Diverse stelletjes worstelen met hun problemen en hun verhalen raken in elkaar verstrengeld. Antonio, een voormalige Napolitaanse apotheker en nu lid van het Europees Parlement, begint een relatie met Olga, die hij ontmoette in een hotel in München. Max, een verstrooide Romeinse architect, ligt in scheiding. Dan wordt hij verliefd op Sandra, niet wetende dat dit de advocaat is van zijn vrouw. Marco, net getrouwd met Floriana, komt na jaren Consuelo, een oude liefde, weer tegen en doet alsof hij niet getrouwd is. Fabio is suïcidaal nadat zijn vriendin het uitmaakte door middel van een sms. Bij de praktijk van zijn psychiater ontmoet hij Valentina.
Nee, helaas is Ex - Amici come prima! nog niet beschikbaar op Netflix in Nederland.
| Directing | Carlo Vanzina | Director |
| Sound | Giuliano Taviani | Original Music Composer |
| Sound | Carmelo Travia | Original Music Composer |
| Crew | Federico Cioccolanti | Post Production Supervisor |
| Writing | Enrico Vanzina | Screenplay |
| Production | Clara Mancini | Administration |
| Costume & Make-Up | Nicoletta Ercole | Costume Design |
| Production | Edoardo Moracci | Unit Manager |
| Production | Andrea Zampetti | Production Accountant |
| Camera | Sascia Ippoliti | Steadicam Operator |
| Camera | Daniela Chioffi | Second Assistant Camera |
| Editing | Raimondo Crociani | Editor |
| Directing | Giorgio Melidoni | First Assistant Director |
| Production | Salvatore Morello | Executive Producer |
| Writing | Carlo Vanzina | Story |
| Costume & Make-Up | Biasi Pierangela | Makeup Artist |
| Sound | Marco Grillo | Sound |
| Directing | Paola Mengoni | Script Supervisor |
| Camera | Roberto Luzzi | Camera Operator |
| Camera | Duccio Maccari | First Assistant Camera |
| Camera | Giacomo Zampieri | Second Assistant Camera |
| Sound | Claudio Paolucci | Boom Operator |
| Production | Federico Santangelo | Location Manager |
| Directing | Matteo Vicario | Second Assistant Director |
| Art | Gaia Zambelli | Assistant Production Design |
| Writing | Enrico Vanzina | Story |
| Art | Daniela Zorzetto | Set Decoration |
| Production | Simona Vescovi | Line Producer |
| Production | Sabrina Serangeli | Production Coordinator |
| Production | Rita Tamantini | Unit Manager |
| Costume & Make-Up | Gino Tamagnini | Makeup Department Head |
| Production | Giulio Steve | Delegated Producer |
| Production | Maria Raffaella Faggiano | Location Manager |
| Art | Anca Rafan | Assistant Production Design |
| Writing | Carlo Vanzina | Screenplay |
| Production | Federica Lucisano | Producer |
| Camera | Carlo Tafani | Director of Photography |
| Production | Barbara Giordani | Casting |
| Production | Alessandro Pantano | Production Secretary |
| Production | Aldo Piccapane | Production Secretary |
| Camera | Maria Marin | Still Photographer |
| Production | Fulvio Lucisano | Producer |
| Art | Tonino Zera | Production Design |
| Costume & Make-Up | Giammarco Gaeta | Hairstylist |
| Visual Effects | Stefano Marinoni | VFX Supervisor |
| Sound | Alessandro Giacco | Foley Artist |
| Editing | Shara Spinella | Assistant Editor |
| Editing | Marina Verri | Assistant Editor |
| Sound | Andrea Lancia | Sound Mixer |
| Sound | Dave Tinsley | Sound Editor |
| Visual Effects | Paola Trisoglio | Visual Effects Producer |
| Camera | Gianpaolo Majorana | Key Grip |
| Sound | Thomas Giorgi | Sound Effects Editor |
| Costume & Make-Up | Adel Saada | Hair Department Head |
| Lighting | Massimo Cecchini | Gaffer |