Tien jaar na de avonturen in American Pie, ontdekt een stel nieuwe leerlingen van East Great Falls High hun 'Bijbel', verborgen in de bibliotheek. Het probleem is echter dat het boek beschadigd is door één van die leerlingen. Ze nemen contact op met Noah Levenstein (Eugene Levy), die samen met de jongens probeert om de verhalen in de Bijbel weer terug te krijgen.
Nee, helaas is American Pie Presents: The Book of Love nog niet beschikbaar op Netflix in Nederland.
| Directing | John Putch | Director |
| Writing | David H. Steinberg | Writer |
| Writing | Adam Herz | Characters |
| Editing | John Gilbert | Editor |
| Production | Jan Glaser | Casting |
| Sound | David Lawrence | Original Music Composer |
| Sound | Paul DiFranco | Music Supervisor |
| Production | Stuart Aikins | Casting |
| Production | Sean Cossey | Casting |
| Directing | Allan Harmon | First Assistant Director |
| Production | Simon Abbott | Unit Production Manager |
| Directing | Victor Landrie | Second Assistant Director |
| Crew | Ernie Jackson | Stunt Coordinator |
| Crew | Brett Armstrong | Stunt Double |
| Camera | Laura Hyvarinen | Second Assistant "B" Camera |
| Camera | Toby Armitt | First Assistant Camera |
| Crew | Krista Bell | Stunt Double |
| Costume & Make-Up | Deb Schrieber | Costumer |
| Directing | Marijke Richman | Assistant Director |
| Sound | Peter D. Lago | Sound Effects Editor |
| Sound | Adrian van Velsen | Music Editor |
| Production | James Fantin | Assistant Production Coordinator |
| Camera | Danny Nowak | Camera Operator |
| Sound | Adam DeCoster | Foley Artist |
| Directing | Alexandra La Roche | Script Supervisor |
| Sound | Kristian Bailey | Sound Assistant |
| Production | Stacy A. Harris | Production Coordinator |
| Sound | Brian S.M. Wroth | ADR Editor |
| Visual Effects | Chris Bremble | Visual Effects Producer |
| Crew | Yves Cameron | Stunt Coordinator |
| Camera | Lou Gruzelier | Steadicam Operator |
| Sound | Chris Higgins | Sound Assistant |
| Art | Bobbi Allyn | Assistant Set Decoration |
| Directing | Victor Landrie | Second Unit First Assistant Director |
| Sound | Kelly Vandever | Sound Re-Recording Mixer |
| Sound | Greg Mauer | Foley Mixer |
| Sound | Sean Madsen | Sound Engineer |
| Camera | Mark Weinhaupl | Second Assistant "A" Camera |
| Sound | Chris Glyn-Jones | Boom Operator |
| Costume & Make-Up | Allison Chretien | Costumer |
| Costume & Make-Up | Issa Mills | Costumer |
| Camera | Mike Tanassee | Second Assistant Camera |
| Sound | Doug Latislaw | ADR Mixer |
| Sound | Jean-Paul DiFranco | Music Coordinator |
| Sound | Michael Williamson | Sound Mixer |
| Costume & Make-Up | Courtney McKenzie | Assistant Costume Designer |
| Costume & Make-Up | Jennifer Kipps | Key Makeup Artist |
| Sound | Patrick Giraudi | Dialogue Editor |
| Sound | Steven Utt | Sound Engineer |
| Costume & Make-Up | Joshana McMahon | Key Costumer |
| Costume & Make-Up | Dean Scheck | First Assistant Hairstylist |
| Crew | Colin Laurent-Bixler | Post Production Assistant |
| Visual Effects | Ron Simonson | Visual Effects Supervisor |
| Camera | Ivan Maldonado | Steadicam Operator |
| Costume & Make-Up | Tanya Howard | Assistant Makeup Artist |
| Costume & Make-Up | Robert A. Pandini | Hairstylist |
| Crew | Darren Marcoux | Special Effects Coordinator |
| Directing | Dezi Haddock | Assistant Director |
| Camera | Danny Nowak | Second Unit Director of Photography |
| Camera | Sacha Fassaert | First Assistant Camera |
| Camera | Chris Weiss | Second Assistant Camera |
| Sound | Alexander Pugh | Sound Effects Editor |
| Sound | Ben Whitver | ADR Mixer |
| Sound | Gordon Sproule | ADR Mixer |
| Crew | Noah Beggs | Stunt Double |
| Camera | Richard Eagan | First Assistant "A" Camera |
| Sound | Rick Bold | Boom Operator |
| Crew | Eunice Choi | Post Production Assistant |
| Sound | Patrick Giraudi | Supervising Sound Editor |
| Camera | Frederick Heartline | Camera Trainee |
| Costume & Make-Up | Joel Echallier | Special Effects Makeup Artist |
| Production | Rebecca Zoe Leigh | Casting Associate |
| Production | J.J. Ogilvy | Casting Associate |
| Camera | Ivan Maldonado | "B" Camera Operator |
| Crew | Phil Davis | Special Effects Assistant |
| Crew | Jan Kikumoto | Post Production Supervisor |
| Sound | Steven Avila | Sound Effects Editor |
| Crew | Bruce Crawford | Stunt Double |
| Editing | James G. White | Assistant Editor |
| Camera | Chris Helcermanas-Benge | Still Photographer |
| Costume & Make-Up | Issa Mills | Costumer |
| Camera | Ryan McMaster | "A" Camera Operator |
| Camera | Lou Gruzelier | "B" Camera Operator |
| Costume & Make-Up | Sabrina Kolyck | Costumer |
| Costume & Make-Up | Ines Zagoudakis | Costumer |
| Directing | Mike Elliott | Second Unit Director |
| Sound | Patrick Giraudi | Sound Re-Recording Mixer |
| Crew | Guy Bews | Stunt Coordinator |
| Camera | Jos Oman | First Assistant "B" Camera |
| Sound | Kristian Bailey | Sound Mixer |
| Costume & Make-Up | Wendy Levin | Costumer |
| Costume & Make-Up | Lyne Denomme | First Assistant Makeup Artist |
| Directing | David Heimbecker | Third Assistant Director |
| Sound | Irene Montero | Foley Editor |
| Sound | Rick Owens | Foley Artist |
| Sound | Amy Giammarco | ADR Coordinator |
| Camera | Ross Berryman | Director of Photography |
| Production | Craig Perry | Executive Producer |
| Production | Warren Zide | Executive Producer |
| Production | Greg Holstein | Associate Producer |
| Production | Mike Elliott | Producer |
| Art | Teresa Weston | Art Direction |
| Art | Jennifer Kom-Tong | Set Decoration |
| Production | Simon Abbott | Line Producer |
| Art | Tony Devenyi | Production Design |
| Costume & Make-Up | Cynthia Summers | Costume Design |
| Camera | Paul Mitchnick | Camera Operator |
| Camera | Paul Mitchnick | Second Unit Director of Photography |
