Felix Ungar en Oscar Madison woonden ooit samen, maar ze hebben elkaar nu al 17 jaar niet meer gezien. Maar omdat de zoon van Oscar, Brucey gaat trouwen met de dochter van Felix, Hannah ontmoeten ze elkaar weer. Ze huren een auto om gezamenlijk naar San Malina te rijden. Ze verdwalen echter en zitten, net als vroeger, weer met elkaar opgescheept.
Nee, helaas is The Odd Couple II nog niet beschikbaar op Netflix in Nederland.
| Writing | Neil Simon | Screenplay |
| Directing | Howard Deutch | Director |
| Crew | Kenny Endoso | Stunts |
| Crew | Danny Wynands | Stunts |
| Sound | Alan Silvestri | Original Music Composer |
| Production | Elena Spiotta | Associate Producer |
| Crew | Robbie Knott | Special Effects Coordinator |
| Art | Dan Bishop | Production Design |
| Production | Robert W. Cort | Producer |
| Art | Kristen Toscano Messina | Set Decoration |
| Production | Jane Shannon-Smith | Casting Director |
| Production | David Madden | Producer |
| Costume & Make-Up | Janis Clark | Hair Supervisor |
| Costume & Make-Up | Steve Artmont | Makeup Supervisor |
| Camera | Jamie Anderson | Director of Photography |
| Art | Jeff Knipp | Art Direction |
| Sound | Sandy Berman | Supervising Sound Editor |
| Production | Alex Wald | Casting Director |
| Sound | Murray Deutch | Music Supervisor |
| Sound | Andrew Silver | Music Editor |
| Sound | Stu Cantor | Music Supervisor |
| Sound | Kenneth Karman | Music Editor |
| Sound | Monica Corton | Music Supervisor |
| Crew | Tommy J. Huff | Stunts |
| Art | Jeff Brown | Greensman |
| Lighting | David Morton | Lighting Technician |
| Crew | Manny Perry | Stunts |
| Crew | William Barillaro | Stunts |
| Crew | Randy Peterson | Transportation Captain |
| Costume & Make-Up | Lisa Jensen | Costume Design |
| Crew | Steve M. Davison | Stunts |
| Camera | Clyde E. Bryan | First Assistant Camera |
| Editing | Seth Flaum | Editor |
| Crew | Jack Carpenter | Driver |
| Sound | Nicholas R. Allen | Boom Operator |
| Crew | Charlie Brewer | Stunt Coordinator |
| Crew | John C. Meier | Stunts |
| Production | Neil Simon | Producer |
| Crew | Michelle Johnston | Choreographer |
| Sound | James Thatcher | Musician |
| Sound | Tom Boyd | Musician |
| Crew | Robert 'Bobby Z' Zajonc | Aerial Coordinator |
| Editing | Mark Bourgeois | Assistant Editor |
| Editing | Theresa Repola Mohammed | Negative Cutter |
