In de straten van New Orleans begint het nieuws te verspreiden over een mysterieuze nieuwe pil die superkrachten ontgrendelt die uniek zijn voor elke gebruiker. De vangst: u weet niet wat er zal gebeuren totdat u het neemt. Terwijl sommigen een kogelvrije huid, onzichtbaarheid en superkracht ontwikkelen, vertonen anderen een dodelijkere reactie. Maar wanneer de pil de criminaliteit in de stad tot gevaarlijke niveaus doet escaleren, werkt een lokale agent (Joseph Gordon-Levitt) samen met een tienerdealer (Dominique Fishback) en een voormalige soldaat die wordt gevoed door een geheime vendetta (Jamie Foxx) om de macht met macht en het risico nemen om de pil te nemen om de groep die verantwoordelijk is voor het maken ervan op te sporen en te stoppen.
| Crew | Janelle Beaudry | Stunts |
| Visual Effects | Jared Hasselbach | VFX Artist |
| Crew | Vanessa Motta | Stunt Double |
| Production | Tyler Hohmann | Assistant Location Manager |
| Crew | Taryn Terrell | Stunts |
| Visual Effects | Wakako Sekine | Compositing Artist |
| Visual Effects | Olivier Jobin | Visual Effects Coordinator |
| Directing | Ariel Schulman | Director |
| Production | Bryan Unkeless | Producer |
| Directing | Henry Joost | Director |
| Writing | Mattson Tomlin | Writer |
| Production | Eric Newman | Producer |
| Production | Orlee-Rose Strauss | Executive Producer |
| Camera | Michael Simmonds | Director of Photography |
| Production | Ray Angelic | Executive Producer |
| Production | John Papsidera | Casting |
| Sound | Joseph Trapanese | Original Music Composer |
| Art | Matthew Gatlin | Art Direction |
| Art | Jonathan Opgenhaffen | Art Direction |
| Editing | Jeff McEvoy | Editor |
| Art | John Sanchez | Art Direction |
| Art | Cynthia La Jeunesse | Set Decoration |
| Costume & Make-Up | Anthony Canonica | Special Effects Makeup Artist |
| Crew | Luca Borghese | Post Production Supervisor |
| Costume & Make-Up | Lindsay Gelfand | Prosthetic Makeup Artist |
| Costume & Make-Up | Ashley Levy | Makeup Department Head |
| Costume & Make-Up | Adam Walls | Key Makeup Artist |
| Production | Ian Watermeier | Unit Production Manager |
| Production | Michael B. Johnson | Production Supervisor |
| Costume & Make-Up | Crystal Jurado | Special Effects Key Makeup Artist |
| Costume & Make-Up | Göran Lundström | Prosthetic Makeup Artist |
| Costume & Make-Up | Sherri Hamilton | Key Hair Stylist |
| Costume & Make-Up | Dee Leveque | Hairstylist |
| Costume & Make-Up | Lana Mora | Makeup Artist |
| Costume & Make-Up | Daina Daigle | Hair Department Head |
| Costume & Make-Up | Stacey Perry | Makeup Artist |
| Costume & Make-Up | Sharen Davis | Costume Design |
| Costume & Make-Up | Michael Marino | Makeup Effects Designer |
| Costume & Make-Up | Ignacia Soto-Aguilar | Key Makeup Artist |
| Art | Naomi Shohan | Production Design |
| Art | Tom Frohling | Art Direction |
| Production | Michael Morgan | Post Production Producer |
| Costume & Make-Up | Stacy Kelly | Makeup Department Head |
| Costume & Make-Up | Sherri Hamilton | Hair Department Head |
| Crew | Minerva Adams | Stunt Double |
| Crew | Kenny Bartram | Stunt Double |
| Crew | Sadiqua Bynum | Stunt Double |
| Crew | Gui DaSilva-Greene | Stunt Double |
| Crew | Joe Nin Williams | Stunts |
| Crew | Cory DeMeyers | Stunt Coordinator |
| Crew | Liam Day | Stunt Double |
| Crew | Timothy Eulich | Stunt Double |
| Crew | Michael Endoso | Stunt Double |
| Art | Thomas du Crest | Concept Artist |
| Visual Effects | Lilia Collar | Digital Compositor |
