John Rambo is met pensioen en woont op een boerderij in de Verenigde Staten. Op een dag hoort hij van Maria, een oude familievriendin en vastgoedmanager, dat zijn dochter is ontvoerd door een Mexicaans drugskartel. Al snel komt John terecht in de gewelddadige wereld van de sekshandel. Hij werkt samen met een journalist, wiens halfzus ook is ontvoerd, en moet al zijn vaardigheden inzetten om de meisjes te redden en een kwaadaardige misdaadbaas neer te halen.
Ja! de film Rambo: Last Blood is nu beschikbaar om te kijken op Netflix in Nederland.
| Crew | Dessy Slavova | Stunt Double |
| Crew | Radka Petkova | Stunts |
| Writing | Matthew Cirulnick | Screenplay |
| Writing | Sylvester Stallone | Screenplay |
| Production | Avi Lerner | Producer |
| Production | Kevin King Templeton | Producer |
| Production | Ariel Vromen | Executive Producer |
| Production | Lati Grobman | Executive Producer |
| Production | Christa Campbell | Executive Producer |
| Directing | Adrian Grünberg | Director |
| Art | David Temprano | Art Direction |
| Sound | Kiril Kaloyanov | Boom Operator |
| Sound | Ryan Nowak | Sound Designer |
| Art | Eduardo Hidalgo Jr. | Art Direction |
| Sound | Vladimir Kaloyanov | Sound Mixer |
| Art | Franco-Giacomo Carbone | Production Design |
| Writing | David Morrell | Characters |
| Camera | Brendan Galvin | Director of Photography |
| Sound | Brian Tyler | Original Music Composer |
| Editing | Carsten Kurpanek | Editor |
| Editing | Todd E. Miller | Editor |
| Production | Yariv Lerner | Producer |
| Production | Allen Dam | Executive Producer |
| Production | Boaz Davidson | Executive Producer |
| Lighting | Konstantin Vladimirov | Gaffer |
| Production | Zhang Qun | Executive Producer |
| Production | Elijah Long | Co-Executive Producer |
| Crew | Georgi Manchev | Fight Choreographer |
| Art | Kess Bonnet | Supervising Art Director |
| Production | Jonathan Yunger | Executive Producer |
| Production | Valentin Dimitrov | Line Producer |
| Art | Emil Gigov | Art Direction |
| Visual Effects | Richard Van Den Bergh | Special Effects Supervisor |
| Production | Robert Van Norden | Executive Producer |
| Production | Matthew O'Toole | Executive Producer |
| Production | Victor Hadida | Co-Executive Producer |
| Directing | Charlie Watson | First Assistant Director |
| Production | Lonnie Ramati | Co-Executive Producer |
| Art | Valentina Mladenova | Set Decoration |
| Visual Effects | Aleksander Aleksiev | Visual Effects Supervisor |
| Production | Carla Hool | Casting |
| Directing | Paul Taylor | Second Assistant Director |
| Directing | Maralyn Causley | Script Supervisor |
| Production | Louis Arriola | Executive Producer |
| Costume & Make-Up | Cristina Sopeña | Costume Designer |
| Production | Vessela Bannzurkova | Unit Production Manager |
| Camera | Miroslav Borisov | Key Grip |
| Art | Nieves Monterde | Set Decoration |
| Sound | Tapio Liukkonen | Foley Artist |
| Production | Jeff Gum | Executive Producer |
| Directing | Vern Nobles | Second Unit Director |
| Production | Jiewen Tan | Executive Producer |
| Sound | Kris Casavant | Supervising Sound Editor |
| Production | Samuel Hadida | Co-Executive Producer |
| Production | Alberto Poveda Rey | Unit Production Manager |
| Crew | Cuco Usín | Stunt Coordinator |
| Production | Damaine Radcliff | Co-Executive Producer |
| Crew | Diyan Hristov | Stunt Coordinator |
| Sound | Boris Tanchev | Boom Operator |
| Visual Effects | Pau Costa | Special Effects Supervisor |
| Art | Dirk Buchmann | Property Master |
| Production | Les Weldon | Producer |
| Production | Jeffrey Greenstein | Executive Producer |
| Production | Liu Rong | Executive Producer |
| Lighting | Eduardo Camprubí | Electrician |
| Camera | Borislav Belberov | First Assistant Camera |
| Camera | Paula Nenova | First Assistant "B" Camera |
| Camera | Simon Varsano | Still Photographer |
| Costume & Make-Up | Yurena Cazorla | Makeup Artist |
| Production | Patricia Amor | Casting Associate |
| Camera | Rafael Rodriguez Lamas | Digital Imaging Technician |
