Janine en Sandy zijn een lesbisch stel dat besluit een kind te krijgen, maar na een paar jaar overlijdt Sandy. Deze tragedie wordt door Sandy's ouders uitgebuit om het meisje uit de zorg van Janine te ontrukken. Maar dan, en ondanks dat de wetten tegen haar gelden, besluit Janine te vechten om de voogdij over haar dochter terug te krijgen.
Nee, helaas is What Makes a Family nog niet beschikbaar op Netflix in Nederland.
| Production | Barbra Streisand | Executive Producer |
| Production | Cis Corman | Executive Producer |
| Production | Whoopi Goldberg | Executive Producer |
| Production | Robert L. Freedman | Co-Producer |
| Production | Neil Meron | Executive Producer |
| Production | Craig Zadan | Executive Producer |
| Production | Dave Mace | Co-Producer |
| Production | Wendy Grean | Producer |
| Production | Tom Leonardis | Co-Producer |
| Production | Stephanie Hagen | Associate Producer |
| Sound | David Mansfield | Music |
| Editing | Keith Reamer | Editor |
| Camera | Rhett Morita | Director of Photography |
| Production | Mary V. Buck | Casting |
| Production | John Buchan | Casting |
| Production | Susan Edelman | Casting |
| Art | Astra Burka | Art Direction |
| Art | Perri Gorrara | Production Design |
| Costume & Make-Up | Suzette Daigle | Costume Design |
| Art | Ane Christensen | Set Decoration |
| Costume & Make-Up | Julia L. Walker | Hairstylist |
| Costume & Make-Up | Pam Roberts | Key Hair Stylist |
| Costume & Make-Up | Mark DeLuca | Special Effects Makeup Artist |
| Costume & Make-Up | Marie Nardella | Makeup Department Head |
| Directing | Eric J. Robertson | Second Assistant Director |
| Directing | William Spahic | First Assistant Director |
| Sound | Kerri Wilson | Supervising Sound Editor |
| Camera | Sophie Giraud | Still Photographer |
| Directing | Maggie Greenwald | Director |
| Writing | Robert L. Freedman | Writer |
| Production | David Hood | Unit Production Manager |
| Art | Mark Harman | Property Master |
| Costume & Make-Up | Catherine Ashton | Assistant Costume Designer |
| Costume & Make-Up | Heather Blurton | Costume Supervisor |
| Camera | Paul Boucher | Camera Operator |
| Camera | Kim Derko | Camera Operator |
| Camera | Richard Wilmot | Steadicam Operator |
| Camera | Ted Overton | First Assistant Camera |
| Lighting | Bob McAdam | Gaffer |
| Camera | Peter Schalakowskyj | Key Grip |
| Sound | Stuart French | Production Sound Mixer |
| Production | Elspeth Cassar | Production Coordinator |
| Directing | Sheona McDonald | Script Supervisor |
| Directing | Robert Chalmers | Third Assistant Director |
| Directing | Sean Watson | Third Assistant Director |
| Production | Gabe Fallus | Location Manager |
| Crew | Frank Eldridge | Transportation Coordinator |
| Art | Fred Mendelson | Construction Coordinator |
| Production | Barbara Pecs | Production Accountant |
| Sound | Sherry Klein | Sound Re-Recording Mixer |
| Sound | Eric Behrend | Sound Re-Recording Mixer |
| Sound | Joel Fein | Sound Re-Recording Mixer |
| Editing | Anna Josenhans | Associate Editor |
| Sound | Allan K. Rosen | Music Editor |
