De film is gebaseerd op het verhaal van Barry Seal. Seal smokkelde als piloot drugs voor de Colombiaanse drugsbaron Pablo Escobar. Na zijn aanhouding werd hij door de CIA gerekruteerd voor een undercoveroperatie.
| Directing | Doug Liman | Director |
| Writing | Gary Spinelli | Writer |
| Camera | César Charlone | Director of Photography |
| Crew | Amy Lynn Tuttle | Utility Stunts |
| Crew | Joey Box | Stunt Coordinator |
| Production | Ray Angelic | Producer |
| Production | Doug Davison | Producer |
| Production | Brian Grazer | Producer |
| Production | Brian Oliver | Producer |
| Production | Kim Roth | Producer |
| Production | Tyler Thompson | Producer |
| Production | Mindy Marin | Casting |
| Art | Dan Weil | Production Design |
| Art | Patricia Arango | Art Direction |
| Art | Christina Eunji Kim | Art Direction |
| Art | Justin O'Neal Miller | Art Direction |
| Art | María Fernanda Muñoz | Art Direction |
| Art | Rachel Nowik | Art Department Coordinator |
| Art | Alanna Smith | Art Department Coordinator |
| Art | Douglas Womack | Construction Coordinator |
| Art | Kris Peck | Property Master |
| Art | Elizabeth Cummings | Supervising Art Director |
| Art | Kelley Burney | Set Decoration |
| Costume & Make-Up | Kym Barrett | Costume Design |
| Costume & Make-Up | Jenny Gering | Costume Design |
| Crew | Hayden Bilson | Armorer |
| Directing | Jody Blose | Script Supervisor |
| Crew | Frédéric North | Aerial Coordinator |
| Crew | Jim Garland | Pilot |
| Crew | Alan D. Purwin | Pilot |
| Production | Ianthe Jeanne Dugan | Researcher |
| Sound | Todd Kasow | Music Editor |
| Sound | Tom Kramer | Music Editor |
| Sound | Annette Kudrak | Music Editor |
| Sound | Gabe Hilfer | Music Supervisor |
| Sound | Julianne Jordan | Music Supervisor |
| Costume & Make-Up | Mercedes Cook | Assistant Costume Designer |
| Costume & Make-Up | Thom Heyer | Assistant Costume Designer |
| Costume & Make-Up | Bridget Shields | Assistant Costume Designer |
| Costume & Make-Up | Abby Walton | Assistant Costume Designer |
| Costume & Make-Up | Chelsea Staebell | Assistant Costume Designer |
| Costume & Make-Up | Camila Olarte | Assistant Costume Designer |
| Costume & Make-Up | Aimee Campolucci | Ager/Dyer |
| Costume & Make-Up | Pam Aaron | Key Costumer |
| Costume & Make-Up | Wendy Talley | Key Costumer |
| Costume & Make-Up | Fran Beaudry | Seamstress |
| Costume & Make-Up | Libby Culligan | Set Costumer |
| Costume & Make-Up | Julian Grijalba | Set Costumer |
| Costume & Make-Up | Alexyz Danine Kemp | Set Costumer |
| Costume & Make-Up | Olivia Vestina Torres | Set Costumer |
| Costume & Make-Up | Natasha Romanow | Set Costumer |
| Costume & Make-Up | Tom Schmitz | Tailor |
| Camera | Dylan Goss | Aerial Director of Photography |
| Camera | Christine Oeurn | Camera Technician |
| Camera | Christopher TJ McGuire | Steadicam Operator |
| Lighting | Kelly Clear | Gaffer |
| Lighting | Kevin Gazdik | Gaffer |
| Camera | C. Ashley Sudge | Dolly Grip |
| Camera | Michael Duarte | Key Grip |
| Camera | James Selph | Key Grip |
| Lighting | Jerry Chief Parker | Rigging Gaffer |
| Lighting | Tyler Childs | Rigging Gaffer |
| Lighting | Tony Murima | Rigging Grip |
| Lighting | Tommy Donald | Rigging Grip |
| Camera | David James | Still Photographer |
| Crew | Adam Meadows | Video Assist Operator |
| Camera | Edward Button | Additional Photography |
| Camera | Eliza Morse | Additional Still Photographer |
| Lighting | Cristen Clark | Lighting Technician |
| Lighting | Killian Clear | Lighting Technician |
| Costume & Make-Up | Marie Larkin | Hair Department Head |
| Costume & Make-Up | Jay Ferrara | Hairstylist |
| Costume & Make-Up | Alice Moore | Hairstylist |
| Costume & Make-Up | Teresa Morgan | Hairstylist |
| Costume & Make-Up | Sarah Monzani | Makeup Department Head |
| Costume & Make-Up | Olga Turrini Bernardoni | Makeup Department Head |
| Costume & Make-Up | Anthony Brooks | Makeup Artist |
| Costume & Make-Up | Jamie Cline | Makeup Artist |
| Costume & Make-Up | Laura Dandridge | Makeup Artist |
| Costume & Make-Up | Leigh Ann Yandle | Key Makeup Artist |
