Op een Halloween-avond rijden Cindy Campbell en vijf vrienden per ongeluk een man aan. Ze besluiten om het ongeluk geheim te houden, maar een jaar later wordt het zestal achterna gezeten door een gemaskerde seriemoordenaar, die wrede spelletjes met hen wil spelen. Het begint bij de brute moord op Drew Decker en het duurt niet lang voor de moordenaar achter Cindy en de rest aangaat. Deze zetten alles op alles om te overleven, maar de moordenaar geeft niet makkelijk op; hij heeft namelijk een behoorlijke grote kennis op het gebied van horrorfilms.
| Directing | Keenen Ivory Wayans | Director |
| Writing | Shawn Wayans | Screenplay |
| Writing | Buddy Johnson | Screenplay |
| Writing | Phil Beauman | Screenplay |
| Writing | Jason Friedberg | Screenplay |
| Production | Eric L. Gold | Producer |
| Production | Keenen Ivory Wayans | Producer |
| Production | Marlon Wayans | Producer |
| Production | Shawn Wayans | Producer |
| Editing | Mark Helfrich | Editor |
| Production | Denise Doyle | Casting |
| Production | Anne McCarthy | Casting |
| Production | Christine Sheaks | Casting |
| Production | Mary Vernieu | Casting |
| Art | Lawrence F. Pevec | Art Direction |
| Art | Louise Roper | Set Decoration |
| Costume & Make-Up | Darryle Johnson | Costume Design |
| Writing | Aaron Seltzer | Screenplay |
| Writing | Marlon Wayans | Screenplay |
| Production | Lee R. Mayes | Producer |
| Sound | Bruce Fortune | Dialogue Editor |
| Production | Lisa Blum | Co-Producer |
| Production | Cary Granat | Executive Producer |
| Production | Brad Grey | Executive Producer |
| Production | Robb Wilson King | Associate Producer |
| Production | Peter Safran | Executive Producer |
| Production | Peter Schwerin | Executive Producer |
| Production | Bob Weinstein | Executive Producer |
| Production | Harvey Weinstein | Executive Producer |
| Production | Bo Zenga | Executive Producer |
| Sound | David Kitay | Original Music Composer |
| Crew | Leslie McMichael | Stunts |
| Crew | Doug Chapman | Stunts |
| Crew | J.J. Makaro | Stunt Coordinator |
| Camera | Francis Kenny | Director of Photography |
| Art | Robb Wilson King | Production Design |
| Directing | Madeleine Duff | Script Supervisor |
| Camera | Chris Large | Still Photographer |
| Camera | David Crone | Steadicam Operator |
| Camera | David Crone | Camera Operator |
| Camera | Jim Van Dijk | Steadicam Operator |
| Art | Laura Hopkins | Art Department Coordinator |
| Art | David Hay | Assistant Art Director |
| Art | Clare Davis | Construction Coordinator |
| Art | Gary McVarish | Construction Foreman |
| Art | Arthur A. Green | Greensman |
| Art | David Beetham | Lead Painter |
| Art | Ken Hovgaard | Location Scout |
| Art | Marcus Endean | Production Illustrator |
| Camera | Greg Beaton | First Assistant Camera |
| Costume & Make-Up | Jana MacDonald | Assistant Costume Designer |
| Costume & Make-Up | Michelle Baines | Costume Supervisor |
| Costume & Make-Up | Angelina P. Cameron | Hair Department Head |
| Costume & Make-Up | Linda Villalobos | Hairstylist |
| Costume & Make-Up | Stan Edmonds | Makeup Department Head |
| Costume & Make-Up | Corey Adams | Prosthetic Supervisor |
| Costume & Make-Up | Andre Brouwer | Set Costumer |
| Costume & Make-Up | Stacey Butterworth | Wigmaker |
| Crew | Callum Simcoe | Carpenter |
| Crew | Gordon Wise | Chef |
| Crew | Cathy Cunliffe | Craft Service |
| Crew | Brad Kuehn | Digital Effects Supervisor |
| Crew | Donald Frank Bush | Driver |
| Crew | Holland Miller | Makeup Effects |
| Crew | Rob Summers | Post Production Assistant |
| Crew | Ninon Tantet | Post Production Supervisor |
| Crew | John B. Keys | Scenic Artist |
| Crew | Gordon Juli | Security |
| Crew | Gary Paller | Special Effects Coordinator |
| Crew | Brett Armstrong | Stunts |
| Crew | Carl J. Janssen | Transportation Co-Captain |
| Crew | Dennis Houser | Transportation Coordinator |
