Derek Zoolander, een succesvol mannelijk model, komt er op een dag achter dat zijn beste dagen in het vak achter zich liggen. Al een aantal jaren is hij uitgeroepen tot Male Model of the Year, maar dan gaat de felbegeerde titel opeens naar nieuwkomer Hansel. Dan wordt Derek benaderd door een zekere Mugatu die hem perspectieven biedt voor een nieuwe loopbaan.
| Directing | Ben Stiller | Director |
| Production | Scott Rudin | Producer |
| Production | Lauren Zalaznick | Executive Producer |
| Writing | Ben Stiller | Screenplay |
| Production | Adam Schroeder | Executive Producer |
| Editing | Greg Hayden | Editor |
| Writing | Drake Sather | Characters |
| Writing | Drake Sather | Screenplay |
| Writing | John Hamburg | Screenplay |
| Camera | Barry Peterson | Director of Photography |
| Sound | David Arnold | Original Music Composer |
| Writing | Ben Stiller | Characters |
| Production | Stuart Cornfeld | Producer |
| Production | Joel Gallen | Executive Producer |
| Production | Ben Stiller | Producer |
| Art | Peter C. Clarke | Property Master |
| Sound | Frank Smathers | Dialogue Editor |
| Production | Monica Levinson | Associate Producer |
| Production | Kathleen Chopin | Casting |
| Production | Juel Bestrop | Casting |
| Production | Jeanne McCarthy | Casting |
| Production | Celia D. Costas | Co-Producer |
| Sound | Randall Poster | Music Supervisor |
| Art | Robin Standefer | Production Design |
| Costume & Make-Up | David C. Robinson | Costume Design |
| Sound | George Drakoulias | Music Supervisor |
| Production | Dennis Widmyer | Art Department Production Assistant |
| Camera | François Duhamel | Still Photographer |
| Costume & Make-Up | Joanna Brett | Costume Supervisor |
| Lighting | Robert Anderson | Rigging Grip |
| Production | Maggie Kusik | Production Accountant |
| Sound | Nicholas Dodd | Orchestrator |
| Sound | Danny Michael | Production Sound Mixer |
| Visual Effects | David D. Johnson | Visual Effects Supervisor |
| Art | Melody Bishop | Art Department Coordinator |
| Camera | Dan Kneece | Steadicam Operator |
| Crew | LeJon Stewart | Stand In |
| Visual Effects | Don Lee | Digital Compositors |
| Art | Fred Merusi | Construction Coordinator |
| Costume & Make-Up | Catherine Childers | Hairstylist |
| Costume & Make-Up | Kate Biscoe | Makeup Artist |
| Costume & Make-Up | Jessica Marshall | Wigmaker |
| Production | Celia D. Costas | Unit Production Manager |
| Crew | Eric Myers | Unit Publicist |
| Directing | Eva Z. Cabrera | Script Supervisor |
| Lighting | Kelly Connors | Electrician |
| Crew | Fortunato Frattasio | Sequence Supervisor |
| Art | Donna Hamilton | Set Decoration |
| Crew | Jim Dolson | Scenic Artist |
| Sound | Dan Blazi | First Assistant Sound Editor |
| Sound | Christopher Emerson | Sound Effects Editor |
| Costume & Make-Up | Wayne Brackett | Set Dressing Artist |
| Crew | Joey McKneely | Choreographer |
| Crew | Joel Holland | Video Assist Operator |
| Camera | Patrick Capone | Camera Operator |
| Camera | David Norris | Helicopter Camera |
| Crew | Guy Merrick | Transportation Co-Captain |
| Editing | Dennis McNeill | Color Timer |
| Art | Kyung W. Chang | Assistant Art Director |
| Art | Guy Efrat | Location Scout |
| Art | Aric Lasher | Set Designer |
| Crew | Michael Merrick | Transportation Coordinator |
| Production | Blythe Cappello | Casting Associate |
| Sound | Thom 'Coach' Ehle | Dolby Consultant |
| Crew | Randy Kerber | Additional Music |
| Sound | David Kirschner | Sound Mixer |
| Visual Effects | Walter Garcia | Visual Effects Coordinator |
