Julianne (Julia Roberts) en Michael hebben de afspraak dat, als ze beiden nog vrijgezel zijn vóór hun 28ste verjaardag, zij met elkaar zullen trouwen. Maar vier dagen voor de kritieke ‘deadline’ belt Michael Julianne op met de heugelijke mededeling dat hij de ware heeft gevonden. Jullianne is vast van plan om Michael's voorgenomen huwelijk met de vrouw van zijn dromen, de piepjonge Kimmy (Cameron Diaz), te saboteren en ze gaat hen opzoeken. Helaas blijkt de ‘aanstaande’ van Michael een schat van een meid te zijn. Maar, schattig of niet, voor Julianne dringt de tijd. Over drie dagen is de bruiloft en die zal, wat haar betreft, zeker geen doorgang vinden!
Nee, helaas is My Best Friend's Wedding nog niet beschikbaar op Netflix in Nederland.
| Production | Jerry Zucker | Producer |
| Editing | Lisa Fruchtman | Editor |
| Directing | P.J. Hogan | Director |
| Production | Gil Netter | Executive Producer |
| Writing | Ronald Bass | Screenplay |
| Sound | James Newton Howard | Original Music Composer |
| Camera | László Kovács | Director of Photography |
| Production | Ronald Bass | Producer |
| Production | Patricia Whitcher | Executive Producer |
| Editing | Garth Craven | Editor |
| Crew | Stacy Logan | Stunts |
| Crew | Rick LeFevour | Stunt Coordinator |
| Crew | Linda Perlin | Stunts |
| Production | David Rubin | Casting |
| Costume & Make-Up | Jeffrey Kurland | Costume Design |
| Art | Richard Sylbert | Production Design |
| Art | Karen Fletcher Trujillo | Art Direction |
| Production | Bill Johnson | Associate Producer |
| Crew | James Fierro | Stunts |
| Camera | Suzanne Tenner | Still Photographer |
| Directing | Richard S. Lederer | Second Second Assistant Director |
| Camera | Gerrit Dangremond | "B" Camera Operator |
| Art | William Kemper Wright | Set Decoration |
| Costume & Make-Up | Anne Morgan | Hair Department Head |
| Production | Patricia Whitcher | Unit Production Manager |
| Directing | Richard Oswald | Second Assistant Director |
| Crew | Kay Whipple | Stunts |
| Crew | Eddie J. Fernandez | Stunts |
| Crew | Brian Christensen | Stunts |
| Camera | George Kohut | "A" Camera Operator |
| Costume & Make-Up | Deborah K. Dee | Key Hair Stylist |
| Costume & Make-Up | Linda Melazzo | Key Makeup Artist |
| Lighting | Richmond L. Aguilar | Chief Lighting Technician |
| Crew | Carl Paoli | Stunt Double |
| Costume & Make-Up | Richard Dean | Makeup Designer |
| Costume & Make-Up | Noriko Watanabe | Makeup Department Head |
| Sound | John Morris | Supervising Sound Editor |
| Crew | Tom Ryba | Special Effects Coordinator |
| Crew | Daniel Maldonado | Stunts |
| Crew | Mark Harper | Stunts |
| Sound | Bonnie Greenberg | Music Supervisor |
| Costume & Make-Up | Karen Lynn Accattato | Makeup Artist |
| Crew | Toni Basil | Choreographer |
| Costume & Make-Up | Lyndell Quiyou | Hair Designer |
| Directing | Eric Heffron | First Assistant Director |
| Directing | Dru Anne Carlson | Script Supervisor |
| Art | Wenden K. Baldwin | Title Designer |
| Crew | Tom Lowell | Stunts |
| Costume & Make-Up | John Glaser | Assistant Costume Designer |
