In de straten van New Orleans begint het nieuws te verspreiden over een mysterieuze nieuwe pil die superkrachten ontgrendelt die uniek zijn voor elke gebruiker. De vangst: u weet niet wat er zal gebeuren totdat u het neemt. Terwijl sommigen een kogelvrije huid, onzichtbaarheid en superkracht ontwikkelen, vertonen anderen een dodelijkere reactie. Maar wanneer de pil de criminaliteit in de stad tot gevaarlijke niveaus doet escaleren, werkt een lokale agent (Joseph Gordon-Levitt) samen met een tienerdealer (Dominique Fishback) en een voormalige soldaat die wordt gevoed door een geheime vendetta (Jamie Foxx) om de macht met macht en het risico nemen om de pil te nemen om de groep die verantwoordelijk is voor het maken ervan op te sporen en te stoppen.
| Crew | Janelle Beaudry | Stunts |
| Visual Effects | Jared Hasselbach | VFX Artist |
| Crew | Vanessa Motta | Stunt Double |
| Production | Tyler Hohmann | Assistant Location Manager |
| Crew | Taryn Terrell | Stunts |
| Visual Effects | Wakako Sekine | Compositing Artist |
| Visual Effects | Olivier Jobin | Visual Effects Coordinator |
| Production | Eric Newman | Producer |
| Writing | Mattson Tomlin | Writer |
| Directing | Henry Joost | Director |
| Directing | Ariel Schulman | Director |
| Production | Bryan Unkeless | Producer |
| Camera | Michael Simmonds | Director of Photography |
| Production | Ray Angelic | Executive Producer |
| Production | John Papsidera | Casting |
| Production | Orlee-Rose Strauss | Executive Producer |
| Art | John Sanchez | Art Direction |
| Art | Tom Frohling | Art Direction |
| Costume & Make-Up | Sherri Hamilton | Key Hair Stylist |
| Sound | Joseph Trapanese | Original Music Composer |
| Editing | Jeff McEvoy | Editor |
| Art | Jonathan Opgenhaffen | Art Direction |
| Art | Naomi Shohan | Production Design |
| Art | Cynthia La Jeunesse | Set Decoration |
| Production | Michael B. Johnson | Production Supervisor |
| Production | Ian Watermeier | Unit Production Manager |
| Costume & Make-Up | Daina Daigle | Hair Department Head |
| Crew | Luca Borghese | Post Production Supervisor |
| Costume & Make-Up | Göran Lundström | Prosthetic Makeup Artist |
| Costume & Make-Up | Crystal Jurado | Special Effects Key Makeup Artist |
| Costume & Make-Up | Stacy Kelly | Makeup Department Head |
| Costume & Make-Up | Sherri Hamilton | Hair Department Head |
| Costume & Make-Up | Lana Mora | Makeup Artist |
| Costume & Make-Up | Lindsay Gelfand | Prosthetic Makeup Artist |
| Costume & Make-Up | Mike Marino | Makeup Effects Designer |
| Costume & Make-Up | Ignacia Soto-Aguilar | Key Makeup Artist |
| Costume & Make-Up | Sharen Davis | Costume Design |
| Costume & Make-Up | Dee Leveque | Hairstylist |
| Costume & Make-Up | Ashley Levy | Makeup Department Head |
| Costume & Make-Up | Adam Walls | Key Makeup Artist |
| Production | Michael Morgan | Post Production Producer |
| Art | Matthew Gatlin | Art Direction |
| Costume & Make-Up | Anthony Canonica | Special Effects Makeup Artist |
| Costume & Make-Up | Stacey Perry | Makeup Artist |
| Crew | Michael Endoso | Stunt Double |
| Crew | Joe Nin Williams | Stunts |
| Crew | Timothy Eulich | Stunt Double |
| Crew | Liam Day | Stunt Double |
| Crew | Gui DaSilva-Greene | Stunt Double |
| Crew | Minerva Adams | Stunt Double |
| Crew | Kenny Bartram | Stunt Double |
| Crew | Cory DeMeyers | Stunt Coordinator |
| Crew | Sadiqua Bynum | Stunt Double |
| Art | Thomas du Crest | Concept Artist |
| Visual Effects | Lilia Collar | Digital Compositor |
| Art | Teddy Blanks | Main Title Designer |
| Visual Effects | Matthew Twyford | Visual Effects Supervisor |
