Een pratende parasiet - die de vorm van een worm heeft - spuit psychedelische vloeistoffen in de hersenen van Brian. Het gevolg daarvan is dat Brian begint te hallucineren en verslaafd raakt aan de vloeistoffen. De parasiet doet dat echter niet voor niks. Hij eist dat Brian hem menselijke hersenen voedt...
Nee, helaas is Brain Damage nog niet beschikbaar op Netflix in Nederland.
| Directing | Greg Lamberson | First Assistant Director |
| Directing | Frank Henenlotter | Director |
| Writing | Frank Henenlotter | Writer |
| Production | Edgar Ievins | Producer |
| Production | Andre Blay | Executive Producer |
| Production | Al Eicher | Executive Producer |
| Sound | Peter Clark | Sound Editor |
| Sound | Russell Jessum | Sound Recordist |
| Sound | Aaron Nathanson | Sound Mixer |
| Sound | Bruce Torbet | Sound Editor |
| Sound | Joe Warda | Sound |
| Costume & Make-Up | Ivy Rosovsky | Wardrobe Designer |
| Crew | Matthias Donnelly | Additional Music |
| Costume & Make-Up | Gabriel Bartalos | Special Effects Makeup Artist |
| Camera | Bruce Torbet | Director of Photography |
| Costume & Make-Up | James McLoughlin | Special Effects Makeup Artist |
| Costume & Make-Up | Nick Santeramo | Special Effects Makeup Artist |
| Costume & Make-Up | Richard Mayone | Special Effects Makeup Artist |
| Writing | David Kindlon | Characters |
| Production | Charles C. Bennett | Associate Producer |
| Production | Ray Sundlin | Associate Producer |
| Sound | Clutch Reiser | Music |
| Sound | Gus Russo | Music |
| Editing | Frank Henenlotter | Editor |
| Editing | James Y. Kwei | Editor |
| Art | Ivy Rosovsky | Art Direction |
| Costume & Make-Up | Dan Frye | Makeup Artist |
| Production | Ed Walloga | Production Manager |
| Visual Effects | Al Magliochetti | Visual Effects Supervisor |
| Camera | Richard Boyle | Grip |
| Camera | Peter Clark | Camera Operator |
| Camera | J. Michael Muro | Steadicam Operator |
| Editing | Briton J. Petrucelly | Assistant Editor |
| Writing | Gabriel Bartalos | Characters |
