Jazzzangeres Lucia heeft het sinds haar scheiding helemaal gehad met mannen. Haar eveneens gescheiden vriendin Maria, moeder van twee kinderen, kan er echter niet genoeg van krijgen. Vrijwel dagelijks gaat zij op zoek naar een man om de nacht mee door te brengen. Op een morgen treft Lucia in het appartement van Maria, op het moment dat die even om een boodschap is, de naakte jongeman Luca. Omdat die zich niets meer kan herinneren van de afgelopen avond en nacht denkt Luca dat Lucia degene is met wie hij het bed heeft gedeeld. Het begin van een reeks misverstanden met verstrekkende gevolgen.
Nee, helaas is Qualcosa di nuovo nog niet beschikbaar op Netflix in Nederland.
| Costume & Make-Up | Francesca Sartori | Costume Design |
| Camera | Italo Petriccione | Director of Photography |
| Production | Camilla Bramini | Unit Manager |
| Crew | Simona De Laurentiis | Post Production Supervisor |
| Production | Alice Marchitelli | Location Manager |
| Sound | Luca Anzellotti | Sound Effects |
| Visual Effects | Stefano Marinoni | VFX Supervisor |
| Art | Paola Comencini | Production Design |
| Sound | Francesco Tumminello | Sound Mixer |
| Costume & Make-Up | Teresa Di Serio | Hair Department Head |
| Camera | Claudio Palmieri | Assistant Camera |
| Sound | Jacopo Anzellotti | Sound Effects |
| Directing | Cinzia Malatesta | Script Supervisor |
| Art | Marinella Perrotta | Set Decoration |
| Production | Giovanni Stabilini | Producer |
| Production | Arianna De Chiara | Delegated Producer |
| Costume & Make-Up | Ermanno Spera | Makeup Department Head |
| Camera | Massimo Barbona | Key Grip |
| Production | Marco Chimenz | Producer |
| Camera | Stefano Paradiso | Steadicam Operator |
| Directing | Francesca Polic Greco | First Assistant Director |
| Production | Lorenzo Battisti | Unit Manager |
| Directing | Luca Padrini | Second Assistant Director |
| Production | Giuseppe Pugliese | Production Manager |
| Directing | Ilaria Schipa | Second Assistant Director |
| Writing | Cristina Comencini | Theatre Play |
| Sound | Luciano Anzellotti | Sound Effects |
| Sound | Attilio Gizzi | Sound Effects |
| Writing | Giulia Calenda | Story |
| Writing | Paola Cortellesi | Story |
| Sound | Andrea Caretti | Sound Editor |
| Editing | Stefano Mariotti | Assistant Editor |
| Lighting | Marco Sticchi | Gaffer |
| Production | Massimo Di Rocco | Executive Producer |
| Sound | Maurizio Argentieri | Sound |
| Sound | Massimo Anzellotti | Sound Effects |
| Production | Francesca Longardi | Delegated Producer |
| Writing | Cristina Comencini | Story |
| Production | Laura Muccino | Casting |
| Production | Luigi Napoleone | Executive Producer |
| Production | Tea Cappiello | Production Coordinator |
| Camera | Gian Claudio Giacomini | Assistant Camera |
| Art | Maria Grazia Schirripa | Assistant Production Design |
| Visual Effects | Paola Trisoglio | Visual Effects Producer |
| Editing | Francesca Calvelli | Editor |
| Camera | Fabrizio Vicari | Camera Operator |
| Camera | Stefano Paradiso | Camera Operator |
| Sound | Vincenzo Nardi | Boom Operator |
| Sound | Dario Pasquale | Sound Effects |
| Sound | Stefania Anzellotti | Sound Effects |
| Directing | Cristina Comencini | Director |
| Writing | Paola Cortellesi | Screenplay |
| Writing | Giulia Calenda | Screenplay |
| Production | Riccardo Tozzi | Producer |
| Writing | Cristina Comencini | Screenplay |
| Sound | Andrea Farri | Original Music Composer |
