Nadat Alison Jones door een stom toeval hoort, dat haar aanstaande Sam met zijn ex-vrouw naar bed is geweest, wijst ze hem direct het gat van de deur. Dat betekent wel, dat ze vanaf dat moment alleen in een groot appartement in een nogal sinistere buurt. Allie besluit een advertentie te plaatsen voor een kamergenote. Hedra Carlson is een geschenk uit de hemel. Het ingetogen meisje is dankbaar voor de kamer die ze met Allie mag delen. Wel eist Hedy dat Sam in geen geval meer terug komt om haar plaats weer in te nemen, maar Allie stelt haar gerust. Meer en meer trekken de meisjes met elkaar op, totdat Allie onaangenaam verrast wordt door Hedy, die zich langzamerhand alle uiterlijke kenmerken van haar kamergenote gaat aanmeten. Dan komt Sam plotseling weer opdagen en dat bevalt Hedy niet. Voor Allie's ogen voltrekt zich een beangstigende verandering. De perfecte kamergenote wordt de huiveringwekkendste nachtmerrie.
Nee, helaas is Single White Female nog niet beschikbaar op Netflix in Nederland.
| Camera | Luciano Tovoli | Director of Photography |
| Production | Barbet Schroeder | Producer |
| Directing | Barbet Schroeder | Director |
| Editing | Lee Percy | Editor |
| Production | Jack Baran | Executive Producer |
| Sound | Howard Shore | Original Music Composer |
| Writing | Don Roos | Screenplay |
| Writing | John Lutz | Novel |
| Crew | Jamie Jo Medearis | Stunts |
| Costume & Make-Up | Eileen Kennedy | Costume Supervisor |
| Art | Walt Hadfield | Construction Coordinator |
| Sound | E. Jeane Putnam | Sound Editor |
| Sound | Carl Fischer | Boom Operator |
| Art | James F. Walker | Construction Foreman |
| Camera | Bob Hall | First Assistant Camera |
| Camera | Gary Dagg | Key Grip |
| Sound | Jim Weidman | Music Editor |
| Sound | Richard Beggs | Sound Re-Recording Mixer |
| Camera | François Duhamel | Still Photographer |
| Editing | Sarah Peddie | Assistant Editor |
| Crew | Eddie Surkin | Special Effects |
| Camera | Joe Kelly | Best Boy Grip |
| Sound | Gary Rydstrom | Sound Designer |
| Directing | Daniel R. Suhart | Second Assistant Director |
| Camera | Monty Rowan | Camera Operator |
| Camera | Brian LeGrady | Second Assistant Camera |
| Production | Margaret Mitchell | Production Accountant |
| Crew | Joni Avery | Stunts |
| Lighting | David Burnett | Assistant Chief Lighting Technician |
| Camera | David Nims | Dolly Grip |
| Art | James F. Truesdale | Assistant Art Director |
| Costume & Make-Up | Jaqueline De La Fontaine | Costumer |
| Crew | Edward J. Ulrich | Stunt Coordinator |
| Sound | Ethan Van der Ryn | Sound Editor |
| Sound | Marilyn McCoppen | Sound Editor |
| Production | Roger Joseph Pugliese | Unit Production Manager |
| Editing | Emily Wallin | Assistant Editor |
| Production | Elyse Katz | Production Coordinator |
| Sound | Claire Sanfilippo | Assistant Sound Editor |
| Sound | Don Hall | Sound Editor |
| Sound | Gwendolyn Yates Whittle | Sound Editor |
| Sound | Christopher Boyes | Assistant Sound Designer |
| Sound | Tom Myers | Assistant Sound Designer |
| Crew | Beverly Walker | Unit Publicist |
| Art | Robert Dawson | Title Designer |
| Sound | Gloria S. Borders | Supervising Sound Editor |
| Sound | J.R. Grubbs | Assistant Sound Editor |
| Costume & Make-Up | Elisabetta Beraldo | Assistant Costume Designer |
| Lighting | Mike Moyer | Chief Lighting Technician |
| Crew | Tom Briggs | Transportation Coordinator |
| Sound | Ken Fischer | Sound Editor |
| Directing | Wilma Garscadden-Gahret | Script Supervisor |
| Art | Douglas E. Maxwell | Leadman |
| Production | Jakki Fink | Casting Assistant |
| Sound | Robert Shoup | Sound Editor |
| Sound | Gary Rydstrom | Sound Re-Recording Mixer |
| Sound | Tim Holland | Supervising Sound Editor |
| Sound | Tom Johnson | Sound Re-Recording Mixer |
| Crew | James Brown | Transportation Captain |
| Production | Howard Feuer | Casting |
| Costume & Make-Up | Lizbeth Williamson | Makeup Artist |
| Costume & Make-Up | Matthew W. Mungle | Special Effects Makeup Artist |
| Costume & Make-Up | Milena Canonero | Costume Design |
| Art | Milena Canonero | Production Design |
| Costume & Make-Up | Candace Neal | Hairstylist |
| Production | Roger Joseph Pugliese | Co-Producer |
| Art | Anne H. Ahrens | Set Decoration |
| Production | Susan Hoffman | Associate Producer |
| Art | P. Michael Johnston | Art Direction |