| Art | Richard Boris | Greensman |
| Crew | Scott Gertsen | Carpenter |
| Crew | Kendra Levenberg | Craft Service |
| Sound | Yann Delpuech | Sound Editor |
| Camera | Gerard Sava | Additional Camera |
| Camera | Sam DiMaggio | First Assistant Camera |
| Costume & Make-Up | Alan D'Angerio | Hair Designer |
| Crew | Maureen Beitler | Set Medic |
| Crew | Clayton J. Barber | Stunts |
| Crew | Mitch Goldstrom | Systems Administrators & Support |
| Sound | Perry Dodgson | Boom Operator |
| Costume & Make-Up | Joseph La Corte | Set Costumer |
| Crew | John C. Hartigan | Special Effects Coordinator |
| Sound | Robert Grieve | Supervising Sound Editor |
| Camera | Clyde W. Smith | Additional Photography |
| Costume & Make-Up | Naomi Donne | Makeup Designer |
| Crew | Brad Martin | Stunt Coordinator |
| Production | Lizz Grant | Production Coordinator |
| Art | Stephen Alesch | Art Direction |
| Costume & Make-Up | Frank L. Fleming | Assistant Costume Designer |
| Sound | Jonathan Karp | Music Editor |
| Visual Effects | Carole Cowley | Visual Effects Producer |
| Production | Jerry Jaffe | Location Manager |
| Sound | Harold Burke | Foley |
| Sound | Bill Meadows | Sound Recordist |
| Camera | Caesar S. Carnevale | Camera Loader |
| Crew | Joanne Lamstein | Stunt Double |
| Art | Patrick Denver | Special Props |
| Directing | Amy Sayres | First Assistant Director |
| Costume & Make-Up | Karen Dahl | Makeup Artist |
| Camera | Mitchell Andrew Lillian | First Company Grip |
| Editing | Kent Blocher | Assistant Editor |
| Costume & Make-Up | Sandi Figueroa | Costumer |
| Art | Russ J. Griffon | Assistant Property Master |
| Visual Effects | Jeffrey Caruso | Visual Effects Production Assistant |
| Directing | Maggie Murphy | Second Assistant Director |
| Directing | Bradley Morris | Second Second Assistant Director |
| Sound | Hilda Hodges | Foley Artist |
| Sound | Joel Shryack | ADR Editor |
| Art | Kyle Cooper | Title Designer |
| Visual Effects | Lawrence Carroll | Visual Effects Compositor |
| Crew | Donald John Hewitt | Stunt Double |
| Camera | Alexander Griffiths | Second Company Grip |
| Costume & Make-Up | Chris Ann Pappas | Costume Assistant |
| Costume & Make-Up | Monica Ruiz-Ziegler | Costume Coordinator |
| Sound | Bob Baron | ADR Mixer |
| Camera | Paul Candrilli | Dolly Grip |
| Production | Nadia Lubbe Simon | Casting Assistant |
| Art | Richard Hebrank | Construction Grip |
| Sound | Shawn Kennelly | Foley Mixer |
| Art | John Davis | Storyboard Artist |
| Crew | Barry Williams | Visual Effects Editor |
| Camera | Amanda Hudson | Second Assistant Camera |
| Production | Jose Cabrera | Production Secretary |
| Lighting | Jay Fortune | Chief Lighting Technician |
| Production | Edward E. Giddens | Assistant Accountant |
| Production | Michelle Dunton | Script Researcher |
| Production | Linda 'Sam' Glynn | Assistant Location Manager |
| Production | Rick Tropasso | First Assistant Accountant |
| Lighting | Roy Bennett | Lighting Design |
| Lighting | Ron Alexus | Assistant Chief Lighting Technician |
| Editing | Mary Nelson-Duerrstein | Negative Cutter |
| Crew | Joseph Garzero | Charge Scenic Artist |
| Sound | Nicholas Dodd | Conductor |
| Production | Sylvia Fay | Extras Casting |
| Production | Edith Hagigi | Executive Assistant |
| Production | Adeline Colangelo | Production Assistant |
| Writing | Narges Takesh | Story Editor |
| Crew | Wayne Petrucelli | Security Coordinator |
| Production | Matthew Spiegel | Assistant Production Coordinator |
