Uncle Buck wordt gevraagd als kinderoppas door zijn broer Bob want de vader van Bobs vrouw Cindy heeft een hartaanval gehad. Het klikt in het begin helemaal niet tussen Buck en Tia, de oudste van de drie kinderen. Pas na de nodige strubbelingen begint Tia te begrijpen dat alles wat Buck doet voor haar eigen bestwil is.
Nee, helaas is Uncle Buck nog niet beschikbaar op Netflix in Nederland.
| Camera | Ralf D. Bode | Director of Photography |
| Sound | Ira Newborn | Original Music Composer |
| Editing | Tony Lombardo | Editor |
| Production | Risa Bramon Garcia | Casting |
| Production | Tom Jacobson | Producer |
| Directing | John Hughes | Director |
| Production | John Hughes | Producer |
| Editing | Peck Prior | Editor |
| Editing | Lou Lombardo | Editor |
| Production | Billy Hopkins | Casting |
| Writing | John Hughes | Writer |
| Camera | John Waldo | Second Assistant Camera |
| Production | Tom Udell | Unit Production Manager |
| Art | Amie McCarthy Winn | Props |
| Production | Raymond Hartwick | Unit Production Manager |
| Directing | Marshall Schlom | Script Supervisor |
| Camera | Michael Stone | Camera Operator |
| Directing | Anne Rapp | Script Supervisor |
| Art | Thomas M. Jones | Set Dresser |
| Camera | Michelle Crenshaw | Second Assistant Camera |
| Sound | Greg Agalsoff | Boom Operator |
| Art | Daniel Loren May | Set Decoration |
| Lighting | Mel P. Mack | Electrician |
| Production | Alan C. Blomquist | Unit Production Manager |
| Camera | Alex Touyarot | First Assistant Camera |
| Sound | James R. Alexander | Sound Mixer |
| Production | Ramey E. Ward | Associate Producer |
| Camera | Danial Miller | Dolly Grip |
| Art | Jerry Moss | Property Master |
| Art | Louis M. Mann | Assistant Art Director |
| Art | Kim S. Hobbs | Lead Set Dresser |
| Art | Casey Hallenbeck | Leadman |
| Art | John W. Corso | Production Design |
| Directing | Thomas J. Mack | First Assistant Director |
| Sound | Ron Payne | Music Coordinator |
| Art | Daniel B. Clancy | Set Dresser |
| Costume & Make-Up | Daniel J. Lester | Costume Supervisor |
| Production | Mary Nitti | Assistant Production Coordinator |
| Lighting | Robert Swander | Chief Lighting Technician |
| Lighting | Ronald W. McLeish | Chief Lighting Technician |
| Camera | Mark E. Matthys | Grip |
| Sound | Lou Kleinman | Sound Editor |
| Production | Shari Leibowitz | Production Coordinator |
| Production | Adena Lazan | Accounting Clerk Assistant |
| Editing | Ed O'Malley | Assistant Editor |
| Camera | Morgan Michael Lewis | Key Grip |
| Camera | James O. Oakes | Best Boy Grip |
| Costume & Make-Up | Jamie Sue Weiss | Makeup Artist |
| Costume & Make-Up | Linda Rizzuto | Additional Hairstylist |
| Editing | Gina Lombardo | First Assistant Editor |
| Production | William H. Brown | Associate Producer |
| Directing | Forrest L. Futrell | Second Second Assistant Director |
| Crew | Jeff Jarvis | Special Effects Coordinator |
| Costume & Make-Up | Jacqueline G. Arthur | Costume Assistant |
| Costume & Make-Up | Ben Nye Jr. | Makeup Designer |
| Art | Steven Curtis Husch | Props |
| Production | Tammy Karabas | Production Secretary |
| Crew | Danny Cangemi | Special Effects |
| Editing | Tony Taurus | Assistant Editor |
| Costume & Make-Up | Ilene Giardini | Costumer |
| Costume & Make-Up | Silvio Scarano | Costumer |
| Lighting | John Swanders | Assistant Chief Lighting Technician |
| Camera | Dan McKenzie | Grip |
| Sound | Stan Gilbert | ADR Supervisor |
| Lighting | Roy A. McLeish | Electrician |
| Crew | Charles J. Brady Jr. | Craft Service |
| Editing | John Lafferty | Assistant Editor |
| Sound | George Fredrick | Sound Editor |
| Sound | Cindy Marty | Sound Editor |
| Editing | Donah Bassett | Negative Cutter |
| Sound | Per Hallberg | Assistant Sound Editor |
| Art | Jacob Zawacki | Construction Foreman |
| Camera | Dean Williams | Still Photographer |
| Art | Kenneth J. Gagnon Sr. | Construction Coordinator |
| Crew | John Hardy | Transportation Co-Captain |
| Sound | Doug Hemphill | Sound Re-Recording Mixer |
| Production | Suzanne Smith | Casting Associate |
| Sound | Frank Smathers | Sound Editor |
| Sound | Gary Alexander | Sound Re-Recording Mixer |
| Crew | Patrick J. Lynn | Transportation Co-Captain |
| Camera | Gregory Lundsgaard | Second Unit Director of Photography |
| Sound | Scott Martin Gershin | Sound Editor |
| Sound | Jeff Rosen | Sound Editor |
| Sound | Tom Kramer | Music Editor |
| Crew | Armand Paoletti | Transportation Coordinator |
| Crew | Holly Hudecek | Studio Teacher |
| Production | Paul Adler | Casting Associate |
| Costume & Make-Up | Dione Taylor | Hairstylist |
| Sound | Michael Magill | Sound Editor |
| Sound | Jeff Carson | Music Editor |
| Crew | James Hogan | Transportation Captain |
| Crew | Michael D. Cronin | Set Medic |
| Editing | Jerrie Fowler | Assistant Editor |
| Sound | Larry Kemp | Sound Editor |
| Crew | William Shane Grisco | Animal Coordinator |
| Editing | Tim Silano | First Assistant Editor |
| Sound | Tom Bellfort | Supervising Sound Editor |
| Crew | Joan Eisenberg | Unit Publicist |
| Art | Steve Homa | Greensman |
| Directing | William H. Brown | Second Unit Director |
| Production | Jacolyn Baker | Location Manager |
| Sound | Wylie Stateman | Supervising Sound Editor |
| Sound | Bob Beher | Assistant Sound Editor |
| Sound | Chris Jenkins | Sound Re-Recording Mixer |
| Art | Jeff Passanante | Construction Coordinator |
| Art | James M. Davis | Construction Foreman |
| Crew | Ken Blazer | Stunt Double |
| Camera | Chris Hayes | Camera Operator |
| Crew | Miranda Garrison | Choreographer |
| Crew | Bob Elmore | Stunt Double |
| Crew | M. James Arnett | Stunt Coordinator |
| Directing | David Kelley | Second Assistant Director |
| Crew | Manny Perry | Stunt Double |
| Costume & Make-Up | Marilyn Vance | Costume Design |
