De in Pakistaan geboren Kumail heeft een relatie met een Amerikaanse vrouw, Emily. Samen moet ze de verwachtingen zien te overwinnen van zijn familie en hun 1400 jaar oude tradities. Zijn ouders blijven hem onophoudelijk bestoken met potentiële bruiden voor een gearrangeerd huwelijk.
Nee, helaas is The Big Sick nog niet beschikbaar op Netflix in Nederland.
| Crew | Joe Schultz | Driver |
| Sound | Tara A. Paul | Sound Re-Recording Mixer |
| Production | Barry Mendel | Producer |
| Directing | Michael Showalter | Director |
| Production | Judd Apatow | Producer |
| Costume & Make-Up | Sarah Mae Burton | Costume Designer |
| Writing | Kumail Nanjiani | Screenplay |
| Writing | Emily V. Gordon | Screenplay |
| Production | Jeremy Kipp Walker | Executive Producer |
| Art | Brandon Tonner-Connolly | Production Design |
| Camera | Brian Burgoyne | Director of Photography |
| Editing | Robert Nassau | Editor |
| Sound | Michael Andrews | Original Music Composer |
| Art | Lauren J. Brown | Property Master |
| Art | William Smith | Set Dresser |
| Production | Amanda Glaze | Co-Producer |
| Production | Ben Browning | Executive Producer |
| Costume & Make-Up | Christina Nickas | Wardrobe Supervisor |
| Production | Glen Basner | Executive Producer |
| Production | Jeremy Kipp Walker | Unit Production Manager |
| Camera | Anthony F. Gamiello | Grip |
| Art | Elizabeth Rodrick | Set Decoration |
| Art | Anthony Taratunio | Set Dresser |
| Production | Annie Tan | Production Supervisor |
| Production | Gayle Keller | Casting |
| Camera | Nicole Rivelli | Still Photographer |
| Camera | Sally Foster | Grip |
| Costume & Make-Up | Lauren Colbert | Costume Coordinator |
| Directing | Adam J. Bernard | Second Assistant Director |
| Production | Emily V. Gordon | Executive Producer |
| Camera | Brent Poleski | Key Grip |
| Camera | Larhn Laurens Davitt | Dolly Grip |
| Lighting | Jason Velez | Gaffer |
| Art | Andy Eklund | Art Direction |
| Art | Bill C. Bishop | Leadman |
| Costume & Make-Up | Megan Sanders | Wardrobe Supervisor |
| Production | Kumail Nanjiani | Executive Producer |
| Crew | Jeremy Sample | Stunt Coordinator |
| Camera | Yousheng Tang | Steadicam Operator |
| Costume & Make-Up | Maeve Kelly | Assistant Costume Designer |
| Art | Richard Hebrank | Construction Coordinator |
| Art | Anthony S. Calypso | Assistant Property Master |
| Camera | Pierrot Colonna | Camera Operator |
| Camera | Htat Htut | First Assistant Camera |
| Lighting | Francesco Pinna | Best Boy Electric |
| Directing | Nicholas Bell | First Assistant Director |
| Camera | Andrew Juhl | First Assistant Camera |
| Art | Shane Aitchison | Art Department Coordinator |
| Camera | Frank Larson | Camera Operator |
| Camera | Nuno Oliveira | Grip |
| Camera | Parissh McClean | Grip |
| Sound | Joe Rudge | Music Supervisor |
| Camera | Fillip Penson | First Assistant Camera |
| Camera | Cliff Alphonse | Grip |
| Directing | Mariana Hellmund | Script Supervisor |
| Camera | Ari Issler | Camera Operator |
| Art | Jack Mortellaro Jr. | Leadman |
| Crew | Adrienne Enderle | Set Production Assistant |
| Crew | Jocelyn Magsumbol | Production Office Assistant |
| Costume & Make-Up | Bert Reo Anderson | Hairstylist |
| Production | Johnny Holland | Production Accountant |
