Julianne (Julia Roberts) en Michael hebben de afspraak dat, als ze beiden nog vrijgezel zijn vóór hun 28ste verjaardag, zij met elkaar zullen trouwen. Maar vier dagen voor de kritieke ‘deadline’ belt Michael Julianne op met de heugelijke mededeling dat hij de ware heeft gevonden. Jullianne is vast van plan om Michael's voorgenomen huwelijk met de vrouw van zijn dromen, de piepjonge Kimmy (Cameron Diaz), te saboteren en ze gaat hen opzoeken. Helaas blijkt de ‘aanstaande’ van Michael een schat van een meid te zijn. Maar, schattig of niet, voor Julianne dringt de tijd. Over drie dagen is de bruiloft en die zal, wat haar betreft, zeker geen doorgang vinden!
Nee, helaas is My Best Friend's Wedding nog niet beschikbaar op Netflix in Nederland.
| Writing | Ronald Bass | Screenplay |
| Production | Ronald Bass | Producer |
| Production | Jerry Zucker | Producer |
| Production | Gil Netter | Executive Producer |
| Production | Patricia Whitcher | Executive Producer |
| Sound | James Newton Howard | Original Music Composer |
| Camera | László Kovács | Director of Photography |
| Editing | Garth Craven | Editor |
| Editing | Lisa Fruchtman | Editor |
| Directing | P.J. Hogan | Director |
| Crew | Linda Perlin | Stunts |
| Crew | Stacy Logan | Stunts |
| Crew | Rick LeFevour | Stunt Coordinator |
| Production | David Rubin | Casting |
| Art | Richard Sylbert | Production Design |
| Art | Karen Fletcher Trujillo | Art Direction |
| Costume & Make-Up | Jeffrey Kurland | Costume Design |
| Production | Bill Johnson | Associate Producer |
| Art | William Kemper Wright | Set Decoration |
| Costume & Make-Up | Deborah K. Dee | Key Hair Stylist |
| Costume & Make-Up | Richard Dean | Makeup Designer |
| Costume & Make-Up | Linda Melazzo | Key Makeup Artist |
| Costume & Make-Up | Karen Lynn Accattato | Makeup Artist |
| Costume & Make-Up | Lyndell Quiyou | Hair Designer |
| Costume & Make-Up | Anne Morgan | Hair Department Head |
| Costume & Make-Up | Noriko Watanabe | Makeup Department Head |
| Directing | Eric Heffron | First Assistant Director |
| Production | Patricia Whitcher | Unit Production Manager |
| Directing | Richard Oswald | Second Assistant Director |
| Directing | Richard S. Lederer | Second Second Assistant Director |
| Sound | John Morris | Supervising Sound Editor |
| Crew | Tom Ryba | Special Effects Coordinator |
| Crew | Eddie J. Fernandez | Stunts |
| Crew | James Fierro | Stunts |
| Crew | Carl Paoli | Stunt Double |
| Crew | Daniel Maldonado | Stunts |
| Crew | Kay Whipple | Stunts |
| Crew | Brian Christensen | Stunts |
| Crew | Mark Harper | Stunts |
| Camera | George Kohut | "A" Camera Operator |
| Camera | Gerrit Dangremond | "B" Camera Operator |
| Lighting | Richmond L. Aguilar | Chief Lighting Technician |
| Camera | Suzanne Tenner | Still Photographer |
| Sound | Bonnie Greenberg | Music Supervisor |
| Directing | Dru Anne Carlson | Script Supervisor |
| Art | Wenden K. Baldwin | Title Designer |
| Crew | Toni Basil | Choreographer |
| Crew | Tom Lowell | Stunts |
| Costume & Make-Up | John Glaser | Assistant Costume Designer |
