Er heeft zich een vreemde mutatie voorgedaan in de vampierenwereld, genaamd The Reaper. De bloeddorst van deze vampieren is zo groot dat ze het op zowel mensen als andere vampiers voorzien hebben. Blade en Whistler besluiten samen te werken met The Bloodpackt, een elite team vampiers, aangezien ze dit maal een gezamenlijk doel hebben.
Nee, helaas is Blade II nog niet beschikbaar op Netflix in Nederland.
| Production | Lynn Harris | Executive Producer |
| Sound | Marco Beltrami | Original Music Composer |
| Writing | David S. Goyer | Writer |
| Production | Wesley Snipes | Producer |
| Production | Peter Frankfurt | Producer |
| Writing | Marv Wolfman | Characters |
| Directing | Guillermo del Toro | Director |
| Production | Patrick J. Palmer | Producer |
| Production | Toby Emmerich | Executive Producer |
| Production | David S. Goyer | Executive Producer |
| Production | Nancy Foy | Casting |
| Camera | Gabriel Beristain | Director of Photography |
| Writing | Gene Colan | Characters |
| Production | Avi Arad | Executive Producer |
| Editing | Peter Amundson | Editor |
| Production | Stan Lee | Executive Producer |
| Costume & Make-Up | Wendy Partridge | Costume Design |
| Production | Michael De Luca | Executive Producer |
| Costume & Make-Up | Gary Archer | Prosthetics |
| Crew | Clay Cullen | Stunts |
| Art | Mike Hyrman | Art Department Coordinator |
| Art | Michael Madden | Set Designer |
| Art | Carol Spier | Production Design |
| Art | Martin Vačkář | Assistant Art Director |
| Art | Dan Morski | Co-Art Director |
| Production | Pavel Typolt | Production Manager |
| Production | Wendy Cox | Production Supervisor |
| Costume & Make-Up | Jeanette Freeman | Hairstylist |
| Art | Bruce DiValerio | Construction Coordinator |
| Art | Gordon White | Set Designer |
| Art | Milena Koubková | Set Designer |
| Production | Michelle Weller | Production Supervisor |
| Art | Jeffrey Kushon | Set Decoration |
| Art | Phillip Tellez | Construction Coordinator |
| Art | Jaromír Švarc | Art Direction |
| Art | James F. Truesdale | Art Direction |
| Sound | Scott Martin Gershin | Sound Designer |
| Sound | Mathew Waters | Supervising Sound Editor |
| Art | Constantine Sekeris | Conceptual Design |
| Sound | John Ross | Sound Re-Recording Mixer |
| Sound | Michael Keller | Sound Re-Recording Mixer |
| Art | Peter Nicolakakos | Set Decoration |
| Costume & Make-Up | Nikita Rae | Makeup Artist |
| Costume & Make-Up | Michelle Taylor | Makeup Artist |
| Sound | Scott Martin Gershin | Supervising Sound Editor |
| Crew | Peter S. Elliot | Visual Effects Editor |
| Camera | Guy Hodgen | Additional Camera |
| Visual Effects | Susan MacLeod | Visual Effects Producer |
| Lighting | Jaromir Simek | Gaffer |
| Crew | Barbora Kolarova | Special Effects Coordinator |
| Visual Effects | Blair Clark | Visual Effects Supervisor |
| Crew | Sarah Schubart | Visual Effects Editor |
| Camera | Anthony Gaudioz | Camera Operator |
| Visual Effects | David Sosalla | Visual Effects Supervisor |
| Crew | Viktor Lonek | Video Assist Operator |
| Visual Effects | Craig Hayes | Visual Effects Supervisor |
| Visual Effects | George Macri | Visual Effects Producer |
| Camera | Craig Fikse | Steadicam Operator |
| Crew | Aaron Skalka | Transportation Coordinator |
| Visual Effects | Terry Bradley | Visual Effects Supervisor |
| Visual Effects | Dominic Parker | Visual Effects Supervisor |
| Crew | Dirk Westervelt | Visual Effects Editor |
| Lighting | H. Mark Vuille | Gaffer |
| Visual Effects | Robert Duncan | Visual Effects Supervisor |
| Visual Effects | Justin Martin | Visual Effects Supervisor |
