De film speelt zich af op de jungle-achtige thuisplaneet van de Predators. Op deze planeet huist ook een 'Mega-Predator' die elk jaar een groep van de gevaarlijkste individuen van de planeet aarde ontvoert, om ze vervolgens als prooi vrij te laten in de dodelijke jungle van de Predator-thuisplaneet. Royce (Adrien Brody) is de leider van een groepje huurlingen, dat onder andere bestaat uit een taaie vrouwelijke moordenaar, een man die totaal niet bang is om te sterven en een voormalige Russisch geheimagent. Samen moeten ze zien te overleven in de wildernis terwijl ze wanhopig proberen uit te vinden wat er met hen is gebeurd en door wie of wat ze worden opgejaagd...
Nee, helaas is Predators nog niet beschikbaar op Netflix in Nederland.
| Editing | Dan Zimmerman | Editor |
| Production | John Davis | Producer |
| Production | Alex Young | Executive Producer |
| Production | J.C. Cantu | Casting |
| Sound | John Debney | Original Music Composer |
| Camera | Pados Gyula | Director of Photography |
| Production | Robert Rodriguez | Producer |
| Costume & Make-Up | Nina Proctor | Costume Design |
| Writing | Alex Litvak | Writer |
| Production | Jaina Ashton | Casting |
| Production | Mary Vernieu | Casting |
| Production | Elizabeth Avellan | Producer |
| Directing | Nimród Antal | Director |
| Writing | Michael Finch | Writer |
| Crew | Heidi Pascoe | Stunt Double |
| Crew | Tim Trella | Stunts |
| Directing | Gina Grande | Script Supervisor |
| Art | Jeff B. Adams Jr. | Set Designer |
| Crew | Joe Montenegro | Special Effects Coordinator |
| Sound | Angelo Palazzo | Sound Effects Editor |
| Costume & Make-Up | Cindy Renaud-Kim | Tailor |
| Writing | Jim Thomas | Characters |
| Art | Richard J. Bell | Greensman |
| Art | Joe McCusker | Construction Coordinator |
| Sound | Joaquin Gonzalo Avellán | Foley Editor |
| Crew | Jeffrey J. Dashnaw | Stunt Coordinator |
| Lighting | Spencer Pharr | Lighting Technician |
| Camera | Henry Tirl | Steadicam Operator |
| Art | Kurt Volk | Title Designer |
| Art | David Hack | Set Decoration |
| Sound | William Jacobs | Sound Editor |
| Crew | Travis Smith | Visual Effects Editor |
| Camera | Mark Gerasimenko | Camera Operator |
| Art | Pedro Barquin | Greensman |
| Sound | Tim Rakoczy | Supervising Sound Editor |
| Camera | Rico Torres | Still Photographer |
| Crew | Larry Zanoff | Armorer |
| Camera | Ferrell A. Shinnick | Key Grip |
| Art | Steve Joyner | Production Design |
| Sound | David Bach | ADR Editor |
| Lighting | jonathan Swartz | Lighting Director |
| Crew | Steve M. Davison | Stunt Coordinator |
| Sound | Clayton Weber | Foley Editor |
| Visual Effects | Richard Wood | Special Effects Supervisor |
| Sound | Brad Dechter | Orchestrator |
| Costume & Make-Up | Ermahn Ospina | Makeup Department Head |
| Art | Ana Martínez | Art Department Coordinator |
| Sound | Brad Engleking | Dialogue Editor |
| Lighting | Sean Noel Walker | Lighting Director |
| Art | Adele Plauche | Set Designer |
| Costume & Make-Up | Amy Maner | Costume Supervisor |
| Directing | Brian Bettwy | First Assistant Director |
| Visual Effects | Jabbar Raisani | Visual Effects Supervisor |
| Lighting | Colin J. Campbell | Gaffer |
| Sound | Paula Fairfield | Sound Designer |
| Sound | Tom Sturgis | Boom Operator |
| Camera | Neil Fraser | Dolly Grip |
| Art | Tommy Tomlinson | Property Master |
| Art | Caylah Eddleblute | Production Design |
| Art | Mark Hanks | Leadman |
| Sound | Carla Murray | Sound Designer |
| Costume & Make-Up | Joe Rivera | Hair Department Head |
| Production | Logan Cooper | Location Manager |
| Sound | Jeff Carson | Music Editor |
| Production | Cynthia Streit | Production Coordinator |
| Crew | Hank Amos | Stunts |
| Crew | Norman Mora | Stunts |
| Crew | Michael Hansen | Stunts |
| Crew | Jeremy Fitzgerald | Stunts |
| Crew | Jon Sakata | Stunts |
| Crew | Steve Boyles | Stunts |
| Crew | Dick Hancock | Stunts |
| Crew | James C. Lewis | Stunts |
| Crew | Ryan Happy | Stunts |
| Crew | James Ryan | Stunts |
| Crew | Joey Anaya | Stunts |
| Crew | Brian L. Keaulana | Stunts |
| Crew | Dana Reed | Stunts |
| Crew | David Schultz | Stunts |
| Crew | Aaron Walters | Stunts |
| Crew | Brian Munce | Stunts |
| Crew | Ryan Ryusaki | Stunts |
| Art | Francois Larosa | Greensman |
| Crew | Troy Robinson | Stunts |
| Crew | Bob Brown | Stunts |
| Directing | David Rimer | Second Assistant Director |
| Production | Bill Scott | Co-Producer |
| Crew | Tom Proper | Post Production Supervisor |
| Production | Ron Schmidt | Unit Production Manager |
| Directing | Susan Jasso | Second Second Assistant Director |
| Production | Tom Proper | Associate Producer |
| Writing | John Thomas | Characters |
| Visual Effects | Jan Philip Cramer | Animation Supervisor |