| Crew | Brad Gage | Actor's Assistant |
| Crew | George Holtzer | Transportation Captain |
| Crew | Mike Devereaux | Driver |
| Crew | Michael Jackman | Post Production Supervisor |
| Camera | Alec Jarnagin | Steadicam Operator |
| Costume & Make-Up | Kirsten Sylvester | Key Makeup Artist |
| Crew | Matt Merksamer | Set Production Assistant |
| Crew | Alex Lilja | Set Production Assistant |
| Crew | Bob Papini JR | Driver |
| Sound | Bobby Mackston | Sound Editor |
| Sound | Dan Edelstein | ADR Editor |
| Production | Nicki Slack | Assistant Production Coordinator |
| Visual Effects | Fangge Chen | Digital Compositors |
| Visual Effects | Melissa Kivell | VFX Production Coordinator |
| Sound | Pam DeMetruis-Thomas | Foley Editor |
| Crew | Jeff Brink | Special Effects Coordinator |
| Sound | Jerry 'Niru' Cox | Boom Operator |
| Sound | Paul Reed | Utility Sound |
| Crew | Lauren Meckleberg | Set Production Intern |
| Crew | Mike Murphy | Driver |
| Crew | Damon Tragni | Driver |
| Production | Cynthia Chou | Production Coordinator |
| Crew | Matthew McCoubry | Set Production Assistant |
| Crew | Anthony Pennachio | Set Production Assistant |
| Crew | Alex Spear | Set Production Assistant |
| Crew | Peter Link | Driver |
| Art | Aaron Becker | Title Designer |
| Crew | Yadeed Mellman | Set Production Assistant |
| Crew | Ava Myint | Set Production Intern |
| Crew | Ella Gibney | Set Production Intern |
| Visual Effects | Saffia Rahimtoola | Digital Compositors |
| Costume & Make-Up | Leo Won | Makeup Department Head |
| Crew | Ed Elliot | Driver |
| Crew | Roberto González Arévalo | Production Office Assistant |
| Crew | PJ Ford | Driver |
| Visual Effects | Neal Jones | Visual Effects |
| Production | Nicole P. Hearon | Casting Associate |
| Crew | Ryan Murphy | Driver |
| Sound | Tom Paul | Sound Re-Recording Mixer |
| Costume & Make-Up | Raquel Vivve | Makeup Artist |
| Costume & Make-Up | Tonia Ciccone | Hair Department Head |
| Crew | Jasmine Brotzman | Set Production Assistant |
| Sound | Mark Linden | Sound Re-Recording Mixer |
| Sound | Azniv Korkejian | Music Editor |
| Production | Allison Kirschner | Casting Associate |
| Production | Aaron Schoonover | Casting Associate |
| Sound | Tom Paul | Supervising Sound Editor |
| Sound | Sean Garnhart | Sound Effects Editor |
| Production | Bruce Winant | ADR Voice Casting |
| Visual Effects | Lucien Harriot | VFX Supervisor |
| Sound | Junior Cyrus Baron | Utility Sound |
| Costume & Make-Up | Josh Gericke | Hairstylist |
| Crew | Jon Santo | Set Production Assistant |
| Crew | Liz Wagner | Set Production Assistant |
| Crew | Isaac Gotterer | Set Production Intern |
| Editing | Luis Cuevas | Assistant Editor |
| Editing | Leah Tuscano | Assistant Editor |
| Production | Jillian Stricker | Location Manager |
| Costume & Make-Up | Toni Roman-Grimm | Key Hair Stylist |
| Crew | Robert Maasin | Set Production Assistant |
| Crew | Mike Mcelroy | Driver |
| Production | Dann Fink | ADR Voice Casting |
| Sound | Bill Orrico | Dialogue Editor |
| Visual Effects | Constance Conrad | Digital Compositors |
| Production | Adam Kersh | Publicist |
| Sound | Charles R. Hunt | Production Sound Mixer |
| Editing | Zach Wolf | Assistant Editor |
| Crew | Michael Elliott | Transportation Co-Captain |
