Marie is een vampier met een geweten, die op zoek is naar seks en bloed. Zij besluit haar werkterrein te verleggen naar Pittsburgh, waar de maffia heerst. Als ze een hapje neemt van Sal Macelli, een hoge gangsterbaas, beginnen de problemen. Als zij er niet in slaagt om haar slachtoffers uit te schakelen, worden ze zelf vampieren, en omdat de maffiabaas het overleeft dreigen er grote problemen. Ondertussen wordt ze verliefd op de politieagent die achter de maffiabaas aanzit...
Nee, helaas is Innocent Blood nog niet beschikbaar op Netflix in Nederland.
| Directing | John Landis | Director |
| Writing | Michael Wolk | Screenplay |
| Editing | Dale Beldin | Editor |
| Production | Leslie Belzberg | Producer |
| Camera | Mac Ahlberg | Director of Photography |
| Sound | Ira Newborn | Original Music Composer |
| Production | Lee Rich | Producer |
| Crew | Glory Fioramonti | Stunts |
| Crew | Tom Elliott | Stunts |
| Costume & Make-Up | Deborah Nadoolman Landis | Costume Design |
| Production | Michael Wolk | Associate Producer |
| Directing | Susan Pickett | Second Second Assistant Director |
| Art | Martin Charles | Art Direction |
| Production | Janet L. Wattles | Production Supervisor |
| Production | Paul Deason | Unit Production Manager |
| Art | Karl J. Martin | Set Designer |
| Art | Jim Schneider | Lead Set Dresser |
| Art | Peg Cummings | Set Decoration |
| Directing | Rosemary C. Cremona | Second Assistant Director |
| Art | Richard Sawyer | Production Design |
| Directing | Nicholas Mastandrea | First Assistant Director |
| Production | Jonathan Sheinberg | Executive Producer |
| Costume & Make-Up | Ron Berkeley | Makeup Artist |
| Crew | Marian Green | Stunts |
| Crew | Bill Corso | Makeup Effects |
| Crew | Jeannie Epper | Stunts |
| Crew | Bob Minor | Stunts |
| Crew | Kurt Bryant | Stunts |
| Crew | Joni Avery | Stunt Double |
| Crew | Spiro Razatos | Stunts |
| Crew | Troy Brown | Stunts |
| Crew | Merritt Yohnka | Stunts |
| Crew | Andy Gill | Stunts |
| Crew | Charles Croughwell | Stunts |
| Crew | Syd Dutton | Special Effects |
| Crew | Jeff Cadiente | Stunts |
| Crew | Monty Cox | Stunts |
| Crew | Clay Boss | Stunts |
| Crew | Mike De Luna | Stunts |
| Crew | Richard Epper | Stunts |
| Crew | Steve Hulin | Stunts |
| Crew | Andree Gibbs | Stunts |
| Crew | Keii Johnston | Stunts |
| Crew | Bill McIntosh | Stunts |
| Crew | Brad Orrison | Stunts |
| Crew | Buck McDancer | Stunts |
| Crew | Don Pulford | Stunts |
| Crew | Mark Orrison | Stunts |
| Crew | Branscombe Richmond | Stunts |
| Crew | Michael J. Sarna | Stunts |
| Art | Penelope Gottlieb | Title Designer |
