Frank Adler is een vrijgezel die zijn hoogbegaafde nichtje, Mary genaamd, opvoedt in een kustplaatsje in Florida. Frank probeert ervoor te zorgen dat Mary een normaal leven kan leiden. Zijn plannen worden gedwarsboomd als zijn moeder de wiskundige talenten van het meisje ontdekt en plannen maakt om Frank en Mary uit elkaar te halen.
| Directing | Marc Webb | Director |
| Writing | Tom Flynn | Writer |
| Production | Andy Cohen | Producer |
| Production | Karen Lunder | Producer |
| Editing | Bill Pankow | Editor |
| Sound | Tom Brown | Music Arranger |
| Camera | Stuart Dryburgh | Director of Photography |
| Production | David Rubin | Casting |
| Sound | Rob Simonsen | Original Music Composer |
| Art | Laura Fox | Production Design |
| Costume & Make-Up | Abby O'Sullivan | Costume Design |
| Production | Ben Browning | Executive Producer |
| Directing | Michael J. Leone | Script Supervisor |
| Production | Glen Basner | Executive Producer |
| Production | Molly Allen | Executive Producer |
| Art | Patrick Fuhrman | Leadman |
| Sound | Timothy Cargioli | Boom Operator |
| Crew | Max Calder | Stunts |
| Crew | Yan Dron | Stunts |
| Costume & Make-Up | Tiffany Lord | Hairstylist |
| Sound | Jesse Dodd | ADR Mixer |
| Sound | Mitch Dorf | ADR Mixer |
| Crew | Laurence Chavez | Stunts |
| Costume & Make-Up | Valerie Patterson | Makeup Artist |
| Sound | Bobby Johanson | ADR Mixer |
| Sound | Michael Miller | ADR Mixer |
| Costume & Make-Up | Andrea Bowman | Key Hair Stylist |
| Costume & Make-Up | Joan Shay | Hairstylist |
| Sound | Marissa Littlefield | ADR Editor |
| Production | T.K. Knowles | Associate Producer |
| Production | John O'Grady | Associate Producer |
| Production | Chuck Ryant | Associate Producer |
| Art | Charles Varga | Art Direction |
| Crew | Paul A. Levin | Post Production Supervisor |
| Sound | Ron Bochar | Supervising Sound Editor |
| Sound | Marko Costanzo | Foley Artist |
| Crew | Chick Bernhard | Stunts |
| Costume & Make-Up | Rita Parillo | Hair Department Head |
| Art | Douglas G. Young | Assistant Property Master |
| Crew | Rosie Bernhard | Stunts |
| Crew | Nick DeKay | Stunt Double |
| Sound | Philip Stockton | Dialogue Editor |
| Sound | Sara Stern | Dialogue Editor |
| Art | Justin Nathaniel Kistler | Art Department Coordinator |
| Sound | Paul Hsu | Sound Effects Editor |
| Sound | Sarah Streit | Assistant Sound Editor |
| Sound | Steven Visscher | Foley Editor |
| Costume & Make-Up | Susan Ransom | Key Makeup Artist |
| Production | Molly Allen | Unit Production Manager |
| Directing | Mark C. Stevens | Second Assistant Director |
| Sound | Patrick Christensen | ADR Mixer |
| Sound | Nick Jimenez | ADR Recordist |
| Sound | Todd Kasow | Music Editor |
| Art | Vera Mills | Set Decoration |
| Costume & Make-Up | J.C. Davis | Hairstylist |
| Crew | Eduardo Marques de Oliveira Jr. | Stunts |
| Crew | Deven MacNair | Stunts |
| Camera | Kane Pearson | Second Assistant "B" Camera |
| Crew | Lois Yaroshefsky | Studio Teacher |
| Camera | Chris Koch | Dolly Grip |
| Crew | Kevin R. Stephens | Set Medic |
| Camera | Michael Paul Jones | Camera Operator |
| Costume & Make-Up | Gina Ruiz | Assistant Costume Designer |
| Crew | Raymond Talley | Carpenter |
| Art | Scott B. Warner | Construction Foreman |
| Sound | George A. Lara | Foley Mixer |
| Crew | Keith Adams | Stunt Coordinator |
| Crew | Jeff Medeiros | Stunts |
| Lighting | Thomas H. Dean | Best Boy Electric |
| Camera | E.J. Misisco | First Assistant "A" Camera |
| Costume & Make-Up | Nico Sohn | Makeup Artist |
| Production | Peggy Robinson | Production Supervisor |
| Art | Scott D. Warner | Construction Coordinator |
| Crew | Stephen Conroy | Stunts |
| Lighting | Robyn Greer | Rigging Grip |
| Sound | Randall Poster | Music Supervisor |
| Crew | Margaret King | Set Medic |
| Crew | Mary Ann Lynah | Studio Teacher |
| Costume & Make-Up | Michal Bigger | Makeup Department Head |
| Directing | Jon Mallard | First Assistant Director |
| Art | Gillian Albinski | Property Master |
| Crew | E. Paul Anderson | Prop Maker |
| Sound | Jason Chiodo | Sound Re-Recording Mixer |
| Camera | T. Daniel Scaringi | Key Grip |
| Sound | Tony Kiernan | ADR Recordist |
| Crew | Adam S. Katz | Stunts |
| Crew | Bruce Cheek | Set Medic |
| Sound | Dave Wilson | ADR Mixer |
| Sound | Meghan Currier | Music Supervisor |
| Camera | John S. Moyer | Steadicam Operator |
| Camera | Tim Rook | Dolly Grip |
| Production | Bass Hampton | Location Manager |
| Art | Steven P. Brown | Painter |
| Visual Effects | Eran Dinur | Visual Effects Supervisor |
| Camera | Richard Henkels | Camera Operator |
| Production | Heather Neeld | Production Coordinator |
| Costume & Make-Up | Suzy Freeman | Costume Supervisor |
| Editing | Misako Shimizu | First Assistant Editor |
| Crew | Kevin LaRosa Jr. | Stunts |
| Lighting | Keith 'Zoot' Byrne | Gaffer |
| Camera | Wilson Webb | Still Photographer |
| Production | Melissa Pryor | Casting Associate |
| Production | Phil LoGrippo | Production Accountant |
| Crew | Trey Gordon | Special Effects Coordinator |
