Charlie Fineman en Alan Johnson zijn oud-studiegenoten die het contact met elkaar verloren hebben. Ze lopen elkaar toevallig tegen het lijf in Manhattan en de vriendschap is snel weer opgepakt.
Nee, helaas is Reign Over Me nog niet beschikbaar op Netflix in Nederland.
| Directing | Mike Binder | Director |
| Production | Jack Giarraputo | Executive Producer |
| Production | Lynwood Spinks | Executive Producer |
| Editing | Steve Edwards | Editor |
| Editing | Jeremy Roush | Editor |
| Camera | Russ T. Alsobrook | Director of Photography |
| Writing | Mike Binder | Screenplay |
| Costume & Make-Up | Deborah L. Scott | Costume Design |
| Crew | Jennifer Lamb | Stunts |
| Art | Greg Berry | Art Direction |
| Art | Jon Danniells | Set Decoration |
| Costume & Make-Up | Ann Pala | Makeup Department Head |
| Sound | Marc Glassman | Sound Effects Editor |
| Sound | David Bach | Supervising Sound Editor |
| Sound | Elmo Weber | Supervising Sound Editor |
| Sound | Elmo Weber | Sound Re-Recording Mixer |
| Sound | Cameron Steenhagen | Dialogue Editor |
| Costume & Make-Up | Gary Archer | Prosthetics |
| Sound | Dave Jordan | Music Supervisor |
| Sound | Rolfe Kent | Original Music Composer |
| Production | Jack Binder | Producer |
| Production | Michael Rotenberg | Producer |
| Art | Christian Wintter | Production Design |
| Production | Sharon Bialy | Casting |
| Directing | Nancy Karlin | Script Supervisor |
| Art | David Swayze | Art Direction |
| Crew | Joanne Lamstein | Stunts |
| Crew | John Cenatiempo | Stunt Driver |
| Crew | Roy Farfel | Stunt Driver |
