Zeke en William zijn rechercheurs die samen onderzoek doen naar een reeks gruwelijke misdaden. Ook Marcus, de vader van Zeke, wordt op de zaak gezet. De moordenaar blijkt het gemunt te hebben op de politie. Gaandeweg wordt duidelijk dat de zaak te maken heeft met Jigsaw en dat het werk van laatstgenoemde wordt voortgezet.
Nee, helaas is Spiral: From the Book of Saw nog niet beschikbaar op Netflix in Nederland.
| Editing | Dev Singh | Editor |
| Production | Stacey Testro | Executive Producer |
| Production | Jason Constantine | Executive Producer |
| Production | Gregg Hoffman | Executive Producer |
| Production | Kevin Greutert | Executive Producer |
| Costume & Make-Up | Patrick Baxter | Special Effects Makeup Artist |
| Costume & Make-Up | Randy Daudlin | Makeup Department Head |
| Costume & Make-Up | Keirsten Morris | Key Makeup Artist |
| Costume & Make-Up | Silvia Platsis | Makeup Artist |
| Production | Peter Block | Executive Producer |
| Production | Ketura Kestin | Co-Producer |
| Production | Stephanie Gorin | Casting |
| Sound | Steve Baine | Foley Artist |
| Sound | Tom Bjelic | Sound Editor |
| Sound | Emilie Boucek | Sound Editor |
| Sound | Keith Elliott | Sound Re-Recording Mixer |
| Sound | Mark Gingras | Supervising Sound Editor |
| Sound | Ormangoren Gurkan | Boom Operator |
| Sound | William Kellerman | Foley Artist |
| Sound | John Laing | Sound Editor |
| Sound | Daniel Moctezuma | Foley Recordist |
| Sound | Angelo Raguso | Sound Designer |
| Sound | Jeffrey Roy | ADR Mixer |
| Sound | Mark Wilkening | ADR Mixer |
| Sound | Robert Woolfson | Sound Mixer |
| Sound | Xerxes Shuzhang Yang | Sound Editor |
| Sound | Mark Zsifkovits | Sound Re-Recording Mixer |
| Visual Effects | Jon Campfens | Visual Effects Supervisor |
| Visual Effects | Peter Denomme | Visual Effects Producer |
| Visual Effects | Pablo José Fuertes | Visual Effects Supervisor |
| Visual Effects | Tobias Kreißl | Visual Effects Supervisor |
| Visual Effects | Tim Luecker | Visual Effects Producer |
| Visual Effects | Rafael Pacheco | Visual Effects Coordinator |
| Visual Effects | Beau Parsons | Visual Effects Supervisor |
| Lighting | Ira Cohen | Gaffer |
| Directing | Nadia Guglieri | Script Supervisor |
| Sound | Ahmar Bailey | Music Producer |
| Sound | Jordan Burg | Music Supervisor |
| Sound | Scott Greer | Music Supervisor |
| Sound | Simon Miminis | Music Editor |
| Art | Dhaval Jasani | Location Scout |
| Production | Paul Franklin | Location Manager |
| Visual Effects | Jeff Skochko | Special Effects Supervisor |
| Crew | Shawn Morris | Special Effects Technician |
| Crew | Hugh Goodden | Special Effects Technician |
| Art | Farris Popat | Set Dresser |
| Art | Marc R. Taylor | Set Dresser |
| Costume & Make-Up | François Dagenais | Special Effects Makeup Artist |
| Art | Ines Rose | Art Direction |
| Writing | Leigh Whannell | Characters |
| Writing | James Wan | Characters |
| Production | Marc Dassas | Production Manager |
| Directing | David Sparkes | First Assistant Director |
| Directing | Jonnie Katz | Second Assistant Director |
| Crew | Philip Stilman | Post Production Supervisor |
| Crew | Robert Racki | Stunt Coordinator |
| Crew | Branko Racki | Stunt Coordinator |
| Crew | Shelley Cook | Stunts |
| Crew | Mark Schneider | Stunts |
| Crew | Mike Gow | Stunts |
| Crew | Billy Oliver | Stunts |
| Crew | Eric Daniel | Stunt Double |
| Crew | Kiante Elam | Stunt Double |
| Crew | Joseph Racki | Stunt Double |
| Crew | Torianna Lee | Stunt Double |
| Crew | Dylan Rampulla | Stunt Double |
| Crew | Curtis Parker | Stunt Double |
| Crew | Billy Oliver | Stunt Driver |
| Crew | Mark Schneider | Stunt Driver |
| Crew | Scott Cook | Stunt Driver |
| Crew | Branko Racki | Stunts |
| Crew | Mike Chute | Stunts |
| Crew | Ermes Blarasin | Stunts |
| Crew | Cecil Philips | Stunts |
| Camera | Rion Gonzales | Camera Operator |
| Camera | Michael Fylyshtan | Steadicam Operator |
| Camera | Liam Ward | Steadicam Operator |
| Camera | Liam Ward | Camera Operator |
| Camera | Michael Fylyshtan | Camera Operator |
| Directing | Josh Keller | Third Assistant Director |
| Directing | Kristen Calibaba | Third Assistant Director |
| Sound | Andy Gershon | Music Supervisor |
| Art | Michael Nesbitt | Assistant Art Director |
| Art | David Lewington | Assistant Art Director |
| Art | David Lewington | Set Designer |
| Art | Olivia Edmonds | Art Department Coordinator |
| Costume & Make-Up | Alexander Narizni | On Set Dresser |
| Art | Stefano Amelio | Set Dresser |
| Art | Martin Budd | Set Dresser |
| Art | Kris Kearns | Set Dresser |
| Costume & Make-Up | Keirsten Morris | Makeup Artist |
| Costume & Make-Up | Kevin Barry | Assistant Costume Designer |
| Costume & Make-Up | Lisa Deveaux | Makeup Artist |
| Costume & Make-Up | Vann E. Gouweleeuw | Assistant Makeup Artist |
| Costume & Make-Up | Jennelle Greene | Assistant Makeup Artist |
| Costume & Make-Up | François Dagenais | Prosthetic Designer |
| Crew | Traci Loader | Makeup Effects |
| Crew | Patrick Baxter | Makeup Effects |
| Costume & Make-Up | Allison Mondesir | Hair Department Head |
| Costume & Make-Up | Paulina Harcus | Key Hair Stylist |
| Costume & Make-Up | Donna Hunt | Hairstylist |
| Costume & Make-Up | Marcos Smith | Hairstylist |
| Writing | Pete Goldfinger | Writer |
| Writing | Josh Stolberg | Writer |
| Directing | Darren Lynn Bousman | Director |
| Production | Mark Burg | Producer |
| Production | Oren Koules | Producer |
| Production | Daniel J. Heffner | Executive Producer |
| Production | Chris Rock | Executive Producer |
| Production | James Wan | Executive Producer |
| Production | Leigh Whannell | Executive Producer |
| Art | Anthony Cowley | Production Design |
| Art | Greg Chown | Art Direction |
| Art | Terri Drennan | Set Decoration |
| Costume & Make-Up | Laura Montgomery | Costume Design |
| Sound | Charlie Clouser | Original Music Composer |
| Camera | Jordan Oram | Director of Photography |
| Sound | 21 Savage | Songs |
