Dennis en Steve zijn paramedici werkzaam in New Orleans. Ze stuiten op een reeks gruwelijke sterfgevallen die verband houden met een designerdrug. Er is nog maar weinig bekend over de drug die erg vreemde effecten bij de gebruikers veroorzaakt. Ook de vriendschap tussen de twee heren en de levens van hun familie worden door de drug aangetast.
| Costume & Make-Up | Chelsea Barber | Assistant Hairstylist |
| Costume & Make-Up | Chantelle Calmes | Assistant Hairstylist |
| Costume & Make-Up | Timothy Blackburn | Assistant Hairstylist |
| Costume & Make-Up | Courtney Marie Callais | Assistant Makeup Artist |
| Costume & Make-Up | Bailey Domke | Assistant Makeup Artist |
| Costume & Make-Up | Lesley Rodriguez | Assistant Makeup Artist |
| Costume & Make-Up | Claire Rav | Assistant Makeup Artist |
| Costume & Make-Up | LeDiedra Richard-Baldwin | Assistant Makeup Artist |
| Costume & Make-Up | Marcos Gonzales | Hair Department Head |
| Costume & Make-Up | Courtney Lether | Key Makeup Artist |
| Costume & Make-Up | Karri Farris | Makeup Department Head |
| Costume & Make-Up | Greg McDougall | Special Effects Makeup Artist |
| Art | Josh Crouchet | Art Department Coordinator |
| Art | Erik van Haaren | Construction Coordinator |
| Art | Kim Berens | Graphic Designer |
| Art | Hunter Spears | Leadman |
| Art | Billy Bamman | Property Master |
| Crew | Laurie Fewell | Scenic Artist |
| Camera | William Tanner Sampson | Camera Operator |
| Camera | Daniel Waghorne | Drone Pilot |
| Lighting | Carl Foreman | Electrician |
| Camera | Thomas Matheis | Epk Camera Operator |
| Camera | Penelope Helmer | First Assistant "A" Camera |
| Lighting | Sergio Villegas | Gaffer |
| Camera | Austin Kenyon | Grip |
| Camera | Reid Lauff | Grip |
| Camera | Michael L. Smith | Key Grip |
| Camera | Giovanni Bommarito | Dolly Grip |
| Camera | Patti Perret | Still Photographer |
| Costume & Make-Up | Caryn Frankenfield | Costume Supervisor |
| Costume & Make-Up | Mandy Pauline | Costume Supervisor |
| Costume & Make-Up | Alaina Boyett | Costumer |
| Costume & Make-Up | Tallie Adair Currier | Costumer |
| Costume & Make-Up | Tamika Jackson | Costumer |
| Costume & Make-Up | Amy Darden Amos | Seamstress |
| Costume & Make-Up | Taylor Price | Set Costumer |
| Art | Clay Rodery | Textile Artist |
| Directing | Ryan Orenstein | First Assistant Director |
| Directing | Jessica Dean Rose | Second Assistant Director |
| Sound | Shacora Mitchell | ADR Mixer |
| Sound | Michaela Girouard | Boom Operator |
| Sound | John Kirby Leonard | Boom Operator |
| Sound | Tom Boykin | Dialogue Editor |
| Sound | Ryan Maguire | Foley Mixer |
| Sound | Yahel Dooley | Sound Designer |
| Sound | Yahel Dooley | Sound Re-Recording Mixer |
| Sound | James Lucero | Sound Effects Editor |
| Sound | Blake Donaubauer | Sound Mixer |
| Crew | David K. Nami | Special Effects Coordinator |
| Visual Effects | Antoine Cosset | Visual Effects Producer |
| Visual Effects | Olivier Cauwet | Visual Effects Supervisor |
| Production | Meagan Lewis | Casting |
| Production | Theresa Hernandez | Casting Associate |
| Production | Lee Pierce | Extras Casting |
| Directing | Sandy Parker | Script Supervisor |
| Editing | Jennifer Raymond | Digital Intermediate Editor |
| Editing | Patrick M. Allen | Digital Intermediate Producer |
| Production | Meghan Russell | First Assistant Accountant |
| Production | Tamara Henderson | Production Accountant |
| Production | Rebecca Chulew | Production Assistant |
| Production | Lindsay D. Lyon | Production Assistant |
| Production | Des Matelske | Production Coordinator |
| Production | Megan Slater | Production Secretary |
| Visual Effects | Yann Austin | VFX Artist |
| Visual Effects | Liliane Chu | VFX Artist |
| Visual Effects | Charles Dizier | VFX Artist |
| Visual Effects | Lucile Jules Gaston | VFX Artist |
| Visual Effects | Aurélien Marquaille | VFX Artist |
| Visual Effects | Duy Anh Nguyen | VFX Artist |
| Visual Effects | Quentin Ramasseul | VFX Artist |
| Visual Effects | Nicolas Ndame | VFX Artist |
| Visual Effects | Angela Mikrut | VFX Artist |
| Crew | Dustin L. Bankston | Special Effects Technician |
| Crew | Jody Honold | Special Effects Technician |
| Crew | Collin Nami | Special Effects Technician |
| Crew | William Nami | Special Effects Technician |
| Art | Sam Hensen | Set Dresser |
