De 22-jarige drugsdealer Chris (Emile Hirsch) schakelt huurmoordenaar Joe Cooper (Ma hew McConaughey) in om zijn moeder uit de weg te ruimen. Met de uitkering van haar levensverzekering kan Chris zijn schulden afbetalen. De slechtgemanierde huurmoordenaar wil de klus wel klaren, op voorwaarde dat Chris' zusje Dottie (Juno Temple) als seksueel onderpand dient totdat hij betaald krijgt. Met tegenzin besluit Chris zijn schuld boven het welzijn van zijn zus te stellen en stemt in met het aanbod. Maar wat als hij het geld nooit bij elkaar krijgt
Nee, helaas is Killer Joe nog niet beschikbaar op Netflix in Nederland.
| Directing | William Friedkin | Director |
| Writing | Tracy Letts | Screenplay |
| Production | Denise Chamian | Casting |
| Costume & Make-Up | Peggy Schnitzer | Costume Design |
| Camera | Caleb Deschanel | Director of Photography |
| Production | Christopher Woodrow | Executive Producer |
| Production | Nicolas Chartier | Producer |
| Production | Scott Einbinder | Producer |
| Crew | Danny Epper | Stunts |
| Production | Vicki Cherkas | Executive Producer |
| Production | Ryan Westheimer | Line Producer |
| Production | Zev Foreman | Executive Producer |
| Production | Patrick Newall | Co-Producer |
| Production | Patrick Newall | Unit Production Manager |
| Production | Laurence Freed | Co-Executive Producer |
| Production | Molly Conners | Executive Producer |
| Production | Jamin O'Brien | Co-Executive Producer |
| Production | Eli Selden | Associate Producer |
| Editing | Darrin Navarro | Editor |
| Art | Franco-Giacomo Carbone | Production Design |
| Art | Alice Baker | Set Decoration |
| Production | Jenn Lee | Production Supervisor |
| Sound | Steve Boeddeker | Sound Designer |
| Crew | Mark T. Henderson | Propmaker |
| Art | Patcharee Blanchard | Set Dresser |
| Art | Charles Bodenheimer | Painter |
| Art | Jeffrey Pratt Gordon | Assistant Property Master |
| Art | Lindanne Lewis | Painter |
| Art | April LaBranche | Art Department Coordinator |
| Crew | James J. Hershey | Propmaker |
| Art | Jason Portera | Set Dresser |
| Art | Vanessa Merrill | Graphic Designer |
| Art | Ember Soberman | Painter |
| Art | Marcus Turchi | Construction Coordinator |
| Art | Spencer J. Abadie | Construction Buyer |
| Art | David Lee Toth | Set Dresser |
| Art | Brook Yeaton | Property Master |
| Art | Paul Blanchard | Leadman |
| Costume & Make-Up | Cory Parker | On Set Dresser |
| Crew | Jeff Garbacz | Propmaker |
| Art | Sian C. Sanzone | Painter |
| Art | Wendy Guerrera | Painter |
| Art | Nicole LaBranche | Art Department Coordinator |
| Crew | Rick Broderman | Scenic Artist |
| Sound | Tyler Bates | Original Music Composer |
| Crew | O.J. Knighten | Animal Wrangler |
| Directing | Chuck Picerni Jr. | Second Unit Director |
| Costume & Make-Up | Donna Spahn | Assistant Hairstylist |
| Directing | Michael Salven | First Assistant Director |
| Directing | George Bott | Second Assistant Director |
| Costume & Make-Up | Marcos Gonzales | Key Hair Stylist |
| Costume & Make-Up | Krystal Kershaw | Makeup Department Head |
| Costume & Make-Up | Adrienne Lynn | Assistant Makeup Artist |
| Production | Giancarlo J. Sini | Production Manager |
| Crew | Chuck Picerni Jr. | Stunt Coordinator |
| Costume & Make-Up | Allison Bauserman | Set Costumer |
| Costume & Make-Up | Kent Richard | Assistant Hairstylist |
| Production | Lauren Claret | Consulting Accountant |
