De inwoners van een mijnwerkersdorp ontdekken dat een chemisch ongelukje er voor gezorgd heeft dat honderden kleine spinnen gemuteerd zijn tot hongerige monsters van meters groot. Het is aan mijnwerker Chris McCormack en sheriff Sam Parker om een groep mensen bij elkaar te zoeken om de de bloeddorstige beesten te bestrijden. Onder hen zijn de kinderen van de sheriff (Mike en Ashley) en de paranoïde radiomaker Harlan.
Nee, helaas is Eight Legged Freaks nog niet beschikbaar op Netflix in Nederland.
| Writing | Ellory Elkayem | Screenplay |
| Production | Peter Winther | Executive Producer |
| Sound | John Ottman | Original Music Composer |
| Production | William Fay | Executive Producer |
| Camera | John S. Bartley | Director of Photography |
| Production | Dean Devlin | Producer |
| Production | Bruce Berman | Producer |
| Directing | Ellory Elkayem | Director |
| Writing | Jesse Alexander | Screenplay |
| Production | Roland Emmerich | Executive Producer |
| Production | April Webster | Casting |
| Production | Paula Rosenberg | Casting |
| Crew | Pat Banta | Stunts |
| Crew | Jim Holley | Stunt Driver |
| Crew | Heather Callow | Stunts |
| Crew | Louie Franco | Stunt Driver |
| Crew | James M. Churchman | Stunts |
| Crew | John Hateley | Stunts |
| Art | Matthew Bekoff | Set Designer |
| Crew | Rick Miller | Stunt Driver |
| Crew | 'Mad' Mike Jones | Stunt Driver |
| Editing | David Siegel | Editor |
| Sound | Jim Fitzpatrick | Sound Re-Recording Mixer |
| Camera | Gary L. Camp | Steadicam Operator |
| Directing | Robin Anderson | Script Supervisor |
| Art | Terry Kempf | Construction Coordinator |
| Production | Alan Benoit | Location Manager |
| Art | Chas. Butcher | Art Direction |
| Camera | Jon Baronn Farmer | Still Photographer |
| Crew | Terry J. Erdmann | Unit Publicist |
| Visual Effects | Karen E. Goulekas | Visual Effects Supervisor |
| Costume & Make-Up | Alix Friedberg | Costume Design |
| Crew | Yves De Bono | Special Effects Coordinator |
| Crew | Kosta Saric | Visual Effects Editor |
| Sound | Dan Hegeman | Sound Effects Editor |
| Camera | Anna Foerster | Additional Photography |
| Costume & Make-Up | Rick Sharp | Makeup Department Head |
| Sound | Kerry Ann Carmean | Sound Effects Editor |
| Sound | Dino DiMuro | Sound Effects Editor |
| Visual Effects | Kelvin Lee | Animation Supervisor |
| Visual Effects | Thomas Dadras | Visual Effects Supervisor |
| Sound | Gary Gegan | Sound Re-Recording Mixer |
| Crew | Jo Ann Smith | Studio Teachers |
| Sound | Christopher Assells | Sound Effects Editor |
| Visual Effects | Drew McKeen | Visual Effects Producer |
| Sound | Amanda Goodpaster | Music Editor |
| Costume & Make-Up | Kim Collea | Makeup Artist |
| Art | Catherine A. McCabe | Art Department Coordinator |
| Sound | James Moriana | Foley |
| Editing | Michel Aller | First Assistant Editor |
| Crew | Charlie Brewer | Stunt Coordinator |
| Costume & Make-Up | Deborah Hall | Costume Supervisor |
| Art | Marcia Calosio | Set Decoration |
| Art | Beverli Eagan | Set Designer |
| Sound | Gary Mundheim | Sound Effects Editor |
| Sound | Scott Wolf | Supervising Sound Editor |
| Visual Effects | Joachim Grüninger | Visual Effects Supervisor |
| Camera | Curt Pair | Camera Operator |
| Art | Richard Lambert | Leadman |
| Costume & Make-Up | Gina G. Aller | Set Costumer |
| Production | Kelly Van Horn | Co-Producer |
| Crew | Mike McNally | Set Medic |
| Costume & Make-Up | Claudia Breckenridge | Hairstylist |
| Crew | James K. Jensen | Post Production Supervisor |
| Crew | Gregg Singer | Picture Car Coordinator |
| Crew | George Bolton | Driver |
| Crew | John W. Ervin | Set Production Assistant |
