De rechercheurs Martin Riggs, Roger Murtaugh en Lorna Cole zijn terug, samen met de hyperactieve Leo Getz. Het viertal wordt ditmaal bijgestaan door assistent-rechercheur Lee Butters in hun onderzoek naar de mensensmokkel die georganiseerd wordt door een Aziatische misdaadorganisatie. Ze worden al snel geconfronteerd met Wan Sing Ku, de harde man in de organisatie. Dan blijkt al snel dat het oprollen van deze Chinese maffia-bende een zware, dodelijke klus zou kunnen worden voor Riggs en Murtaugh.
Nee, helaas is Lethal Weapon 4 nog niet beschikbaar op Netflix in Nederland.
| Directing | Richard Donner | Director |
| Production | Richard Donner | Producer |
| Writing | Channing Gibson | Screenplay |
| Production | Joel Silver | Producer |
| Sound | Eric Clapton | Original Music Composer |
| Sound | Michael Kamen | Original Music Composer |
| Sound | David Sanborn | Original Music Composer |
| Camera | Andrzej Bartkowiak | Director of Photography |
| Editing | Dallas Puett | Editor |
| Editing | Kevin Stitt | Editor |
| Editing | Eric Strand | Editor |
| Editing | Frank J. Urioste | Editor |
| Production | Marion Dougherty | Casting |
| Art | J. Michael Riva | Production Design |
| Art | Lauri Gaffin | Set Decoration |
| Art | David F. Klassen | Art Direction |
| Art | Richard F. Mays | Art Direction |
| Costume & Make-Up | Ha Nguyen | Costume Design |
| Sound | Lou Kleinman | Sound Effects Editor |
| Crew | Billy D. Lucas | Stunts |
| Crew | Danny Epper | Stunts |
| Crew | Mic Rodgers | Stunt Coordinator |
| Crew | Kenny Endoso | Stunts |
| Crew | Michael Runyard | Stunts |
| Production | Steve Perry | Executive Producer |
| Production | Jim Van Wyck | Executive Producer |
| Crew | Al Goto | Stunts |
| Crew | Tim Trella | Stunts |
| Writing | Shane Black | Characters |
| Writing | Jonathan Lemkin | Story |
| Writing | Alfred Gough | Story |
| Writing | Miles Millar | Story |
| Production | Dan Cracchiolo | Co-Producer |
| Production | Spencer Franklin | Associate Producer |
| Production | J. Mills Goodloe | Co-Producer |
| Production | Jennifer Gwartz | Associate Producer |
| Production | Ilyse A. Reutlinger | Associate Producer |
| Crew | Doc Duhame | Stunts |
| Crew | Michiko Nishiwaki | Stunts |
| Crew | Tommy J. Huff | Stunts |
| Crew | Lisa Hoyle | Stunts |
| Crew | Henry Kingi Jr. | Stunts |
| Crew | Patricia M. Peters | Stunts |
| Camera | Steven J. Winslow | Camera Technician |
| Camera | Bobby Brown | First Assistant Camera |
| Camera | Michael J. Coo | Key Grip |
| Camera | Robert Ikeda | Grip |
| Camera | Hans Bjerno | Aerial Director of Photography |
| Camera | Bill Brummond | Steadicam Operator |
| Camera | Andrew Cooper | Still Photographer |
| Camera | Pete Romano | Underwater Camera |
| Costume & Make-Up | Kimberly Guenther Durkin | Costume Supervisor |
| Costume & Make-Up | Kareen Boursier | Hairstylist |
| Costume & Make-Up | Charlene Johnson | Key Hair Stylist |
| Costume & Make-Up | Lisa Deveaux | Makeup Artist |
| Costume & Make-Up | Charlene Amateau | Set Costumer |
| Costume & Make-Up | Jeff Hay | Set Dressing Artist |
| Crew | David Fencl | Armorer |
| Crew | Peter Roderick | Carpenter |
| Crew | Huan-Chiu Ku | Martial Arts Choreographer |
| Crew | Ernest H. Lauterio | Craft Service |
| Crew | Jerome Butler | Dialect Coach |
| Crew | Gil Amaral | Driver |
| Crew | Ilyse A. Reutlinger | Post Production Supervisor |
| Crew | Thomas S. Dickson | Projection |
| Art | Erik L. Nelson | Property Master |
| Crew | Louis Farah | Set Medic |
| Crew | Jon G. Belyeu | Special Effects Coordinator |
| Crew | Conrad E. Palmisano | Stunt Coordinator |
| Crew | Bruce Paul Barbour | Stunts |
| Crew | Frank Roughan | Transportation Captain |
| Crew | John M. Woodward | Transportation Coordinator |
| Production | R. Anthony Brown | Unit Production Manager |
| Crew | Andrew Lipschultz | Unit Publicist |
| Crew | Cory Fleming | Utility Stunts |
| Crew | Martin Glover | Video Assist Operator |
| Directing | J. Tom Archuleta | First Assistant Director |
| Editing | Dale E. Grahn | Color Timer |
| Lighting | Tasso Bravos | Best Boy Electric |
