Het verhaal speelt zich af in de kringen van de hippe, rijke jongeren in New York. White Mike is een jonge wannabe drugsdealer die stopt met zijn privé-school in de upper east side en zich volledig stort op zijn handeltje. Hij rookt en drinkt niet, maar bezoekt de feestjes enkel om zijn nieuwe drug 'twelve' te verkopen. Er ontstaan grote problemen voor Mike als zijn neef Charlie op straat wordt vermoord en zijn beste vriend wordt opgepakt als de dader.
Nee, helaas is Twelve nog niet beschikbaar op Netflix in Nederland.
| Directing | Joel Schumacher | Director |
| Writing | Jordan Melamed | Writer |
| Crew | Aaron Vexler | Stunt Driver |
| Production | Vanessa Hope | Associate Producer |
| Writing | Nick McDonell | Novel |
| Production | Charlie Corwin | Producer |
| Production | Sidonie Dumas | Producer |
| Production | Ted Field | Producer |
| Production | Jordan Melamed | Producer |
| Production | Robert Salerno | Producer |
| Camera | Steven Fierberg | Director of Photography |
| Editing | Gordon Grinberg | Editor |
| Editing | Paul Zucker | Editor |
| Production | Lauren Bass | Casting |
| Production | Jessica Kelly | Casting |
| Production | Suzanne Smith Crowley | Casting |
| Art | Ethan Tobman | Production Design |
| Art | Cherish M. Hale | Set Decoration |
| Costume & Make-Up | David C. Robinson | Costume Design |
| Production | Jordan Bass | Casting Associate |
| Costume & Make-Up | Matthew Simonelli | Assistant Costume Designer |
| Costume & Make-Up | Susan Wachsler | Costume Supervisor |
| Directing | Sharon Watt | Script Supervisor |
| Crew | Ryan Washburn | Armorer |
| Costume & Make-Up | Colleen Callaghan | Hair Department Head |
| Costume & Make-Up | Joseph Whitmeyer | Key Hair Stylist |
| Costume & Make-Up | Evelyne Noraz | Makeup Department Head |
| Crew | Conrad V. Brink Jr. | Special Effects Coordinator |
| Visual Effects | Joseph DiValerio | Visual Effects |
| Sound | Harry Gregson-Williams | Original Music Composer |
| Camera | Myles Aronowitz | Still Photographer |
| Sound | Richard Mader | Sound Mixer |
| Sound | Sean Garnhart | Sound Designer |
| Sound | Sean Garnhart | Sound Re-Recording Mixer |
| Sound | Sean Garnhart | Supervising Sound Editor |
| Sound | Tony Volante | Sound Re-Recording Mixer |
| Directing | Steve Apicella | First Assistant Director |
| Sound | Fred Rosenberg | Dialogue Editor |
| Sound | Steve Giammaria | Sound Recordist |
| Sound | Marissa Littlefield | ADR Editor |
