Dr. Sherman Klump is een vriendelijke, briljante genetica professor die nogal last heeft van overgewicht. Wanneer de mooie Carla Purty op de universiteit les komt geven, wordt Sherman prompt straalverliefd en zoekt wanhopig naar middelen om zijn 200-kilo zware lichaam terug te brengen naar algemeen geaccepteerde normen en zo haar hart te winnen. Hij neemt een slok van zijn experimentele vetverminderende serum en verandert in Buddy Love, een gladde afgetrainde Don Juan.
Nee, helaas is The Nutty Professor nog niet beschikbaar op Netflix in Nederland.
| Directing | Tom Shadyac | Director |
| Camera | Julio Macat | Director of Photography |
| Editing | Don Zimmerman | Editor |
| Writing | David Sheffield | Screenplay |
| Writing | Barry W. Blaustein | Screenplay |
| Writing | Steve Oedekerk | Screenplay |
| Writing | Tom Shadyac | Screenplay |
| Production | Karen Kehela Sherwood | Executive Producer |
| Production | Jerry Lewis | Executive Producer |
| Production | Mark Lipsky | Executive Producer |
| Production | Tina Fortenberry | Production Supervisor |
| Visual Effects | Robert Stadd | Visual Effects Producer |
| Crew | Mickey Gilbert | Stunt Coordinator |
| Crew | Eugene Collier | Stunts |
| Crew | Tim Gilbert | Stunts |
| Crew | Stanton Barrett | Stunts |
| Crew | Jimmy Lewis Jr. | Stunts |
| Crew | Troy Gilbert | Stunts |
| Crew | Lance Gilbert | Stunts |
| Crew | Joe Finnegan | Stunts |
| Crew | Carlton Holder | Stunts |
| Crew | Bennie Moore | Stunts |
| Crew | Peter Horak | Stunts |
| Crew | Eddie Smith | Stunts |
| Crew | Chuck 'Chaz' Hosack | Stunts |
| Crew | Anthony G. Schmidt | Stunts |
| Crew | Jack Carpenter | Stunts |
| Art | Sally Thornton | Assistant Art Director |
| Crew | Marian Green | Stunts |
| Camera | David E. Diano | "B" Camera Operator |
| Camera | Billy Clevenger | First Assistant "B" Camera |
| Camera | Bruce McBroom | Still Photographer |
| Crew | Paul Murphey | Video Assist Operator |
| Sound | José Antonio García | Sound Mixer |
| Sound | Jonathan Fuh | Boom Operator |
| Crew | Jeff Erdmann | Cableman |
| Directing | Kathryn Weygand | Script Supervisor |
| Production | Gretchen van Zeebroeck | Production Coordinator |
| Production | Maureen Stanton-Leveque | Assistant Production Coordinator |
| Crew | Deborah Simmrin | Unit Publicist |
| Production | Bob Hartman | Payroll Accountant |
| Production | Glen Richard | First Assistant Accountant |
| Production | Laurie Dodsworth | Second Assistant Accountant |
| Lighting | Mike Moyer | Chief Lighting Technician |
| Lighting | Don Nygren | Chief Lighting Technician |
| Lighting | Richard Hartley | Assistant Chief Lighting Technician |
| Lighting | David Burnett | Assistant Chief Lighting Technician |
| Lighting | Ronald Kline | Rigging Gaffer |
| Camera | Gary Dagg | Key Grip |
| Camera | Mike Connors | Dolly Grip |
| Art | James F. Claytor Sr. | Set Designer |
| Art | Yvonne Garnier-Hackl | Set Designer |
| Art | Dawn Snyder | Set Designer |
| Art | Marisol Jiménez | Art Department Coordinator |
| Art | John Maskovich | Leadman |
| Art | Rick Young | Property Master |
| Production | Arlene Kehela | Location Manager |
| Art | Dennis DeWaay | Construction Coordinator |
| Art | Bruce J. Gfeller | Construction Coordinator |
| Crew | Lou Sumien Jr. | Projection |
| Editing | Don Thompson | First Assistant Editor |
| Sound | Steve Maslow | Sound Re-Recording Mixer |
| Sound | Gregg Landaker | Sound Re-Recording Mixer |
| Sound | Michael Hilkene | Supervising Sound Editor |
| Sound | Ed Callahan | Dialogue Editor |
| Sound | Simon Coke | Dialogue Editor |
| Sound | Jeff Rosen | Dialogue Editor |
| Sound | Michael Hilkene | ADR Supervisor |
| Sound | John O. Wilde | Foley Supervisor |
| Sound | Leslie Gaulin | Foley Editor |
| Sound | John T. Cucci | Foley Artist |
| Sound | Dan O'Connell | Foley Artist |
| Sound | James Ashwill | Foley Mixer |
| Production | Barbara Harris | ADR Voice Casting |
| Sound | Jeff Carson | Music Editor |
| Sound | J.J. George | Music Editor |
| Editing | Sandy Brundage | Negative Cutter |
| Editing | Jim Passon | Color Timer |
| Crew | Lane Leavitt | Stunts |
| Editing | Dean Zimmerman | Assistant Editor |
| Camera | David A. Armstrong | First Assistant "C" Camera |
| Crew | Francine Morris | Stunts |
| Writing | Jerry Lewis | Original Film Writer |
| Writing | Bill Richmond | Original Film Writer |
| Production | Eddie Murphy | Executive Producer |
| Production | Brian Grazer | Producer |
| Production | Russell Simmons | Producer |
| Production | James D. Brubaker | Co-Producer |
| Sound | David Newman | Original Music Composer |
| Production | Aleta Chappelle | Casting Director |
| Costume & Make-Up | Ha Nguyen | Costume Design |
| Costume & Make-Up | Rick Baker | Makeup Effects Designer |
| Art | William A. Elliott | Production Design |
| Art | Greg Papalia | Art Direction |
| Art | Kathryn Peters | Set Decoration |
| Costume & Make-Up | Beth Miller | Key Hair Stylist |
| Costume & Make-Up | Geri B. Oppenheim | Key Makeup Artist |
| Production | Daryl Kass | Unit Production Manager |
| Directing | David B. Householter | First Assistant Director |
| Directing | Daniel M. Stillman | Second Assistant Director |
| Directing | Rebecca Strickland | Second Assistant Director |