| Visual Effects | Nordin Rahhali | Visual Effects Supervisor |
| Visual Effects | Edward Irastorza | Visual Effects Producer |
| Visual Effects | Bob Munroe | Visual Effects Supervisor |
| Crew | Pavel Cajzl | Stunt Coordinator |
| Camera | Klaus Fuxjäger | Camera Operator |
| Visual Effects | Nicholas Brooks | Visual Effects Supervisor |
| Visual Effects | Ruth Greenberg | Visual Effects Producer |
| Visual Effects | Dominic Sidoli | Visual Effects Producer |
| Sound | Bill Abbott | Music Editor |
| Sound | Brian Richards | Music Editor |
| Crew | Vaclav Mottl | Transportation Coordinator |
| Production | Douglas Dresser | Location Manager |
| Crew | Moira Houlihan | Unit Publicist |
| Crew | Jon Sperry | Dialect Coach |
| Crew | Marianna Krenova | Stand In |
| Production | Pavel Sterba | Location Manager |
| Crew | Lane Leavitt | Stunts |
| Production | John T. Sweeney | Production Coordinator |
| Crew | Mark Fattibene | CG Supervisor |
| Crew | Ladislav Beran | Choreographer |
| Crew | Jeff Ward | Martial Arts Choreographer |
| Crew | Alex Matcham | Production Controller |
| Crew | Eva Dvorakova | Set Medic |
| Costume & Make-Up | Kelly Fraser | Assistant Costume Designer |
| Art | Jan Kodera | Leadman |
| Crew | James Weston | Armorer |
| Crew | Jayson Wall | Post Production Assistant |
| Camera | Ladislav Hrubý | First Assistant Camera |
| Crew | Danny Saber | Additional Music |
| Crew | Phred Lender | Systems Administrators & Support |
| Crew | Sara Romilly | Post Production Supervisor |
| Crew | Freddy Bouciegues | Utility Stunts |
| Art | Tim Larsen | Painter |
| Costume & Make-Up | David Dupuis | Prosthetic Supervisor |
| Crew | Keith D. Fisher | Transportation Captain |
| Costume & Make-Up | Marese Langan | Key Hair Stylist |
| Crew | Chris Sposa | Cableman |
| Crew | Chris Ferrence | Driver |
| Art | John Weldy | Sculptor |
| Sound | Nerses Gezalyan | Sound mixer |
| Production | Jiri Tichacek | Production Accountant |
| Sound | Peter Eusebe | Boom Operator |
| Directing | Claudine Strasser | Script Supervisor |
| Editing | Laura Rindner | First Assistant Editor |
| Lighting | Ben Bowling | Electrician |
| Production | Robert Bernacchi | Associate Producer |
| Production | Jon Divens | Co-Producer |
| Sound | Mark Holding | Production Sound Mixer |
| Sound | John Kurlander | Scoring Mixer |
| Production | Andrew J. Horne | Co-Producer |
| Production | Sissy Grover | Production Coordinator |
| Lighting | Mike Macias | Lighting Technician |
| Sound | Happy Walters | Music Supervisor |
| Production | Andrea Clark | Casting Associate |
| Visual Effects | Asregadoo Arundi | Digital Compositors |
| Visual Effects | Nick Allder | Special Effects Supervisor |
| Lighting | Michal Houzvicka | Rigging Grip |
| Sound | Hector C. Gika | Sound Editor |
| Visual Effects | Vicki Wong | I/O Manager |
| Visual Effects | Wayne D. Barlowe | Creature Design |
| Visual Effects | Steve Watson | 24 Frame Playback |
| Visual Effects | David Rosenthal | I/O Supervisor |
| Editing | Dan Muscarella | Color Timer |
| Lighting | Petr Svoboda | Rigging Gaffer |
| Sound | Bryan Bowen | Sound Effects Editor |
| Writing | Jason Brubaker | Storyboard |
| Visual Effects | Kandece Brown | Visual Effects Coordinator |
| Production | Robert Bernacchi | Unit Production Manager |
| Art | Elinor Rose Galbraith | Supervising Art Director |
| Camera | Bill Daimant | Dolly Grip |
| Camera | John Emory | Grip |
| Costume & Make-Up | David Dupuis | Key Makeup Artist |
| Costume & Make-Up | Heather Moore | Key Costumer |
| Sound | Susan Cahill | Assistant Sound Editor |
| Sound | Pete Anthony | Conductor |
| Sound | Tom Boyd | Musician |