| Visual Effects | Kevin Scott | Animation Director |
| Visual Effects | Bryan T. Evans | Matchmove Supervisor |
| Visual Effects | Grant Lynch | VFX Editor |
| Visual Effects | Greg Takacs | VFX Editor |
| Visual Effects | Chris Hamilton | VFX Editor |
| Visual Effects | Jae Won D. Lee | Visual Effects Coordinator |
| Visual Effects | Jennifer Ramos | Visual Effects Coordinator |
| Visual Effects | Justin Rogers-CdeBaca | Visual Effects Coordinator |
| Visual Effects | Michael Tanton | Visual Effects Coordinator |
| Visual Effects | Sara Woomer | Visual Effects Coordinator |
| Crew | Matt Mayer | Visual Effects Editor |
| Crew | Jaime Fok | Visual Effects Editor |
| Visual Effects | Gayle Busby | Visual Effects Producer |
| Visual Effects | Sarah McMurdo | Visual Effects Producer |
| Visual Effects | Eric J. Robertson | Visual Effects Producer |
| Visual Effects | Justin Ball | Visual Effects Supervisor |
| Visual Effects | Craig Calvert | Visual Effects Supervisor |
| Visual Effects | Scott Riopelle | Visual Effects Supervisor |
| Visual Effects | David Fletcher | Special Effects Supervisor |
| Crew | Thomas Kittle | Special Effects Coordinator |
| Crew | David K. Nami | Special Effects Coordinator |
| Sound | Anthony Ortiz | Boom Operator |
| Sound | Branka Mrkic | Dialogue Editor |
| Sound | Marko Costanzo | Foley |
| Sound | Steven Visscher | Foley |
| Sound | Dave Flynch | Foley Editor |
| Sound | Paul Hsu | Sound Designer |
| Sound | Allan Zaleski | Sound Effects Editor |
| Sound | Bob Chefalas | Sound Re-Recording Mixer |
| Sound | Tom Fleischman | Sound Re-Recording Mixer |
| Sound | Seva Solntsev | Sound Re-Recording Mixer |
| Sound | Ron Bochar | Supervising Sound Editor |
| Sound | Philip Stockton | Supervising Sound Editor |
| Editing | Tif Luckenbill | Digital Intermediate |
| Editing | Pete Polyakov | Digital Intermediate |
| Editing | James W. Harrison III | First Assistant Editor |
| Editing | Arturo Sosa | Assistant Editor |
| Editing | Robert Grigsby Wilson | Assistant Editor |
| Costume & Make-Up | Elizabeth Robinson | Key Hair Stylist |
| Production | Tyler Hohmann | Location Assistant |
| Sound | Christophe Beck | Original Music Composer |
| Production | Alison Winter | Associate Producer |
| Production | Brandt Andersen | Executive Producer |
| Production | Michael Bassick | Executive Producer |
| Production | Ray Chen | Executive Producer |
| Production | Terry Dougas | Executive Producer |
| Production | Michael Finley | Executive Producer |
| Production | Eric Greenfeld | Executive Producer |
| Production | Paris Kassidokostas-Latsis | Executive Producer |
| Production | Johnny Lin | Executive Producer |
| Production | Philip Moross | Executive Producer |
| Production | Michael Plank | Executive Producer |
| Production | Joshua Skurla | Executive Producer |
| Production | Gary Spinelli | Executive Producer |
| Production | Marcos Tellechea | Executive Producer |
| Production | Jill Ahrens | Co-Executive Producer |
| Production | Ryan Ahrens | Co-Executive Producer |
| Production | Andrés Calderón | Co-Executive Producer |
| Production | Jean-Luc De Fanti | Co-Executive Producer |
| Production | Daniel Lanmi | Co-Executive Producer |
| Production | Beely Lee | Co-Executive Producer |
| Production | Allen Liu | Co-Executive Producer |
| Production | James H. Pang | Co-Executive Producer |
| Production | Lauren Selig | Co-Executive Producer |
| Production | Christopher Woodrow | Co-Executive Producer |
| Production | Leo Shi Young | Co-Executive Producer |
| Production | Rita Harrell | Local Casting |
| Production | Jen Kelley | Local Casting |
| Sound | Michael Paraskevas | Music |
| Editing | Andrew Mondshein | Editor |
| Editing | Saar Klein | Additional Editor |
| Editing | Dylan Tichenor | Additional Editor |
| Crew | Mario Pérez | Stunt Driver |
| Crew | Robert Alonzo | Stunt Coordinator |
| Crew | Max Calder | Stunt Double |
| Crew | Niko Dalman | Stunt Double |
| Crew | Elena Sanchez | Stunt Double |
| Crew | Christopher C. Padilla | Stunts |
| Crew | Tyler Vogt | Stunts |
| Crew | Ben Prine | Set Medic |
| Crew | Claire Raskind | Unit Publicist |
