Ash en zijn vrienden zijn uitgenodigd op een groot festival, waar gevierd wordt dat lang geleden held Sir Aaron en zijn Pokémon Lucario de wereld hebben gered van de ondergang door gebruik te maken van de krachten van een Magische Boom. Ash en Pikachu winnen de Pokémon wedstrijd, krijgen de titel 'Beschermer van Aura' en mogen de staf van Sir Aaron voor een avond vasthouden. De staf waarvan men denkt dat de verdwenen Pokémon Lucario er al jaren in gevangen zit. Maar de feestvreugde is snel voorbij als de mysterieuze Pokemon Mew opduikt en Pikachu meeneemt. Op datzelfde moment weet Lucario uit de staf van Sir Aaron te ontsnappen. Met hulp van Lucario gaat Ash op zoek naar de Magische Boom en de legendarische Pokémon Mew. De toekomst van de wereld hangt nu af van de hechte vriendschap tussen mensen en Pokémons.
Nee, helaas is Pokémon: Lucario en het Mysterie van Mew nog niet beschikbaar op Netflix in Nederland.
| Directing | 湯山邦彦 | Director |
| Visual Effects | 佐藤美由紀 | Color Designer |
| Art | 湯山邦彦 | Storyboard Artist |
| Art | 増井壮一 | Storyboard Artist |
| Art | 浅田裕二 | Storyboard Artist |
| Art | 宮尾佳和 | Storyboard Artist |
| Art | Tetsu Kimura | Storyboard Artist |
| Visual Effects | Takuya Matsumoto | Animation Director |
| Sound | 吉村由美 | Songs |
| Sound | 大貫亜美 | Songs |
| Visual Effects | Shiro Kudaka | Key Animation |
| Visual Effects | Tsuneo Ninomiya | Key Animation |
| Visual Effects | 吉田大輔 | Key Animation |
| Visual Effects | 佐藤陵 | Key Animation |
| Visual Effects | Masami Takebuchi | Key Animation |
| Visual Effects | Junko Isaka | Key Animation |
| Visual Effects | Akiko Nakamura | Key Animation |
| Visual Effects | Tadaaki Miyata | Key Animation |
| Visual Effects | 渡辺敦子 | Key Animation |
| Visual Effects | Midori Nagaoka | Key Animation |
| Visual Effects | 小林ゆかり | Key Animation |
| Visual Effects | 高橋英樹 | Key Animation |
| Visual Effects | Tomoko Takei | Key Animation |
| Crew | Junichi Masuda | Creator |
| Production | Tsunekazu Ishihara | Production Supervisor |
| Visual Effects | Yōichi Kotabe | Animation Supervisor |
| Production | Hiroaki Tsuru | Executive Producer |
| Production | Shukichi Kanda | Producer |
| Production | Yukako Matsusako | Producer |
| Directing | 浅田裕二 | Assistant Director |
| Production | 岡本順哉 | Producer |
| Writing | 園田英樹 | Screenplay |
| Production | 久保雅一 | Executive Producer |
| Production | Choji Yoshikawa | Producer |
| Production | Toshiaki Okuno | Producer |
| Crew | Ken Sugimori | Creator |
| Crew | 田尻智 | Creator |
| Production | Takemoto Mori | Producer |
| Editing | Mizue Ueda | Colorist |
| Directing | 吉川博明 | Assistant Director |
| Directing | 渡辺正彦 | Assistant Director |
| Sound | 三間雅文 | Sound Director |
| Visual Effects | 一石小百合 | Character Designer |
| Visual Effects | 高橋美香 | Animation Director |
| Camera | Takuya Mizutani | Director of Photography |
| Directing | Naohito Takahashi | Assistant Director |
| Visual Effects | Akihiro Tamagawa | Animation Director |
| Editing | Toshio Henmi | Editor |
| Visual Effects | Senri Ikehara | Animation Director |
| Visual Effects | Tokuhiro Matsubara | Character Designer |
| Visual Effects | 毛利和昭 | Animation Director |
| Visual Effects | Katsunori Kimizuka | Animation Director |
| Visual Effects | 毛利和昭 | Character Designer |
| Visual Effects | Takayuki Shimura | Animation Director |
| Visual Effects | Yuko Inoue | Animation Director |
| Editing | 上村貴子 | Colorist |
| Directing | 鎌倉由実 | Assistant Director |
| Directing | Masakatsu Iijima | Assistant Director |
| Visual Effects | Kunihiko Natsume | Animation Director |
| Sound | Kazuo Shinohara | Music Producer |
| Sound | Yuji Saito | Music Producer |
| Visual Effects | 相澤昌弘 | Animation Director |
| Art | Masatoshi Muto | Art Direction |
| Sound | Shinji Miyazaki | Music |
| Writing | 田尻智 | Original Story |
