Humphrey | Animal Wrangler |
| Costume & Make-Up | Denverly Grant | Key Set Costumer |
| Directing | Josh Klausner | Second Unit Director |
| Crew | Andrew Campbell | Special Effects Technician |
| Editing | Gary Burritt | Negative Cutter |
| Crew | Patricia M. Peters | Stunts |
| Crew | John-Clay Scott | Stunts |
| Crew | Kurt Beckler | Assistant Craft Service |
| Sound | Alison Fisher | Dialogue Editor |
| Crew | Phil Culotta | Stunts |
| Crew | Clint Lilley | Stunts |