| Costume & Make-Up | Scott W. Farley | Key Hair Stylist |
| Crew | Neil Gahm | Propmaker |
| Crew | Rich Ragsdale | Additional Music |
| Art | Kristen Spinning | Standby Painter |
| Crew | Steve Roll | Carpenter |
| Camera | David E. Baron | First Assistant Camera |
| Visual Effects | Tim T. Cunningham | Visual Effects Coordinator |
| Writing | Randy Kornfield | Story |
| Crew | Marie Randall | Craft Service |
| Crew | James Marbas | Digital Effects Supervisor |
| Crew | Leo Corey Castellano | Makeup Effects |
| Writing | Ellory Elkayem | Story |
| Sound | Larry Groupé | Orchestrator |
| Production | Scott Baldyga | Casting Associate |
| Sound | Casey Stone | Scoring Mixer |
| Sound | Kate Jesse | Boom Operator |
| Visual Effects | Andy Barrios | Digital Compositors |
| Sound | Peter Geoco | Production Sound Mixer |
| Sound | Peter Afterman | Music Supervisor |
| Sound | Jeff Glueck | Sound Engineer |
| Crew | John Alden | Stunts |
| Crew | Michael B. Russell | Transportation Captain |
| Sound | Daniel S. Irwin | Sound Editor |
| Visual Effects | Jens Döldissen | Special Effects Supervisor |
| Production | Daryl C. Lefever | Production Accountant |
| Production | Karen O'Toole | Production Coordinator |
| Art | Charles William Breen | Production Design |
| Production | Kelly Van Horn | Unit Production Manager |
| Crew | Alex Madison | Stunts |
| Art | John A. Stewart Jr. | Assistant Property Master |
| Costume & Make-Up | Maggie McFarland | Key Set Costumer |
| Lighting | John Stewart | Underwater Gaffer |
| Directing | Lars P. Winther | First Assistant Director |
| Production | Cindy Franke | Assistant Production Coordinator |
| Editing | Mo Henry | Negative Cutter |
| Art | Vicki Dittemore | Set Dresser |
| Crew | Lewis Arquette | In Memory Of |
| Camera | Tim Ryan | Key Grip |
| Crew | Cris Rankin | Animal Wrangler |
| Visual Effects | Carol Ashley | 3D Artist |
| Sound | Damon Intrabartolo | Conductor |
| Directing | Paul Bernard | Second Assistant Director |
| Sound | George Doering | Musician |
| Visual Effects | Andrew Tamandl | VFX Artist |
| Editing | David Orr | Color Timer |
| Art | Keith Mosca | Property Master |
| Crew | Andy Gill | Stunts |
| Camera | Michael Green | "A" Camera Operator |
| Camera | Gary L. Camp | "B" Camera Operator |
| Camera | Roy Heath | Grip |
| Crew | Ron Colucci | Special Effects |
| Crew | Ron Colucci | Special Effects Technician |
| Visual Effects | Xye | Visual Effects |
| Costume & Make-Up | Tina Sims | Assistant Hairstylist |
| Visual Effects | Abra Grupp | Compositing Supervisor |
| Sound | Dirk Stout | Utility Sound |
| Production | Karen Turner | Payroll Accountant |
| Lighting | Scott Herrick | Rigging Gaffer |
| Crew | Kim Hyde | Set Medic |
| Camera | Jay Coolidge | First Assistant "B" Camera |
| Lighting | Kenny Christiansen | Best Boy Electric |
| Production | Shelly Boucher | Production Assistant |
| Production | Christian Feldhaus | First Assistant Accountant |
| Visual Effects | John Bozzalla | Visual Effects Production Assistant |
| Production | Shari Lee | Production Secretary |
| Art | Mark Hurtado | Storyboard Artist |
| Sound | Jessica Clements | Music Coordinator |
| Sound | Brian Basham | ADR Recordist |
| Costume & Make-Up | Blanca Garcia | Costumer |
| Editing | Ryan Chan | Assistant Editor |
| Sound | Michael J. Broomberg | Foley Artist |
| Production | Cindi Reiss | Extras Casting |
| Sound | Ron Bedrosian | ADR Mixer |
| Crew | Ken Gorrell | Special Effects Technician |
| Visual Effects | Greg Groenekamp | Visual Effects Compositor |
| Camera | Jason Casillas | Assistant Camera |
| Camera | Matt Balzarini | Second Assistant Camera |