| Art | Shea Creel | Set Dresser |
| Costume & Make-Up | Daisy McNairy | Costumer |
| Costume & Make-Up | Brik Allen | Truck Costumer |
| Costume & Make-Up | Aldo Katayanagi | Costume Illustrator |
| Crew | Andy Dylan | Stunt Coordinator |
| Crew | Tim Bell | Stunt Coordinator |
| Crew | Sean Paul Braud | Stunt Coordinator |
| Production | Leah Richard | Second Assistant Accountant |
| Production | Lindsey Page | Payroll Accountant |
| Production | Scottie Brower | Location Manager |
| Lighting | Cody Cefalu | Best Boy Electric |
| Lighting | Rob Wilson | Electrician |
| Lighting | Carlos Germain | Electrician |
| Lighting | James Williams | Electrician |
| Lighting | John Pitre | Rigging Gaffer |
| Lighting | Barry Williamson | Key Rigging Grip |
| Camera | Alyssa Moran | Grip |
| Camera | Charles Wiggins | Grip |
| Camera | Styles Cooper | Grip |
| Camera | Mike Nami Jr. | Grip |
| Camera | Khader Ahlerimi | Grip |
| Art | Anthony Chow | Property Master |
| Art | Adriane Bennett | Assistant Property Master |
| Art | Shelley Dall | Assistant Property Master |
| Crew | Mike Tveten | Prop Maker |
| Crew | Ashley Wetwiski | Prop Maker |
| Crew | James Brammer | Prop Maker |
| Crew | Rich Guilliot | Prop Maker |
| Crew | Kerry Brown | Prop Maker |
| Crew | Michael Dinwiddie | Prop Maker |
| Crew | Sam Ruchti | Special Effects Technician |
| Crew | Colby Roberson | Special Effects Technician |
| Crew | Jordan Nami | Special Effects Technician |
| Crew | JoJo Honold | Special Effects Technician |
| Crew | Alexis Richard | Set Production Assistant |
| Crew | Lisa Oppel | Set Production Assistant |
| Crew | Stacy Brewer | Set Production Assistant |
| Crew | Jennifer Guedon | Set Production Assistant |
| Crew | Charlotte Molony | Set Production Assistant |
| Crew | Andrew Landry | Set Production Assistant |
| Crew | Andy Bolas | Set Production Assistant |
| Crew | Rebecca Challen | Set Production Assistant |
| Crew | Ethan Esteb | Set Production Assistant |
| Crew | Lauren Ewell | Set Production Assistant |
| Crew | Sid Yost | Animal Coordinator |
| Crew | Nathan Engel | Animal Wrangler |
| Sound | Joan Rowe | Foley Artist |
| Sound | Lyndsey Schenk | Foley Editor |
| Sound | Kyle Lane | ADR Mixer |
| Sound | Jon Vogl | ADR Mixer |
| Sound | Rob Searle | ADR Mixer |
| Sound | Marco Colosimo | ADR Recordist |
| Visual Effects | Francois Cote-Paquet | Visual Effects Supervisor |
| Visual Effects | Justine Paynat-Sautivet | Visual Effects Supervisor |
| Visual Effects | Pierre Buffin | Visual Effects Supervisor |
| Visual Effects | William Banti | Visual Effects Supervisor |
| Visual Effects | Laure Ferreira Lima | Visual Effects Production Assistant |
| Visual Effects | Camille Gibrat | Visual Effects Production Assistant |
| Visual Effects | Angie Alavez | I/O Manager |
| Visual Effects | Michael Kannard | Imaging Science |
| Production | Mark Bennett | Casting Director |
| Camera | Helen Cho Anthos | Camera Operator |
| Camera | Zachary Sieffert | Camera Operator |
| Camera | William Tanner Sampson | Steadicam Operator |
| Camera | Robert M. Barr | First Assistant "B" Camera |
| Camera | Melanie Gates | Second Assistant "A" Camera |
| Camera | Hunter Thomas | Second Assistant "B" Camera |
| Camera | Nick Ramey | Aerial Camera |
| Production | David Lawson Jr. | Producer |
| Visual Effects | Joachim Zell | Imaging Science |
| Directing | Aaron Moorhead | Director |
| Directing | Justin Benson | Director |
| Writing | Justin Benson | Writer |
| Camera | Aaron Moorhead | Director of Photography |
| Art | Ariel Vida | Production Design |
| Art | Kati Simon | Art Direction |
| Art | Abigail Sanford | Set Decoration |
| Costume & Make-Up | Laura Cristina Ortiz | Costume Design |
| Editing | Michael Felker | Editor |
| Editing | Justin Benson | Editor |
| Editing | Aaron Moorhead | Editor |
| Production | Natalie Perrotta | Executive Producer |
| Production | Nick Spicer | Executive Producer |
| Production | Aram Tertzakian | Executive Producer |
| Production | Nate Bolotin | Executive Producer |
| Production | Michael Mendelsohn | Producer |
| Production | Aaron Moorhead | Producer |
| Production | Justin Benson | Producer |
| Sound | Jimmy LaValle | Original Music Composer |
| Crew | Marisa Clayton | Post Production Supervisor |
| Production | John Craighead | Unit Production Manager |