| Camera | Dave Isern | Steadicam Operator |
| Production | Mark Sussman | ADR Voice Casting |
| Costume & Make-Up | Fernando García Brea | Assistant Costume Designer |
| Camera | Aleksandar Ribarski | Grip |
| Costume & Make-Up | Paula Barroso | Costumer |
| Costume & Make-Up | Gara Hamad | Costumer |
| Costume & Make-Up | Fionagh Cush | Makeup Artist |
| Production | Camilla-Valentine Isola | Casting |
| Costume & Make-Up | Katarina Pavlova | Costumer |
| Camera | Ivana Vladić | First Assistant Camera |
| Camera | Desislav Dimitrov | Grip |
| Lighting | Ognian Atanasov | Electrician |
| Camera | Biser Rulev | Grip |
| Costume & Make-Up | Jasmina Vasileva | Costume Supervisor |
| Camera | Ivan Vatsov | Camera Operator |
| Costume & Make-Up | Tiptalee Chanaputtakun | Hairstylist |
| Lighting | Héctor Gabriel García | Electrician |
| Camera | Ivailo Tzvetkov | First Assistant "A" Camera |
| Camera | Ivelin Metodiev | First Assistant "C" Camera |
| Crew | Vern Nobles | Second Unit Cinematographer |
| Costume & Make-Up | Desislava Manasieva | Makeup Artist |
| Production | Steven Paul | Producer |
| Camera | Ivo Velkov | Digital Imaging Technician |
| Camera | Dimitar Krustev | Drone Pilot |
| Costume & Make-Up | Ralitsa Roth | Makeup Artist |
| Production | Eliseo Ruiz | Casting Associate |
| Costume & Make-Up | Nuria Barrio | Set Costumer |
| Production | Cristina Santacreu | Extras Casting Assistant |
| Lighting | Sven Vohser | Electrician |
| Camera | Héctor Quintero Domínguez | Focus Puller |
| Production | Natalie Ballesteros | Casting Associate |
| Camera | Don Cherel | Camera Operator |
| Camera | Dawid Pietkiewicz | Camera Operator |
| Camera | Lyubomir Somov | First Assistant "A" Camera |
| Camera | Valentin Stanimirov | Grip |
| Costume & Make-Up | Daniela Avramova | Key Makeup Artist |
| Costume & Make-Up | Stephen Prouty | Prosthetic Designer |
| Camera | Des Whelan | Camera Operator |
| Camera | Luis Cesar Izquierdo | Focus Puller |
| Production | Hrista Ilieva | Extras Casting |
| Costume & Make-Up | Eva Fervenza | Costume Supervisor |
| Lighting | Daniel Arenas Cortes | Lighting Artist |
| Visual Effects | Aleksey Hrzhehorzhevskyi | Visual Effects Coordinator |
| Art | Evgeni Yordanov | Construction Manager |
| Art | Pavlina Petrova | Concept Artist |
| Crew | Diego Gortázar | CG Supervisor |
| Visual Effects | Alexander Kadim | Visual Effects Supervisor |
| Visual Effects | Łukasz Kołtunowicz | Visual Effects Producer |
| Visual Effects | Pedro Domingo Luque | Visual Effects Producer |
| Editing | Ivan Todorov Ivanov | Assistant Editor |
| Visual Effects | Dragostin Valev | Compositing Supervisor |
| Art | Joseph Díaz | Concept Artist |
| Visual Effects | Alice Olson-Coons | Visual Effects Coordinator |
| Visual Effects | Anna Rovira Macià | Visual Effects Production Manager |
| Visual Effects | Helena Holmes | Special Effects Supervisor |
| Visual Effects | Julia Manolova | Visual Effects Coordinator |
| Visual Effects | Kristian Talajic | Visual Effects Supervisor |
| Art | Orlando Harris | Graphic Designer |
| Editing | Bradley Greer | Digital Intermediate Colorist |
| Visual Effects | Magnus Olsson | 3D Artist |
| Visual Effects | Svetoslav Mitev | Visual Effects Coordinator |
| Visual Effects | Danail Hadzhiyski | Visual Effects Producer |
| Visual Effects | Andres Mas | Visual Effects Production Assistant |
| Art | Tatiana Urquiza | Art Department Assistant |
| Art | Anna Hadzhieva | Set Decorating Coordinator |
| Art | Nikolai Nikolov | Set Designer |
| Visual Effects | David Andreu | Animation |
| Art | Krista Vacheva | Storyboard Artist |
| Art | Marimar Lara | Standby Painter |
| Art | Cristina Acuña | Standby Painter |
| Editing | Damian F. Gomez | First Assistant Editor |
| Art | Neil D'Monte | Storyboard Artist |
| Editing | Nedelko Tudzharov | First Assistant Editor |
| Visual Effects | A. Martín Puentes | Animation Supervisor |
| Art | Nieves Monterde | Set Designer |
| Writing | Sylvester Stallone | Screenstory |
| Writing | Dan Gordon | Screenstory |
| Crew | Max Kraus | Stunts |