| Lighting | Christian J. Killingsworth | Electrician |
| Lighting | Scott Kidner | Lighting Technician |
| Lighting | Richard Hartley | Rigging Gaffer |
| Lighting | Robert J. Reilly | Rigging Grip |
| Production | Douglas Wright | Casting Associate |
| Production | Michael Haro | Location Manager |
| Production | Thomas A. Davila | Production Accountant |
| Sound | Todd Bassman | Boom Operator |
| Sound | Baylis Glascock | Assistant Sound Editor |
| Sound | Ezra Dweck | Foley Editor |
| Sound | Zigmund Gron | Music Editor |
| Sound | Chris Boardman | Orchestrator |
| Sound | Tim Cooney | Production Sound Mixer |
| Sound | John Pospisil | Sound Designer |
| Sound | Richard L. Anderson | Sound Effects Editor |
| Sound | Mark Mangini | Supervising Sound Editor |
| Visual Effects | Cristin Pescosolido | Digital Compositors |
| Visual Effects | Bill Maher | Visual Effects Coordinator |
| Visual Effects | David Taritero | Visual Effects Producer |
| Visual Effects | Michael L. Fink | Visual Effects Supervisor |
| Crew | Laura Gary | Studio Teachers |
| Sound | Mark Kenna | Dolby Consultant |
| Production | Geoff Johns | Co-Producer |
| Art | Wendy Riva | Assistant Art Director |
| Art | Walt Hadfield | Construction Coordinator |
| Art | James F. Walker | Construction Foreman |
| Art | Carlo Basail | Greensman |
| Art | Marc Baird | Production Illustrator |
| Art | Charisse Cardenas | Set Designer |
| Art | Bill 'Kauhane' Hoyt | Standby Painter |
| Camera | Steve Adcock | Additional Camera |
| Camera | Ray De La Motte | Camera Operator |
| Crew | Norman Howell | Stunts |
| Crew | Cheryl Wheeler Duncan | Stunt Double |
| Crew | Erik Cord | Stunts |
| Crew | Troy Gilbert | Stunts |
| Crew | Tim Gilbert | Stunts |
| Crew | Jeff Imada | Stunts |
| Crew | Thomas Rosales Jr. | Stunts |
| Crew | Annie Ellis | Stunts |
| Crew | Jennifer Caputo | Stunts |
| Crew | Ronnie Rondell Jr. | Stunts |
| Sound | Gregg Rudloff | Sound Re-Recording Mixer |
| Crew | Henry Kingi | Stunts |
| Crew | Tony Brubaker | Stunt Double |
| Crew | Marcus Miller | Additional Music |
| Sound | Avram D. Gold | Supervising Dialogue Editor |
| Directing | Conrad E. Palmisano | Second Unit Director |
| Sound | Susan Dudeck | Dialogue Editor |
| Sound | William C. Carruth | ADR Editor |
| Sound | Marshall Winn | ADR Editor |
| Sound | James Simcik | Supervising ADR Editor |
| Crew | Gary McLarty | Stunts |
| Crew | Lance Gilbert | Stunt Double |
| Directing | Mic Rodgers | Second Unit Director |
| Crew | Gregory J. Barnett | Stunts |
| Crew | John C. Meier | Stunts |
| Sound | Stephen McLaughlin | Music Score Producer |
| Crew | Buddy Joe Hooker | Stunts |
| Crew | Jill Brown | Stunts |
| Crew | Jimmy N. Roberts | Stunts |
| Directing | David Ascher | Second Second Assistant Director |
| Art | Christopher Amy | Assistant Property Master |
| Sound | Troy Porter | ADR Mixer |
| Sound | Josephine Nericcio | Assistant Dialogue Editor |
| Sound | Eric Gotthelf | Foley Mixer |
| Sound | Carolyn Tapp | Foley Recordist |
| Crew | Richard Castro | Special Effects Assistant |
| Crew | Tom von Badinski | Special Effects Technician |
| Crew | Troy Brown | Stunt Double |
| Crew | Rick Sawaya | Stunt Driver |
| Camera | Chris Bangma | Assistant Camera |
| Camera | Jacobus Marcus | Camera Loader |
| Camera | Nico Bally | Dolly Grip |
| Camera | Christopher Blauvelt | Second Assistant Camera |
| Editing | Jonathan Malden | Colorist |
| Editing | Mo Henry | Negative Cutter |
| Production | Geoff Harding | Assistant Location Manager |
| Sound | Michael Kamen | Conductor |
| Production | Jason S. Gondek | Accountant |
| Lighting | Stanley L. Gonsales | Assistant Chief Lighting Technician |
| Lighting | James B. Crawford | Chief Lighting Technician |
| Visual Effects | Dan Levitan | Compositing Supervisor |
| Production | Cynthia Neber | Executive Assistant |
| Production | Jodie Thomas | Production Assistant |
| Production | Lisa Matsukawa | Production Secretary |
| Crew | Art Fransen | Technical Advisor |
| Crew | Dick Hancock | Stunts |
| Crew | George Fisher | Stunts |