| Art | Miroslav Čáslavka | Set Dresser |
| Directing | Julian Wall | First Assistant Director |
| Camera | Alexandre Szabo-Fresnais | Camera Loader |
| Camera | Malcolm Sheehan | Key Grip |
| Crew | Clayton J. Barber | Fight Choreographer |
| Sound | Michael Hertlein | ADR Editor |
| Costume & Make-Up | Nigel Booth | Prosthetic Makeup Artist |
| Editing | Gary Burritt | Negative Cutter |
| Production | Clive Miles | Assistant Production Manager |
| Crew | Libor Hatas | Pilot |
| Visual Effects | Warren J.W. Leathem | Lead Animator |
| Visual Effects | Paul Anderson | 3D Artist |
| Directing | Philip Seeger | Third Assistant Director |
| Editing | Jana Lynn Gold | Associate Editor |
| Production | Minna Pyyhkala | Casting Assistant |
| Visual Effects | Jerry Corda-Stanley | CG Animator |
| Sound | Thomas Jones | ADR Supervisor |
| Sound | Craig Jurkiewicz | Foley Editor |
| Production | Stephani Hunter | Assistant Production Coordinator |
| Crew | Jonathan Eusebio | Stunts |
| Art | Greg Runnels | Swing |
| Sound | Robert Getty | Dialogue Editor |
| Sound | Louis Creveling | Dialogue Editor |
| Sound | Jed M. Dodge | Dialogue Editor |
| Art | Michael Lindsay | Property Master |
| Sound | Michael Hertlein | Dialogue Editor |
| Camera | Simon Werry | Aerial Camera |
| Sound | Greg Zimmerman | Foley Recordist |
| Art | Gert Broekema | Property Master |
| Sound | Matt Colleran | Sound Recordist |
| Directing | Mark Taylor | Second Assistant Director |
| Crew | Gary Powell | Stunts |
| Costume & Make-Up | Barrie Gower | Prosthetic Makeup Artist |
| Lighting | Michael K. O'Melia | Assistant Chief Lighting Technician |
| Art | Leo Duranona | Storyboard Artist |
| Crew | Natasha Ivanova | Additional Dialogue |
| Camera | Kenny Groom | Assistant Camera |
| Art | TyRuben Ellingson | Concept Artist |
| Visual Effects | Ian Unterreiner | Visual Effects Production Assistant |
| Editing | Adam Glasman | Digital Colorist |
| Sound | Brian Basham | ADR Recordist |
| Camera | Alexander Bscheidl | Second Assistant Camera |
| Editing | Jim Garrow | Colorist |
| Production | Petr Brodsky | Extras Casting |
| Crew | Jan Beran | Special Effects Technician |
| Visual Effects | Lisa Bechard | Visual Effects Production Manager |
| Production | Vera Trousilová | Assistant Accountant |
| Production | Rob Seager | First Assistant Accountant |
| Costume & Make-Up | Jemma Scott-Knox-Gore | Contact Lens Technician |
| Camera | Chas Bain | Focus Puller |
| Visual Effects | Avtar Bains | Compositing Artist |
| Production | Alonzo Ruvalcaba | Head of Production |
| Directing | Martina Götthansova | Second Second Assistant Director |
| Sound | Nerses Gezalyan | Foley Mixer |
| Visual Effects | Clay Dale | CG Artist |
| Production | Ray Scalice | General Manager |
| Production | Cammeron Truesdale | Production Runner |
| Crew | Nikki Berwick | Stunt Double |
| Sound | Dave Jordan | Music Consultant |
| Camera | Darrel Griffin | Data Wrangler |
| Production | David Antol | Location Assistant |
| Production | Leon Dudevoir | Production Executive |
| Visual Effects | Dan Feinstein | Rotoscoping Artist |
| Editing | Josh Campbell | Assistant Editor |
| Production | Betty Burkhart | Post Production Coordinator |
| Production | Tyler Ham | Production Assistant |
| Sound | Jim Ervin | Music Producer |
| Crew | John Bannister | Key Scenic Artist |
| Sound | Ron Bedrosian | ADR Mixer |
| Production | Jennifer Hunt Pedevilla | Payroll Accountant |
| Visual Effects | Ray McIntyre Jr. | Visual Effects Supervisor |
| Crew | 甄子丹 | Martial Arts Choreographer |
| Directing | Gregory Palmer | Second Assistant Director |
