Het honkbalteam The Cleveland Indians heeft in 34 jaar geen succes behaald. Voormalig nachtclubdanseres Rachel Phelps trouwt de eigenaar van het team. Hij overleeft de huwelijksreis niet, en zij erft het team van hem. Zij haat Cleveland, en wil graag een nieuw stadion betrekken in een warmer klimaat, zoals Miami, Florida. De enige manier waarop zij onder het contract met Cleveland uit kan komen, is wanneer het bezoekersaantal onder de 800.000 komt. Om dat te bereiken stelt ze het slechts denkbare team samen. Wanneer het team er achter komt wat de bedoeling van Rachel Phelps is, besluiten ze terug te vechten.
Nee, helaas is Major League nog niet beschikbaar op Netflix in Nederland.
| Production | Chris Chesser | Producer |
| Production | Mark Rosenberg | Executive Producer |
| Directing | David S. Ward | Director |
| Production | Joanne Zaluski | Casting |
| Production | Irby Smith | Producer |
| Camera | Reynaldo Villalobos | Director of Photography |
| Art | Jeffrey Howard | Production Design |
| Costume & Make-Up | Erica Edell Phillips | Costume Design |
| Production | Julie Bergman Sender | Co-Producer |
| Sound | James Newton Howard | Original Music Composer |
| Directing | Louis D'Esposito | First Assistant Director |
| Costume & Make-Up | Sherrie Brody | Wardrobe Assistant |
| Directing | Christine Larson | Second Assistant Director |
| Crew | G.A. Aguilar | Stunts |
| Costume & Make-Up | Peggy Teague | Makeup & Hair Assistant |
| Art | Bill Rea | Set Designer |
| Sound | Laura Derrick | Boom Operator |
| Costume & Make-Up | Frances Mathias | Hairstylist |
| Production | Edward D. Markley | Unit Production Manager |
| Directing | Richard Patrick | Second Assistant Director |
| Crew | Rick LeFevour | Stunt Coordinator |
| Costume & Make-Up | John Wabisca | Makeup Artist |
| Art | Patrick Cassidy | Assistant Set Decoration |
| Directing | Jerry Grandey | First Assistant Director |
| Art | Celeste Lee | Set Decoration |
| Sound | Susumu Tokunow | Sound Mixer |
| Costume & Make-Up | Laurie Hudson | Wardrobe Supervisor |
| Crew | Ted White | Stunts |
| Directing | Irby Smith | Second Unit Director |
| Costume & Make-Up | Michael Becker | Costume Supervisor |
| Costume & Make-Up | Patti Cameron | Wardrobe Assistant |
| Production | Irby Smith | Unit Production Manager |
| Camera | James Pergola | Second Unit Director of Photography |
| Editing | Dennis M. Hill | Editor |
| Costume & Make-Up | Judith Denny | Makeup & Hair Assistant |
| Crew | Alex Flores | Stunts |
| Crew | Stacy Logan | Stunts |
| Crew | Michael F. Twarog | Stunts |
| Editing | Tony Lombardo | Editor |
| Art | John Krenz Reinhart Jr. | Art Direction |
| Crew | Dieter Sturm | Special Effects |
| Sound | Randy Newman | Songs |
| Writing | David S. Ward | Writer |