| Production | Lee R. Mayes | Unit Production Manager |
| Crew | Cara Leibovitz | Unit Publicist |
| Editing | Dennis McNeill | Color Timer |
| Lighting | Vance Vegas Salvalaggio | Lighting Technician |
| Lighting | Ken W. Anderson | Rigging Gaffer |
| Production | Daniel R. Chavez | Executive In Charge Of Post Production |
| Production | Kevin Hyman | Executive In Charge Of Production |
| Production | Ed Nesling | Location Manager |
| Production | Cheryl Kurk | Production Accountant |
| Production | Sandra Palmer | Production Coordinator |
| Sound | Graham Crowell | Boom Operator |
| Sound | Terry Wilson | Music Editor |
| Sound | Michael Dilbeck | Music Supervisor |
| Sound | Don Nemitz | Orchestrator |
| Sound | Dan Wallin | Scoring Mixer |
| Sound | Sandy Berman | Sound Designer |
| Sound | Anthony Milch | Sound Editor |
| Sound | Steve Mann | Sound Effects Editor |
| Sound | John Leveque | Supervising Sound Editor |
| Visual Effects | Steward Burris | 3D Supervisor |
| Visual Effects | Peter Koczera | Digital Compositors |
| Visual Effects | Mara Hamilton | Visual Effects Producer |
| Visual Effects | Brian Jennings | Visual Effects Supervisor |
| Writing | Jim Coombs | Storyboard |
| Production | Janice Frome | Unit Manager |
| Art | Clive Edwards | Property Master |
| Sound | Richard Lightstone | Production Sound Mixer |
| Art | Chad W. Chilibeck | Assistant Set Dresser |
| Art | Alfio Berardo | Assistant Property Master |
| Art | Paul Jenkinson | Lead Set Dresser |
| Art | J.P. Bagshaw | Set Dresser |
| Art | Peter Koczera | Title Designer |
| Camera | James Salberg | Dolly Grip |
| Camera | Al Campbell | Key Grip |
| Camera | Ben Rusi | Grip |
| Costume & Make-Up | Stan Edmonds | Key Makeup Artist |
| Directing | Michael Waxman | First Assistant Director |
| Directing | Suzan Derkson | Second Assistant Director |
| Directing | Jeff Mosuk | Third Assistant Director |
| Lighting | Dennis Brock | Chief Lighting Technician |
| Production | Barbara Harris | ADR Voice Casting |
| Production | Anna-Marie Plosz | Assistant Production Coordinator |
| Production | Rachael Erwin | Casting Assistant |
| Sound | Becky Sullivan | ADR Editor |
| Sound | Meredith Gold | Assistant Sound Editor |
| Sound | Shawn Sykora | Foley Editor |
| Sound | Lee Lemont | Supervising ADR Editor |
| Sound | Charles Martin Inouye | Supervising Music Editor |
| Sound | Steve Kohler | Sound Recordist |
| Directing | Mark Hansson | First Assistant Director (Prep) |
| Sound | Brian Best | Apprentice Sound Editor |
| Costume & Make-Up | Tone Rorvik | Assistant Makeup Artist |
| Costume & Make-Up | Robert Jezsik | Costume Set Supervisor |
| Directing | William D. Robinson | Second Second Assistant Director |
| Directing | J.J. Makaro | Second Unit Director |
| Art | Richard H. Fahlman | Construction Buyer |
| Sound | Robin Harlan | Foley Artist |
| Sound | Randy Singer | Foley Mixer |
| Crew | Steve Davis | Special Effects Assistant |
| Crew | Jovan Nenadic | Stunt Double |
| Camera | Attila Luca | Assistant Camera |
| Camera | Matt Almas | Best Boy Grip |
| Camera | Artino Ahmadi | Camera Trainee |
| Camera | Drew David | Dolly Grip |
| Camera | Dean Hannas | Second Assistant Camera |
| Production | Jina Johnson | Assistant Extras Casting |
| Editing | Cheryl Buckman | Assistant Editor |
| Editing | Michael Healey | Colorist |
| Production | Terry Mialkowsky | Assistant Location Manager |
| Production | Jon Raitt | Location Assistant |
| Sound | David Kitay | Conductor |
| Sound | Bryan Bonwell | Music Consultant |
| Production | Heather Trimble | Assistant Accountant |
| Crew | Diane Fatiaki | Assistant Chef |
| Production | Andrea Brown | Extras Casting |
| Production | Anil Patadé | First Assistant Accountant |
| Crew | Roger Bailey | Generator Operator |
| Production | Brenda McClellan | Payroll Accountant |
| Production | Ashley Bell | Production Assistant |
