Een groep strijders heeft zes dagen de tijd om de wereld te redden van de duivelse Shoa Kahn. Als ze hem en zijn strijders niet verslaan tijdens het tournooi Mortal Kombat zal de Aarde worden samengevoegd met Outworld, en zal Kahn de ultieme machthebber worden
Nee, helaas is Mortal Kombat: Annihilation nog niet beschikbaar op Netflix in Nederland.
| Directing | John R. Leonetti | Director |
| Production | Lawrence Kasanoff | Producer |
| Production | Brian Witten | Executive Producer |
| Crew | Dana Hee | Stunt Double |
| Crew | Ed Boon | Video Game |
| Crew | John Tobias | Video Game |
| Art | Simon Wakefield | Set Decoration |
| Costume & Make-Up | Shaune Harrison | Special Effects Makeup Artist |
| Costume & Make-Up | Gary Pollard | Makeup Effects Designer |
| Costume & Make-Up | Matt Jordon | Special Effects Makeup Artist |
| Directing | Pat E. Johnson | Second Unit Director |
| Directing | Apichart Chusakul | First Assistant Director |
| Directing | Lee Cleary | First Assistant Director |
| Directing | Jamie Christopher | Second Assistant Director |
| Directing | Eddie Stacey | Second Unit Director |
| Sound | Ken Teaney | Sound Re-Recording Mixer |
| Sound | David Farmer | Sound Designer |
| Crew | Ron Trost | Special Effects Coordinator |
| Visual Effects | Joss Williams | Special Effects Supervisor |
| Crew | Joss Williams | Special Effects |
| Crew | Mark Caso | Stunts |
| Crew | Keith Cooke | Stunts |
| Crew | Jeff Hewitt-Davis | Stunts |
| Crew | Carlton Headley | Stunts |
| Crew | Pat E. Johnson | Stunt Coordinator |
| Crew | Dennis Keiffer | Stunts |
| Crew | Theo Kypri | Stunts |
| Crew | John Medlen | Stunts |
| Crew | Valentino Musetti | Stunts |
| Crew | J.J. Perry | Stunts |
| Crew | Ray Park | Stunt Double |
| Crew | Robin Shou | Fight Choreographer |
| Crew | Nikki Berwick | Stunts |
| Crew | 谷垣健治 | Stunt Double |
| Crew | Eddie Stacey | Stunt Coordinator |
| Crew | 徐寶華 | Stunts |
| Crew | Tyrone C. Wiggins | Stunts |
| Crew | Mark Caso | Stunt Double |
| Crew | Sultan Uddin | Stunts |
| Crew | Keith Cooke | Fight Choreographer |
| Crew | Dennis Keiffer | Stunt Double |
| Crew | Theo Kypri | Stunt Double |
| Crew | Tony Jaa | Stunt Double |
| Crew | Buster Reeves | Stunt Double |
| Crew | Nikki Berwick | Stunt Double |
| Crew | Tyrone C. Wiggins | Stunt Double |
| Lighting | Pat Blymyer | Gaffer |
| Lighting | Logan Leabo | Gaffer |
| Camera | Christopher Faloona | Second Unit Director of Photography |
| Sound | George S. Clinton | Original Music Composer |
| Production | Carla Fry | Executive Producer |
| Production | Alison Savitch | Executive Producer |
| Writing | Lawrence Kasanoff | Story |
| Writing | Joshua Wexler | Story |
| Writing | John Tobias | Story |
| Writing | Brent V. Friedman | Screenplay |
| Writing | Bryce Zabel | Screenplay |
| Production | Thom Fleming | Line Producer |
| Production | Gerrit V. Folsom | Line Producer |
| Production | Kevin Reidy | Co-Producer |
| Production | Joshua Wexler | Associate Producer |
| Editing | Peck Prior | Editor |
| Production | Fern Champion | Casting |
| Production | Mark Paladini | Casting |
| Art | Charles Wood | Production Design |
| Art | Nathan Schroeder | Art Direction |
| Costume & Make-Up | Jennifer L. Parsons | Costume Design |
| Costume & Make-Up | Melissa Lackersteen | Key Makeup Artist |
| Costume & Make-Up | Michelle Taylor | Key Makeup Artist |
| Camera | Matthew F. Leonetti | Director of Photography |
| Costume & Make-Up | Chris Lyons | Special Effects Makeup Artist |
