Jazzzangeres Lucia heeft het sinds haar scheiding helemaal gehad met mannen. Haar eveneens gescheiden vriendin Maria, moeder van twee kinderen, kan er echter niet genoeg van krijgen. Vrijwel dagelijks gaat zij op zoek naar een man om de nacht mee door te brengen. Op een morgen treft Lucia in het appartement van Maria, op het moment dat die even om een boodschap is, de naakte jongeman Luca. Omdat die zich niets meer kan herinneren van de afgelopen avond en nacht denkt Luca dat Lucia degene is met wie hij het bed heeft gedeeld. Het begin van een reeks misverstanden met verstrekkende gevolgen.
Nee, helaas is Qualcosa di nuovo nog niet beschikbaar op Netflix in Nederland.
| Production | Giuseppe Pugliese | Production Manager |
| Production | Camilla Bramini | Unit Manager |
| Art | Marinella Perrotta | Set Decoration |
| Visual Effects | Paola Trisoglio | Visual Effects Producer |
| Camera | Stefano Paradiso | Steadicam Operator |
| Art | Maria Grazia Schirripa | Assistant Production Design |
| Sound | Luca Anzellotti | Sound Effects |
| Sound | Stefania Anzellotti | Sound Effects |
| Writing | Cristina Comencini | Theatre Play |
| Directing | Francesca Polic Greco | First Assistant Director |
| Directing | Luca Padrini | Second Assistant Director |
| Production | Luigi Napoleone | Executive Producer |
| Sound | Vincenzo Nardi | Boom Operator |
| Costume & Make-Up | Ermanno Spera | Makeup Department Head |
| Directing | Ilaria Schipa | Second Assistant Director |
| Camera | Fabrizio Vicari | Camera Operator |
| Production | Giovanni Stabilini | Producer |
| Camera | Italo Petriccione | Director of Photography |
| Editing | Francesca Calvelli | Editor |
| Crew | Simona De Laurentiis | Post Production Supervisor |
| Production | Alice Marchitelli | Location Manager |
| Camera | Stefano Paradiso | Camera Operator |
| Production | Francesca Longardi | Delegated Producer |
| Writing | Cristina Comencini | Story |
| Production | Massimo Di Rocco | Executive Producer |
| Sound | Attilio Gizzi | Sound Effects |
| Production | Tea Cappiello | Production Coordinator |
| Production | Laura Muccino | Casting |
| Visual Effects | Stefano Marinoni | VFX Supervisor |
| Costume & Make-Up | Francesca Sartori | Costume Design |
| Directing | Cinzia Malatesta | Script Supervisor |
| Sound | Andrea Caretti | Sound Editor |
| Camera | Gian Claudio Giacomini | Assistant Camera |
| Editing | Stefano Mariotti | Assistant Editor |
| Costume & Make-Up | Teresa Di Serio | Hair Department Head |
| Camera | Claudio Palmieri | Assistant Camera |
| Sound | Francesco Tumminello | Sound Mixer |
| Production | Arianna De Chiara | Delegated Producer |
| Art | Paola Comencini | Production Design |
| Sound | Maurizio Argentieri | Sound |
| Production | Marco Chimenz | Producer |
| Writing | Giulia Calenda | Story |
| Writing | Paola Cortellesi | Story |
| Production | Lorenzo Battisti | Unit Manager |
| Sound | Jacopo Anzellotti | Sound Effects |
| Sound | Luciano Anzellotti | Sound Effects |
| Camera | Massimo Barbona | Key Grip |
| Sound | Dario Pasquale | Sound Effects |
| Lighting | Marco Sticchi | Gaffer |
| Sound | Massimo Anzellotti | Sound Effects |
| Writing | Paola Cortellesi | Screenplay |
| Directing | Cristina Comencini | Director |
| Production | Riccardo Tozzi | Producer |
| Sound | Andrea Farri | Original Music Composer |
| Writing | Giulia Calenda | Screenplay |
| Writing | Cristina Comencini | Screenplay |
